Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Justyna Róg"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Mortality of Duchenne Muscular Dystrophy (DMD) is a consequence of progressive wasting of skeletal and cardiac muscle, where dystrophinopathy affects not only muscle fibres but also myogenic cells. Elevated activity of P2X7 receptors and inc
Externí odkaz:
https://doaj.org/article/e1cce0c2c23a422ab87448d43fb7c223
Autor:
Maxime RF Gosselin, Virginie Mournetas, Malgorzata Borczyk, Suraj Verma, Annalisa Occhipinti, Justyna Róg, Lukasz Bozycki, Michal Korostynski, Samuel C Robson, Claudio Angione, Christian Pinset, Dariusz C Gorecki
Publikováno v:
eLife, Vol 11 (2022)
Duchenne muscular dystrophy (DMD) affects myofibers and muscle stem cells, causing progressive muscle degeneration and repair defects. It was unknown whether dystrophic myoblasts—the effector cells of muscle growth and regeneration—are affected.
Externí odkaz:
https://doaj.org/article/6e98c057ed4b4500b5bfe008d1e51f41
Autor:
Robin M. H. Rumney, Justyna Róg, Natalia Chira, Alexander P. Kao, Rasha Al-Khalidi, Dariusz C. Górecki
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Ectopic calcification (EC) of myofibers is a pathological feature of muscle damage in Duchenne muscular dystrophy (DMD). Mineralisation of muscle tissue occurs concomitantly with macrophage infiltration, suggesting a link between ectopic mineral depo
Externí odkaz:
https://doaj.org/article/37e4dfc22c994e55a84943a00d70969a
Autor:
Rasha Al-Khalidi, Chiara Panicucci, Paul Cox, Natalia Chira, Justyna Róg, Christopher N. J. Young, Rhiannon E. McGeehan, Kameshwari Ambati, Jayakrishna Ambati, Krzysztof Zabłocki, Elisabetta Gazzerro, Stephen Arkle, Claudio Bruno, Dariusz C. Górecki
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-17 (2018)
Abstract Duchenne muscular dystrophy (DMD) is the most common inherited muscle disorder that causes severe disability and death of young men. This disease is characterized by progressive muscle degeneration aggravated by sterile inflammation and is a
Externí odkaz:
https://doaj.org/article/dd25d786045a4ae7b7f3c0189e811271
Autor:
Maxime RF Gosselin, Virginie Mournetas, Malgorzata Borczyk, Suraj Verma, Annalisa Occhipinti, Justyna Róg, Lukasz Bozycki, Michal Korostynski, Samuel C Robson, Claudio Angione, Christian Pinset, Dariusz C Gorecki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd8e137fdb90207a89e7c8f06914349e
https://doi.org/10.7554/elife.75521.sa2
https://doi.org/10.7554/elife.75521.sa2
Mortality of Duchenne Muscular Dystrophy (DMD) is a direct consequence of progressive wasting of muscle fibres leading to skeletal muscle deterioration and cardiomyopathy. However pathophysiological effects of mutations in the dystrophin encoding gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a62877f11c5f84ffd0e772577c39a67
https://doi.org/10.1101/2022.02.16.478175
https://doi.org/10.1101/2022.02.16.478175
Autor:
Maxime R. F. Gosselin, Virginie Mournetas, Malgorzata Borczyk, Suraj Verma, Annalisa Occhipinti, Justyna Róg, Lukasz Bozycki, Michal Korostynski, Samuel C. Robson, Claudio Angione, Christian Pinset, Dariusz C. Górecki
Background Duchenne muscular dystrophy (DMD) is the most common inherited muscle disease that leads to severe disability and death in young men. DMD is caused by out-of-frame mutations in the largest known gene, which encodes dystrophin. The loss of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e367bcfcfd595eaa64d2b421433ca45
https://doi.org/10.1101/2021.08.24.457331
https://doi.org/10.1101/2021.08.24.457331
Autor:
Maxime R. F. Gosselin, Natalia Nowak, Wojciech Brutkowski, Dorota Dymkowska, Dariusz C. Górecki, Justyna Róg, Krzysztof Zabłocki, Aleksandra Oksiejuk, Samuel Robson
Publikováno v:
Róg, J, Oksiejuk, A, Gosselin, M R F, Brutkowski, W, Dymkowska, D, Nowak, N, Robson, S, Górecki, D C & Zabłocki, K 2019, ' Dystrophic mdx mouse myoblasts exhibit elevated ATP/UTP-evoked metabotropic purinergic responses and alterations in calcium signalling ', Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease . https://doi.org/10.1016/j.bbadis.2019.01.002
Pathophysiology of Duchenne Muscular Dystrophy (DMD) is still elusive. Although progressive wasting of muscle fibres is a cause of muscle deterioration, there is a growing body of evidence that the triggering effects of DMD mutation are present at th
Autor:
Elżbieta, Krasowska, Justyna, Róg, Anthony, Sinadinos, Christopher N J, Young, Dariusz C, Górecki, Krzysztof, Zabłocki
Publikováno v:
Postepy biochemii. 60(4)
The P2 purinergic (nucleotide) receptor super-family comprises of two families of protein. The P2X, which are channel-forming ionotropic receptors and the P2Y metabotropic receptors activating G protein-mediated signalling pathways. Members of both g
Autor:
Marta Onopiuk, Christopher N. J. Young, Wojciech Brutkowski, Justyna Róg, Sylwia Wojciechowska, Dariusz C. Górecki, Stephen Arkle, Elżbieta Krasowska, Krzysztof Zabłocki, Morten Ritso
Publikováno v:
Onopiuk, M, Brutkowski, W, Young, C, Krasowska, E, Rog, J, Ritso, M, Wojciechowska, S, Arkle, S, Zablocki, K & Gorecki, D C 2015, ' Store-operated calcium entry contributes to abnormal Ca 2+ signalling in dystrophic mdx mouse myoblasts ', Archives of Biochemistry and Biophysics, vol. 569, pp. 1-9 . https://doi.org/10.1016/j.abb.2015.01.025
Sarcolemma damage and activation of various calcium channels are implicated in altered Ca2+ homeostasis in muscle fibres of both Duchenne muscular dystrophy (DMD) sufferers and in the mdx mouse model of DMD. Previously we have demonstrated that also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abbe796855b39cba52023a8e409fab15
http://hdl.handle.net/2086/15031
http://hdl.handle.net/2086/15031