Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Justyna M. Kowal"'
Apigenin and Rutaecarpine reduce the burden of cellular senescence in bone marrow stromal stem cells
Autor:
Dalia Ali, Meshail Okla, Sarah Abuelreich, Radhakrishnan Vishnubalaji, Nicholas Ditzel, Rimi Hamam, Justyna M. Kowal, Ahmed Sayed, Abdullah Aldahmash, Nehad M. Alajez, Moustapha Kassem
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionOsteoporosis is a systemic age-related disease characterized by reduced bone mass and microstructure deterioration, leading to increased risk of bone fragility fractures. Osteoporosis is a worldwide major health care problem and there is
Externí odkaz:
https://doaj.org/article/b9b971464f264e33a46e8edff43f2946
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 2, Pp 189-202 (2020)
Abstract Cultured human bone marrow stromal (mesenchymal) stem cells (hBM‐MSCs) are heterogenous cell populations exhibiting variable biological properties. Quantitative high‐content imaging technology allows identification of morphological marke
Externí odkaz:
https://doaj.org/article/13ac941d282442f59a7fa8848cc52f4d
Autor:
Thorben Sauer, Giulia Facchinetti, Michael Kohl, Justyna M. Kowal, Svitlana Rozanova, Julia Horn, Hagen Schmal, Ivo Kwee, Arndt-Peter Schulz, Sonja Hartwig, Moustapha Kassem, Jens K. Habermann, Timo Gemoll
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2568 (2022)
Mesenchymal stem cells (MSCs) gain an increasing focus in the field of regenerative medicine due to their differentiation abilities into chondrocytes, adipocytes, and osteoblastic cells. However, it is apparent that the transformation processes are e
Externí odkaz:
https://doaj.org/article/6ad5eb6590ee4ebe9f2fa93bb3d91a95
Autor:
Hagen Schmal, Justyna M. Kowal, Moustapha Kassem, Michael Seidenstuecker, Anke Bernstein, Katharina Böttiger, Tanshiyue Xiong, Norbert P. Südkamp, Eva J. Kubosch
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Known problems of the autologous chondrocyte implantation motivate the search for cellular alternatives. The aim of the study was to test the potential of synovium-derived stem cells (SMSC) to regenerate cartilage using a matrix-associated implantati
Externí odkaz:
https://doaj.org/article/8ba57b335fee4dd9979b0b271e9d68c0
Autor:
Florence Figeac, Michaela Tencerova, Dalia Ali, Thomas L Andersen, Dan Rémi Christiansen Appadoo, Greet Kerckhofs, Nicholas Ditzel, Justyna M Kowal, Alexander Rauch, Moustapha Kassem
Publikováno v:
Stem Cells, Vol.-, no.-, p.-(2022)
Figeac, F, Tencerova, M, Ali, D, Andersen, T L, Appadoo, D R C, Kerckhofs, G, Ditzel, N, Kowal, J M, Rauch, A & Kassem, M 2022, ' Impaired bone fracture healing in type 2 diabetes is caused by defective functions of skeletal progenitor cells ', Stem Cells, vol. 40, no. 2, pp. 149-164 . https://doi.org/10.1093/stmcls/sxab011
Figeac, F, Tencerova, M, Ali, D, Andersen, T L, Appadoo, D R C, Kerckhofs, G, Ditzel, N, Kowal, J M, Rauch, A & Kassem, M 2022, ' Impaired Bone Fracture Healing in Type 2 Diabetes Is Caused by Defective Functions of Skeletal Progenitor Cells ', Stem Cells, vol. 40, no. 2, pp. 149-164 . https://doi.org/10.1093/stmcls/sxab011
Figeac, F, Tencerova, M, Ali, D, Andersen, T L, Appadoo, D R C, Kerckhofs, G, Ditzel, N, Kowal, J M, Rauch, A & Kassem, M 2022, ' Impaired bone fracture healing in type 2 diabetes is caused by defective functions of skeletal progenitor cells ', Stem Cells, vol. 40, no. 2, pp. 149-164 . https://doi.org/10.1093/stmcls/sxab011
Figeac, F, Tencerova, M, Ali, D, Andersen, T L, Appadoo, D R C, Kerckhofs, G, Ditzel, N, Kowal, J M, Rauch, A & Kassem, M 2022, ' Impaired Bone Fracture Healing in Type 2 Diabetes Is Caused by Defective Functions of Skeletal Progenitor Cells ', Stem Cells, vol. 40, no. 2, pp. 149-164 . https://doi.org/10.1093/stmcls/sxab011
The mechanisms of obesity and type 2 diabetes (T2D)-associated impaired fracture healing are poorly studied. In a murine model of T2D reflecting both hyperinsulinemia induced by high fat diet (HFD) and insulinopenia induced by treatment with streptoz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0215a2acb0b5176d9b58439488b3d34a
https://hdl.handle.net/2078.1/257948
https://hdl.handle.net/2078.1/257948
Publikováno v:
