Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Justine Y.Q. Lai"'
Autor:
Hiroki Wada, Tony Raynham, Rebekah E. Beevers, Jeremy Major, Jess Taylor, Neil Grimster, David W. Walker, Parminder Kaur Ruprah, Svenja Burckhardt, Hannah Fiona Sore, James Nally, Alison Reid, Steven P. Langston, Andrew H. Henry, Helen J. Payne, Yvonne Ferguson, John C Reader, Eva Figueroa, Michael Shaw, Abid Masood, Nawaz Mohammed Khan, Valérie Reader, Lloyd J. Payne, Kerry Jenkins, Stephen Thompson, Ruth Adams, Matthew Stirling, Richard J. Boyce, Adam C. Talbot, Gilles Raphy, Jones Mark, Robert Judkins, James M. Cobb, Justine Y.Q. Lai
Publikováno v:
Medicinal Research Reviews. 25:310-330
This work describes the preparation of approximately 13,000 compounds for rapid identification of hits in high-throughput screening (HTS). These compounds were designed as potential serine/threonine or tyrosine kinase inhibitors. The library consists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c2cfd46838ec84ce2d3ca8b3d9e0bd
https://doi.org/10.1002/med.20026
https://doi.org/10.1002/med.20026
Autor:
Helen J. Payne, James M. Cobb, Justine Y.Q. Lai, Neil Grimster, Lloyd J. Payne, Tony Raynham, Nawaz Mohammed Khan, Jess Taylor
Publikováno v:
Tetrahedron Letters. 43:7557-7560
The synthesis of 1,2,4-trisubstituted imidazoles was demonstrated via the solid phase synthesis of N -alkyl- N -(β-keto)amides using a carbazate linker. The approach enabled the assembly of a diverse number of N -alkyl- N -(β-keto)amide intermediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86443dadd9d139a5eefda6fcc2e72cd7
https://doi.org/10.1016/s0040-4039(02)01810-5
https://doi.org/10.1016/s0040-4039(02)01810-5
Publikováno v:
Tetrahedron Letters. 41:271-274
The synthesis of quinuclidine enamine N -oxide and quinuclidine enamine borane complex is described. Selective deprotonation of the double bond allows the direct functionalisation at the α-position with a range of electrophiles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4de8ea5b212d29fd1c4123d9ab14b4b8
https://doi.org/10.1016/s0040-4039(99)02033-x
https://doi.org/10.1016/s0040-4039(99)02033-x