Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Justyna Janikiewicz"'
Autor:
Aneta M. Dobosz, Justyna Janikiewicz, Ewelina Krogulec, Anna Dziewulska, Anna Ajduk, Marcin Szpila, Hanna Nieznańska, Andrzej A. Szczepankiewicz, Dorota Wypych, Agnieszka Dobrzyn
Publikováno v:
Molecular Metabolism, Vol 67, Iss , Pp 101659- (2023)
Abnormalities that characterize the pathophysiology of type 2 diabetes (T2D) include deficiencies of β-cells and the expansion of α-cells in pancreatic islets, manifested by lower insulin release and glucagon oversecretion. The molecular mechanisms
Externí odkaz:
https://doaj.org/article/93b47b0cfaee40919c316cd1cf33440e
Autor:
Ricardo Amorim, Inês C.M. Simões, José Teixeira, Fernando Cagide, Yaiza Potes, Pedro Soares, Adriana Carvalho, Ludgero C. Tavares, Sofia Benfeito, Susana P. Pereira, Rui F. Simões, Agnieszka Karkucinska-Wieckowska, Ivan Viegas, Sylwia Szymanska, Michał Dąbrowski, Justyna Janikiewicz, Teresa Cunha-Oliveira, Agnieszka Dobrzyń, John G. Jones, Fernanda Borges, Mariusz R. Wieckowski, Paulo J. Oliveira
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102400- (2022)
Non-alcoholic fatty liver disease (NAFLD) is a health concern affecting 24% of the population worldwide. Although the pathophysiologic mechanisms underlying disease are not fully clarified, mitochondrial dysfunction and oxidative stress are key playe
Externí odkaz:
https://doaj.org/article/f512c15d747348f8a5a50917b0e4613a
Autor:
Ines C. M. Simoes, Agnieszka Karkucinska-Wieckowska, Justyna Janikiewicz, Sylwia Szymanska, Maciej Pronicki, Pawel Dobrzyn, Michal Dabrowski, Agnieszka Dobrzyn, Paulo J. Oliveira, Hans Zischka, Yaiza Potes, Mariusz R. Wieckowski
Publikováno v:
Antioxidants, Vol 9, Iss 10, p 995 (2020)
Nonalcoholic fatty liver disease (NAFLD) is characterized by the development of steatosis, which can ultimately compromise liver function. Mitochondria are key players in obesity-induced metabolic disorders; however, the distinct role of hypercaloric
Externí odkaz:
https://doaj.org/article/19864496d3dd43d88c771bc5876e8caf
Autor:
Justyna Janikiewicz, Katarzyna Hanzelka, Anna Dziewulska, Kamil Kozinski, Pawel Dobrzyn, Tytus Bernas, Agnieszka Dobrzyn
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 10, Pp 1901-1911 (2015)
Autophagy is indispensable for the proper architecture and flawless functioning of pancreatic β-cells. A growing body of evidence indicates reciprocal communication between autophagic pathways, apoptosis, and intracellular lipids. The way in which e
Externí odkaz:
https://doaj.org/article/887b0013495349b493474a9c2f99e73e
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114117 (2014)
Translation elongation is the stage of protein synthesis in which the translation factor eEF1A plays a pivotal role that is dependent on GTP exchange. In vertebrates, eEF1A can exist as two separately encoded tissue-specific isoforms, eEF1A1, which i
Externí odkaz:
https://doaj.org/article/399f15eae606466e833adbda313209e6
Autor:
Gabriela Traczyk, Anna Świątkowska, Aneta Hromada-Judycka, Justyna Janikiewicz, Katarzyna Kwiatkowska
Publikováno v:
The international journal of biochemistrycell biology. 152
Diacylglycerol kinase-ε (DGKε) phosphorylates DAG to phosphatidic acid with unique specificity toward 18:0/20:4 DAG (SAG). SAG is a typical backbone of phosphatidylinositol and its derivatives, therefore DGKε activity is crucial for the turnover o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5329782867113d019a34c4cd8c8e43b
https://pubmed.ncbi.nlm.nih.gov/36113832
https://pubmed.ncbi.nlm.nih.gov/36113832
Autor:
Beata Małachowska, Justyna Janikiewicz, Karolina Pietrowska, Krystyna Wyka, Joanna Madzio, Kamila Wypyszczak, Marcin Tkaczyk, Sławomir Chrul, Rafał Zwiech, Anna Hogendorf, Maciej T. Małecki, Maciej Borowiec, Adam Krętowski, Wojciech Młynarski, Agnieszka Dobrzyń, Michał Ciborowski, Wojciech Fendler
Publikováno v:
Metabolomics. 18
Introduction Patients with hepatocyte nuclear factor-1 beta (HNF1B) mutations present a variable phenotype with two main symptoms: maturity onset diabetes of the young (MODY) and polycystic kidney disease (PKD). Objectives Identification of serum met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01556af89443d5ff09098eb8b48f14f
https://doi.org/10.1007/s11306-022-01873-z
https://doi.org/10.1007/s11306-022-01873-z
Publikováno v:
Postępy Biochemii. 64:166-174
Epidemia otyłości i cukrzycy typu 2 stanowi jedno z największych wyzwań współczesnych nauk biomedycznych. Etiologię cukrzycy typu 2 determinuje współistnienie dwóch stanów patofizjologicznych: insulinooporności tkanek obwodowych oraz dysf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b2efa12874c9d41cea9d0ecb404075e
https://doi.org/10.18388/pb.2018_127
https://doi.org/10.18388/pb.2018_127
Autor:
Kamil Zukowski, Zbigniew Brzozka, Agnieszka Dobrzyn, Elzbieta Jastrzebska, Justyna Janikiewicz, Patrycja Sokolowska
Publikováno v:
Biosensorsbioelectronics. 183
Type 2 diabetes is currently one of the most common metabolic diseases, affecting all ages worldwide. As the incidence of type 2 diabetes increases, a growing number of studies focus on islets of Langerhans. A three-dimensional research model that ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e6635be836578744ac1e88a14d9c07
https://pubmed.ncbi.nlm.nih.gov/33845292
https://pubmed.ncbi.nlm.nih.gov/33845292