Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Justyna Fert-Bober"'
Autor:
Alia Sadiq, Justyna Fert-Bober
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117579- (2024)
Background: Dilated cardiomyopathy (DCM) is characterized by enlarged, weakened heart ventricles due to chronic fibrosis. Dysfunctional senescent myofibroblasts and excessive citrullination have been implicated in fibrotic diseases. Peptidylarginine
Externí odkaz:
https://doaj.org/article/42708ba50a6d4d009ab40427f3ef2026
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115443- (2023)
Background: Cardiac fibrosis contributes to end-stage extracellular matrix remodeling and heart failure (HF). Cardiac fibroblasts (CFs) differentiate into myofibroblasts (myoFbs) to preserve the structural integrity of the heart; however, the molecul
Externí odkaz:
https://doaj.org/article/11e6a592fad043fc97678918e3371c52
Autor:
Sandy Joung, Brittany Weber, Min Wu, Yunxian Liu, Amber B. Tang, Matthew Driver, Sarah Sternbach, Timothy Wynter, Amy Hoang, Denisse Barajas, Yu Hung Kao, Briana Khuu, Michelle Bravo, Hibah Masoom, Teresa Tran, Nancy Sun, Patrick G. Botting, Brian L. Claggett, John C. Prostko, Edwin C. Frias, James L. Stewart, Jackie Robertson, Alan C. Kwan, Mariam Torossian, Isabel Pedraza, Carina Sterling, Caroline Goldzweig, Jillian Oft, Rachel Zabner, Justyna Fert-Bober, Joseph E. Ebinger, Kimia Sobhani, Susan Cheng, Catherine N. Le
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Individuals with post-acute sequelae of COVID (PASC) may have a persistence in immune activation that differentiates them from individuals who have recovered from COVID without clinical sequelae. To investigate how humoral immune
Externí odkaz:
https://doaj.org/article/97c08f464a454822a50a05680cec2ebe
Autor:
Aneta Stachowicz, Rakhi Pandey, Niveda Sundararaman, Vidya Venkatraman, Jennifer E. Van Eyk, Justyna Fert-Bober
Publikováno v:
Journal of Inflammation, Vol 19, Iss 1, Pp 1-16 (2022)
Abstract Background Macrophages are effector cells of the innate immune system that undergo phenotypical changes in response to organ injury and repair. These cells are most often classified as proinflammatory M1 and anti-inflammatory M2 macrophages.
Externí odkaz:
https://doaj.org/article/a99db7d8ce3849d4b6f999ff971e8f05
Autor:
Yunxian Liu, Joseph E. Ebinger, Rowann Mostafa, Petra Budde, Jana Gajewski, Brian Walker, Sandy Joung, Min Wu, Manuel Bräutigam, Franziska Hesping, Elena Rupieper, Ann-Sophie Schubert, Hans-Dieter Zucht, Jonathan Braun, Gil Y. Melmed, Kimia Sobhani, Moshe Arditi, Jennifer E. Van Eyk, Susan Cheng, Justyna Fert-Bober
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Pronounced sex differences in the susceptibility and response to SARS-CoV-2 infection remain poorly understood. Emerging evidence has highlighted the potential importance of autoimmune activation in modulating the acute response a
Externí odkaz:
https://doaj.org/article/7c3f66e3e6b044f8864813e5e1a63987
Autor:
Brian Claggett, Sonia Sharma, Min Wu, Peter Chen, Gil Y Melmed, Nancy Sun, Susan Cheng, Joseph E Ebinger, Matthew Driver, Dermot P B McGovern, Kimia Sobhani, Mohit Jain, Sandy Joung, Yunxian Liu, Brittany Weber, Patrick G Botting, Yu Hung Kao, Briana Khuu, Timothy Wynter, Trevor-Trung Nguyen, Mona Alotaibi, John C Prostko, Edwin C Frias, James L Stewart, Helen S Goodridge, Stanley C Jordan, Justyna Fert-Bober, Jennifer E Van Eyk, Margo B Minissian, Moshe Arditi, Jonathan G Braun
Publikováno v:
BMJ Open, Vol 12, Iss 5 (2022)
Objectives We sought to understand the demographic and clinical factors associated with variations in longitudinal antibody response following completion of two-dose regiment of BNT162b2 vaccination.Design This study is a 10-month longitudinal cohort
Externí odkaz:
https://doaj.org/article/8780247aa4eb4c398b2d4cf8d46d9331
Autor:
Niveda Sundararaman, Archana Bhat, Vidya Venkatraman, Aleksandra Binek, Zachary Dwight, Nethika R. Ariyasinghe, Sean Escopete, Sandy Y. Joung, Susan Cheng, Sarah J. Parker, Justyna Fert-Bober, Jennifer E. Van Eyk
Publikováno v:
J Proteome Res
Recent surges in large-scale mass spectrometry (MS)-based proteomics studies demand a concurrent rise in methods to facilitate reliable and reproducible data analysis. Quantification of proteins in MS analysis can be affected by variations in technic
Publikováno v:
Expert Review of Proteomics. 18:1059-1071
Arginine deimination (citrullination) is a post-translational modification catalyzed by a family of peptidyl arginine deiminase (PAD) enzymes. Cell-based functional studies and animal models have manifested the key role of PADs in various cardiovascu
Autor:
Angela McArdle, Kirstin E Washington, Alejandro Rivas, Danica-Mae Manalo, Jennifer E. Van Eyk, Aleksandra Binek, Matthew Ayres, Connor Phebus, Justyna Fert-Bober, Rakhi Pandey, Koen Raedschelders, Blandine Chazarin Orgel
Publikováno v:
Journal of Proteome Research
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible coronavirus responsible for the pandemic coronavirus disease 2019 (COVID-19), which has had a devastating impact on society. Here, we summarize proteomic research
Autor:
Marwa Kaisey, Ghazal Lashgari, Justyna Fert-Bober, Daniel Ontaneda, Andrew J. Solomon, Nancy L. Sicotte
Publikováno v:
Current neurology and neuroscience reportsPapers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance. 22(10)
For many patients, the multiple sclerosis (MS) diagnostic process can be lengthy, costly, and fraught with error. Recent research aims to address the unmet need for an accurate and simple diagnostic process through discovery of novel diagnostic bioma