Zobrazeno 1 - 10
of 514
pro vyhledávání: '"Justus, Duyster"'
Autor:
Julia C. Kuehn, Patrick Metzger, Nicolas Neidert, Uta Matysiak, Linda Gräßel, Ulrike Philipp, Sabine Bleul, Thomas Pauli, Julia Falkenstein, Henriette Bertemes, Stepan Cysar, Maria Elena Hess, Anna Verena Frey, Jesús Duque-Afonso, Elisabeth Schorb, Marcia Machein, Jürgen Beck, Oliver Schnell, Nikolas von Bubnoff, Anna L. Illert, Christoph Peters, Tilman Brummer, Marco Prinz, Cornelius Miething, Heiko Becker, Silke Lassmann, Martin Werner, Melanie Börries, Justus Duyster, Dieter H. Heiland, Roman Sankowski, Florian Scherer
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract Despite major advances in molecular profiling and classification of primary brain tumors, personalized treatment remains limited for most patients. Here, we explored the feasibility of individual molecular profiling and the efficacy of bioma
Externí odkaz:
https://doaj.org/article/1dc07143d8964d58a48d87e8eab4e848
Autor:
Sivahari P. Gorantla, Gerin Prince, Jasmin Osius, Dhurvas Chandrasekaran Dinesh, Vijay Boddu, Justus Duyster, Nikolas von Bubnoff
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundRuxolitinib has been approved by the US FDA for the treatment of myeloproliferative neoplasms such as polycythemia vera and primary myelofibrosis. Ruxolitinib will remain a main stay in the treatment of MPN patients due to its effective the
Externí odkaz:
https://doaj.org/article/d15f0a582d1444fa955de4dbeaac8a8c
Autor:
Sivahari Prasad Gorantla, Tony Andreas Mueller, Corinna Albers‐Leischner, Martina Rudelius, Nikolas vonBubnoff, Justus Duyster
Publikováno v:
Molecular Oncology, Vol 18, Iss 2, Pp 415-430 (2024)
Tyrosine‐protein kinase (janus kinase; JAK)–signal transducer and activator of transcription (STAT) signaling plays a pivotal role in the development of myeloproliferative neoplasms (MPNs). Treatment with the potent JAK1/JAK2‐specific inhibitor
Externí odkaz:
https://doaj.org/article/7d73443b165c4267b410f643f968e47e
Autor:
Miriam Mozaffari Jovein, Gabriele Ihorst, Jesús Duque-Afonso, Ralph Wäsch, Hartmut Bertz, Claudia Wehr, Justus Duyster, Robert Zeiser, Jürgen Finke, Florian Scherer
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Primary induction failure (PIF) in acute myeloid leukemia (AML) patients is associated with poor outcome, with allogeneic hematopoietic stem cell transplantation (HCT) being the sole curative therapeutic option. Here, we retrospectively eval
Externí odkaz:
https://doaj.org/article/b0c4ddf6437348259a83d0ec04d80321
Dieses Buch ist eine Open-Access-Publikation unter einer Creative Commons Attribution International License (CC BY 4.0). Bewährt und einfach zu handhaben: praxisorientierte Sammlung von Chemotherapie-Protokollen zur Behandlung von Tumorpatienten mit
Autor:
Nora Rebeka Javorniczky, Olga Grishina, Inga Hund, Milena Pantic, Dietmar Pfeifer, Claudia Schmoor, Johanna Thomas, Justus Duyster, Heiko Becker, Michael Lübbert
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-5 (2023)
Abstract Elderly patients with AML ineligible for induction have a dismal prognosis; hence disease stabilization is a primary treatment goal. This case of a 75-year-old patient with secondary AML receiving the combination of decitabine and ATRA (with
Externí odkaz:
https://doaj.org/article/6085df4c75ec4101b2942e2480228aaa
Autor:
Ruth Meier, Gabriele Greve, Dennis Zimmer, Helena Bresser, Bettina Berberich, Ralitsa Langova, Julia Stomper, Anne Rubarth, Lars Feuerbach, Daniel B. Lipka, Joschka Hey, Björn Grüning, Benedikt Brors, Justus Duyster, Christoph Plass, Heiko Becker, Michael Lübbert
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 8, Pp 1-13 (2022)
Abstract The prognosis of AML patients with adverse genetics, such as a complex, monosomal karyotype and TP53 lesions, is still dismal even with standard chemotherapy. DNA-hypomethylating agent monotherapy induces an encouraging response rate in thes
Externí odkaz:
https://doaj.org/article/3459f942a8ff4fc4b157fd33b7c8b1eb
Dieses Buch ist eine Open-Access-Publikation unter einer CC BY-NC 2.5 Lizenz.Einfach handhabbare und praxisorientierte Sammlung von Chemotherapie-Protokollen zur Behandlung von Tumorpatienten mit soliden und hämatologischen Erkrankungen. Wie gewohnt
Autor:
Silvia Waldeck, Jan Mitschke, Sebastian Wiesemann, Michael Rassner, Geoffroy Andrieux, Max Deuter, Jurik Mutter, Anne‐Marie Lüchtenborg, Daniel Kottmann, Laurin Titze, Christoph Zeisel, Martina Jolic, Ulrike Philipp, Silke Lassmann, Peter Bronsert, Christine Greil, Justyna Rawluk, Heiko Becker, Lisa Isbell, Alexandra Müller, Soroush Doostkam, Bernward Passlick, Melanie Börries, Justus Duyster, Julius Wehrle, Florian Scherer, Nikolas von Bubnoff
Publikováno v:
Molecular Oncology, Vol 16, Iss 2, Pp 527-537 (2022)
Circulating tumor DNA (ctDNA) has demonstrated great potential as a noninvasive biomarker to assess minimal residual disease (MRD) and profile tumor genotypes in patients with non‐small‐cell lung cancer (NSCLC). However, little is known about its
Externí odkaz:
https://doaj.org/article/4399d10b1bd049f3a353a6cfadf469f6
Autor:
Christoph Rummelt, Olga Grishina, Claudia Schmoor, Martina Crysandt, Michael Heuser, Katharina S. Götze, Richard F. Schlenk, Konstanze Döhner, Helmut R. Salih, Gerhard Heil, Carsten Müller-Tidow, Wolfram Brugger, Andrea Kündgen, Maike de Wit, Aristoteles Giagounidis, Sebastian Scholl, Andreas Neubauer, Jürgen Krauter, Gesine Bug, Haifa Kathrin Al-Ali, Ralph Wäsch, Heiko Becker, Annette M. May, Justus Duyster, Björn Hackanson, Arnold Ganser, Hartmut Döhner, Michael Lübbert
Publikováno v:
Haematologica, Vol 108, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/3448ad0c720c4bd583057eb97a440fb5