Kowal, J M, Schmal, H, Halekoh, U, Hjelmborg, J B & Kassem, M 2020, ' Single-cell high content imaging parameters predict functional phenotype of cultured human bone marrow stromal stem cells ', Stem Cells Translational Medicine, vol. 9, no. 2, pp. 189-202 . https://doi.org/10.1002/sctm.19-0171
Stem Cells Translational Medicine, Vol 9, Iss 2, Pp 189-202 (2020)
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 9, Iss 2, Pp 189-202 (2020)
Stem Cells Translational Medicine
Cultured human bone marrow stromal (mesenchymal) stem cells (hBM-MSCs) are heterogenous cell populations exhibiting variable biological properties. Quantitative high-content imaging technology allows identification of morphological markers at a singl
Autor:
Florence Figeac, Torben Barington, Dalia Ali, Sören Möller, Hagen Schmal, Justyna M. Kowal, Moustapha Kassem
Publikováno v:
Kowal, J M, Möller, S, Ali, D, Figeac, F, Barington, T, Schmal, H & Kassem, M 2021, ' Identification of a clinical signature predictive of differentiation fate of human bone marrow stromal cells ', Stem Cell Research and Therapy, vol. 12, 265 . https://doi.org/10.1186/s13287-021-02338-1
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Background Transplantation of human bone marrow stromal cells (hBMSCs) is a promising therapy for bone regeneration due to their ability to differentiate into bone forming osteoblastic cells. However, transplanted hBMSCs exhibit variable capacity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbc397ae8a85af186581bc10871f12b
https://findresearcher.sdu.dk:8443/ws/files/182567836/s13287_021_02338_1_1_.pdf
https://findresearcher.sdu.dk:8443/ws/files/182567836/s13287_021_02338_1_1_.pdf
Autor:
Nicholas Ditzel, Radhakrishnan Vishnubalaji, Meshail Okla, Abdullah Aldahmash, Musaad Alfayez, Nehad M. Alajez, Sara Abuelreich, Dalia Ali, Justyna M. Kowal, Rimi Hamam, Paula Fernandez-Guerra, Moustapha Kassem
Publikováno v:
Ali, D, Abuelreich, S, Vishnubalaji, R, Ditzel, N, Okla, M, Fernandez-Guerra, P, Kowal, J M, Hamam, R, Alfayez, M, Aldahmash, A, Kassem, M & AlAjez, N 2021, ' Apigenin and rutaecarpine target cellular senescence to prevent aging-bone phenotype in human mesenchymal skeletal stem cells ', Free Radical Biology and Medicine, vol. 165, no. Suppl. 1, pp. 32 . https://doi.org/10.1016/j.freeradbiomed.2020.12.341
Autor:
Kaikai Shi, Weimin Qiu, Michaela Tencerova, Louise Himmelstrup Dreyer Nielsen, Li Chen, Justyna M. Kowal, Florence Figeac, Alexander Rauch, Nicholas Ditzel, Thomas Levin Andersen, Moustapha Kassem
Publikováno v:
Chen, L, Shi, K, Himmelstrup Dreyer Nielsen, L, Ditzel, N, Qiu, W, Tencerova, M, Figeac, F, Levin Andersen, T, Kowal, J, Rauch, A & Kassem, M 2020, ' KIAA1199 (CEMIP), a novel secreted factor from bone and bone marrow influences body composition and metabolism by regulating bone and fat ', Bone Reports, vol. 13, no. Suppl., PLO08 . https://doi.org/10.1016/j.bonr.2020.100328
Bone Reports, Vol 13, Iss, Pp 100328-(2020)
Bone Reports, Vol 13, Iss, Pp 100328-(2020)
Autor:
Eva Johanna Kubosch, Norbert P. Südkamp, Moustapha Kassem, Anke Bernstein, Hagen Schmal, Justyna M. Kowal, Katharina Böttiger, Michael Seidenstuecker, Tanshiyue Xiong
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2018 (2018)
Schmal, H, Kowal, J M, Kassem, M, Seidenstuecker, M, Bernstein, A, Böttiger, K, Xiong, T, Südkamp, N P & Kubosch, E J 2018, ' Comparison of Regenerative Tissue Quality following Matrix-Associated Cell Implantation Using Amplified Chondrocytes Compared to Synovium-Derived Stem Cells in a Rabbit Model for Cartilage Lesions ', Stem Cells International, vol. 2018, 4142031 . https://doi.org/10.1155/2018/4142031
Stem Cells International, Vol 2018 (2018)
Schmal, H, Kowal, J M, Kassem, M, Seidenstuecker, M, Bernstein, A, Böttiger, K, Xiong, T, Südkamp, N P & Kubosch, E J 2018, ' Comparison of Regenerative Tissue Quality following Matrix-Associated Cell Implantation Using Amplified Chondrocytes Compared to Synovium-Derived Stem Cells in a Rabbit Model for Cartilage Lesions ', Stem Cells International, vol. 2018, 4142031 . https://doi.org/10.1155/2018/4142031
Known problems of the autologous chondrocyte implantation motivate the search for cellular alternatives. The aim of the study was to test the potential of synovium-derived stem cells (SMSC) to regenerate cartilage using a matrix-associated implantati