Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Justyna Czapla"'
Autor:
Ewelina Pilny, Justyna Czapla, Alina Drzyzga, Ryszard Smolarczyk, Sybilla Matuszczak, Magdalena Jarosz-Biej, Łukasz Krakowczyk, Tomasz Cichoń
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Background Adipose-derived stromal cells (ADSCs) demonstrate ability to promote tissue healing and down-regulate excessive inflammation. ADSCs have been used to treat critical limb ischemia in preclinical and clinical trials, but still, ther
Externí odkaz:
https://doaj.org/article/729fd186e8634bb1a04a6c16eb76cb00
Autor:
Justyna Czapla, Alina Drzyzga, Sybilla Matuszczak, Tomasz Cichoń, Marek Rusin, Magdalena Jarosz-Biej, Ewelina Pilny, Ryszard Smolarczyk
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionTargeting tumor vasculature is an efficient weapon to fight against cancer; however, activation of alternative pathways to rebuild the disrupted vasculature leads to rapid tumor regrowth. Immunotherapy that exploits host immune cells to e
Externí odkaz:
https://doaj.org/article/f9049cc6dd234f21be06968ce1421094
Autor:
Natalia Kułach, Ewelina Pilny, Tomasz Cichoń, Justyna Czapla, Magdalena Jarosz-Biej, Marek Rusin, Alina Drzyzga, Sybilla Matuszczak, Stanisław Szala, Ryszard Smolarczyk
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Due to immunosuppressive properties and confirmed tropism towards cancer cells mesenchymal stromal cells (MSC) have been used in many trials. In our study we used these cells as carriers of IL-12 in the treatment of mice with primary and met
Externí odkaz:
https://doaj.org/article/bcd4d466f3a84e96830b0f5ae3e9063f
Autor:
Sybilla Matuszczak, Krzysztof Szczepanik, Aleksandra Grządziel, Alina Drzyzga, Tomasz Cichoń, Justyna Czapla, Ewelina Pilny, Ryszard Smolarczyk
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1773 (2023)
Radiotherapy (RT) is one of the main treatments for head and neck squamous cell carcinomas (HNSCCs). Unfortunately, radioresistance is observed in many cases of HNSCCs. The effectiveness of RT depends on both the direct effect inducing cell death and
Externí odkaz:
https://doaj.org/article/d5d90e6bd73c400a86b79161a2370229
Autor:
Sandra Charvátová, Benjamin Motais, Justyna Czapla, Tomasz Cichoń, Ryszard Smolarczyk, Zuzana Walek, Sebastian Giebel, Roman Hájek, Juli R. Bagó
Publikováno v:
Cells, Vol 12, Iss 3, p 448 (2023)
Myeloma bone disease (MBD) is one of the major complications in multiple myeloma (MM)—the second most frequent hematologic malignancy. It is characterized by the formation of bone lesions due to the local action of proliferating MM cells, and to da
Externí odkaz:
https://doaj.org/article/4c28c9e36fa64929a560eb1aba01bcc8
Autor:
Beata Biesaga, Ryszard Smolarczyk, Anna Mucha-Małecka, Justyna Czapla, Janusz Ryś, Krzysztof Małecki
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2538 (2022)
Infection with HPV16 in cancers of the oral cavity (OCSCC) and oropharynx (OPSCC) is, today, an important etiological and prognostic factor. Patients with HPV-positive OPSCC have a better prognosis than uninfected patients. However, in over 40% of th
Externí odkaz:
https://doaj.org/article/df06f1405a8244afbb49a2c6df2f439a
Autor:
Justyna Czapla, Sybilla Matuszczak, Klaudia Kulik, Ewa Wiśniewska, Ewelina Pilny, Magdalena Jarosz-Biej, Ryszard Smolarczyk, Tomasz Sirek, Michał Oskar Zembala, Marian Zembala, Stanisław Szala, Tomasz Cichoń
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-11 (2019)
Abstract Background Adipose tissue-derived mesenchymal stromal cells (ASCs) have been shown to exhibit some promising properties of their use in regenerative medicine as advanced therapy medicinal products (ATMP). However, different sources of their
Externí odkaz:
https://doaj.org/article/f32f1a60b8e9465a8e8198df4e296c46
Autor:
Benjamin Motais, Sandra Charvátová, Zuzana Walek, Matouš Hrdinka, Ryszard Smolarczyk, Tomasz Cichoń, Justyna Czapla, Sebastian Giebel, Michal Šimíček, Tomáš Jelínek, Tereza Ševčíková, Jiří Sobotka, Zdeněk Kořístek, Roman Hájek, Juli R. Bagó
Publikováno v:
Cells, Vol 10, Iss 5, p 967 (2021)
Cellular immunotherapy is becoming a new pillar in cancer treatment after recent striking results in different clinical trials with chimeric antigen receptor T cells. However, this innovative therapy is not exempt from challenges such as off-tumor to
Externí odkaz:
https://doaj.org/article/f6a2e2b59cd641978a04a955a739f7f8
Autor:
Magdalena Jarosz-Biej, Natalia Kamińska, Sybilla Matuszczak, Tomasz Cichoń, Jolanta Pamuła-Piłat, Justyna Czapla, Ryszard Smolarczyk, Daria Skwarzyńska, Klaudia Kulik, Stanisław Szala
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191012 (2018)
Tumor-associated macrophages (TAMs) play a significant role in at least two key processes underlying neoplastic progression: angiogenesis and immune surveillance. TAMs phenotypic changes play important role in tumor vessel abnormalization/ normalizat
Externí odkaz:
https://doaj.org/article/a7393c4f0cf1461f933726948853a312
Autor:
Justyna Czapla, Sybilla Matuszczak, Ewa Wiśniewska, Magdalena Jarosz-Biej, Ryszard Smolarczyk, Tomasz Cichoń, Magdalena Głowala-Kosińska, Joanna Śliwka, Marcin Garbacz, Mateusz Szczypior, Tomasz Jaźwiec, Agnieszka Langrzyk, Michał Zembala, Stanisław Szala
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158745 (2016)
The aim of the present study was to isolate mesenchymal stromal cells (MSC) with CD105+CD34- phenotype from human hearts, and to investigate their therapeutic potential in a mouse model of hindlimb ischemia and myocardial infarction (MI). The study a
Externí odkaz:
https://doaj.org/article/6f8d197348ba40f5b0a3dfffff7f8dfc