Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Justyna Ogonek"'
Autor:
Pavankumar Reddy Varanasi, Justyna Ogonek, Susanne Luther, Elke Dammann, Michael Stadler, Arnold Ganser, Sylvia Borchers, Lothar Hambach, Eva M Weissinger
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213739 (2019)
Leukemia relapse is the main cause for mortality after allogeneic stem cell transplantation (allo-SCT). Donor-derived allo-immune responses eliminate the residual host hematopoiesis and protect against relapse. Cytomegalovirus (CMV) reactivation (CMV
Externí odkaz:
https://doaj.org/article/708b53e5958d4dfb892a7d5de6fd6105
Autor:
Kriti Verma, Justyna Ogonek, Pavankumar Reddy Varanasi, Susanne Luther, Ivonne Bünting, Katrin Thomay, Yvonne Lisa Behrens, Eva Mischak-Weissinger, Lothar Hambach
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177405 (2017)
End-stage differentiation of antigen-specific T-cells may precede loss of immune responses against e.g. viral infections after allogeneic stem cell transplantation (SCT). Antigen-specific CD8+ T-cells detected by HLA/peptide multimers largely compris
Externí odkaz:
https://doaj.org/article/9fa51c76f06347ed929430c4640da00c
Autor:
Justyna Ogonek, Mateja Kralj Juric, Sakhila Ghimire, Pavankumar Varanasi, Ernst Holler, Hildegard Greinix, Eva Weissinger
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
The reconstitution and the regaining of function of a healthy, transplanted immune system is of utmost importance for the recovery and long term survival of patients after HSCT. New developments within HSCT, for example, umbilical cord blood or haplo
Externí odkaz:
https://doaj.org/article/92f3dcfd07ec477fbac18ab81b5c6235
Autor:
Monica Reis, Justyna Ogonek, Marsela Qesari, Nuno M Borges, Lindsay Nicholson, Liane Preußner, Anne Mary Dickinson, Xiao-nong Wang, Eva Maria Weissinger, Anne Richter
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Allogeneic HSCT is associated with serious complications and improvement of the overall clinical outcome of patients with hematological malignancies is necessary. During the last decades, post-transplant donor-derived adoptive cellular immunotherapeu
Externí odkaz:
https://doaj.org/article/58b640cb5be04c61ae2c51f4ec3bef32
Autor:
Sudipta Das, Maria Czarnek, Monika Bzowska, Renata Mężyk-Kopeć, Krystyna Stalińska, Barbara Wyroba, Jolanta Sroka, Jarosław Jucha, Dawid Deneka, Paulina Stokłosa, Justyna Ogonek, Melody A Swartz, Zbigniew Madeja, Joanna Bereta
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50791 (2012)
ADAM17 (a disintegrin and metalloprotease 17) is a major sheddase for numerous growth factors, cytokines, receptors, and cell adhesion molecules and is often overexpressed in malignant cells. It is generally accepted that ADAM17 promotes tumor develo
Externí odkaz:
https://doaj.org/article/8656bee2c12d4a449e7fa9ea5ac56467
Autor:
Christine Hörth, A Nottebrock, M. Benmebarek, Justyna Ogonek, Stefanie Lesch, Philipp Metzger, Sebastian Kobold, Stefan Endres, S Stoiber, Bruno L. Cadilha, Adrian Gottschlich
Publikováno v:
E-Poster Presentations.
Background Chimeric antigen receptor (CAR) T cell therapy is currently approved for the treatment of some hematological malignancies. However, CAR T cells have so far lacked efficacy in the treatment of solid tumors. A major hurdle of CAR T cell ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1644d3a9d761244e1d903a337ec5b376
https://doi.org/10.1136/jitc-2020-itoc7.86
https://doi.org/10.1136/jitc-2020-itoc7.86
Autor:
Slavoljub Milosevic, Krystel Vincent, Daniel Sommermeyer, Dolores J. Schendel, Alexander Schmidt, Barbara Loesch, Adriana Turqueti Neves, Alexandra Kuhlenkamp, Andreas Acs, Tiziana Franceschetti, Justyna Ogonek, Claude Perreault
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A201-A201
BackgroundTransgenic T cell receptor (TCR)-based T cell therapies are a powerful treatment for cancer. However, one of the greatest remaining challenges is the successful identification of tumor-specific antigens (TSAs) that are shared between patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::363f4f9cbb448c797e92f4a388d2e9f4
https://doi.org/10.1136/jitc-2021-sitc2021.189
https://doi.org/10.1136/jitc-2021-sitc2021.189
Autor:
Alessia Nottebrock, Eric Tartour, Klaus-Peter Janssen, Nicholas Tokarew, Christine Hoerth, Moritz Thomas, Johannes Lutz, Niels Halama, Martin Jastroch, Öykü Umut, Simon Grassmann, Andrew S. Liss, Maximilian Reichert, Stefanie Lesch, Philipp Metzger, S Stoiber, Benjamin Larimer, Justyna Ogonek, Bruno L. Cadilha, M. Kurzay, Jasper N. Pruessmann, Felicitas Rataj, Mauro Di Pilato, Max Schnurr, Viktoria Blumenberg, Stephan Kruger, Sebastian Kobold, Matthias Seifert, Lene Vimeux, Zahra Dantes, Carsten Marr, Klara Dorman, M. Benmebarek, C. Karches, Moritz Rapp, Duc Huynh, Stefan Endres, Lars M. König, Thi Anh-Dao Tran, Constanze Heise, Dario Dhoqina, Daniel Lamp, Marion Subklewe, Thorsten R. Mempel, Emmanuel Donnadieu, Ruth Grünmeier, Anna Reischer, Svenja Ruehland, Michael Hristov, Adrian Gottschlich, Taisuke Baba, Peter Duewell, Steffen Ormanns, Sandy Joaquina, Simon Rothenfusser, Thomas Hank, Arman Oener, Remco T. A. Megens
Publikováno v:
Nature biomedical engineering
Nature Biomedical Engineering
Nature Biomedical Engineering, 5(11). Nature Publishing Group
Nat. Bio. Eng. 5, 1246-1260 (2021)
Nature Biomedical Engineering
Nature Biomedical Engineering, 5(11). Nature Publishing Group
Nat. Bio. Eng. 5, 1246-1260 (2021)
Forced expression of C-X-C chemokine receptor type 6 in antigen-specific T cells enhanced the recognition and lysis of pancreatic cancer cells and the efficacy of adoptive cell therapy for pancreatic cancer.The efficacy of adoptive cell therapy for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a8181fb1f294ecbde99e30db0ad5a6
https://doi.org/10.1038/s41551-021-00737-6
https://doi.org/10.1038/s41551-021-00737-6
Autor:
Eva M. Weissinger, Lothar Hambach, Pavankumar Reddy Varanasi, Ulrike Koehl, Patrick Schweier, Justyna Ogonek, Susanne Luther, Elke Dammann, Arnold Ganser, Gudrun Göhring, Sylvia Borchers, Michael Stadler, Wolfgang Kühnau
Publikováno v:
Biology of Blood and Marrow Transplantation. 23:1046-1053
Complete donor chimerism is strongly associated with complete remission after allogeneic stem cell transplantation (allo-SCT) in patients with hematologic malignancies. Donor-derived allo-immune responses eliminate the residual host hematopoiesis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10401de2ff7dd1d8c04b3ebacd7a8ada
https://doi.org/10.1016/j.bbmt.2017.03.027
https://doi.org/10.1016/j.bbmt.2017.03.027
Autor:
Justyna Ogonek, Sebastian Kobold, Nicholas Tokarew, Michael von Bergwelt-Baildon, Stefan Endres
Publikováno v:
British Journal of Cancer
Adoptive T cell therapy (ACT) refers to the therapeutic use of T cells. T cells genetically engineered to express chimeric antigen receptors (CAR) constitute the most clinically advanced form of ACT approved to date for the treatment of CD19-positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8f91b17638578ebaa4a8cddc9c9d9a