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of 6
pro vyhledávání: '"Justine Vanhevel"'
Autor:
Stefanie Doms, Lieve Verlinden, Iris Janssens, Justine Vanhevel, Roy Eerlings, René Houtman, Shigeaki Kato, Chantal Mathieu, Brigitte Decallonne, Geert Carmeliet, Annemieke Verstuyf
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract The vitamin D receptor (VDR) plays a critical role in the regulation of mineral and bone homeostasis. Upon binding of 1α,25-dihydroxyvitamin D3 to the VDR, the activation function 2 (AF2) domain repositions and recruits coactivators for the
Externí odkaz:
https://doaj.org/article/f27a6b6d0cb449ae93888a4d081135ad
Autor:
Justine Vanhevel, Lieve Verlinden, Shauni Loopmans, Stefanie Doms, Iris Janssens, Sien Bevers, Steve Stegen, Hans Wildiers, Annemieke Verstuyf
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Active vitamin D3, 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], and its synthetically derived analogs possess potent anticancer properties. In breast cancer (BC) cells, 1,25(OH)2D3 blocks cell proliferation and induces apoptosis through different cell-typ
Externí odkaz:
https://doaj.org/article/f8c2d50d3b314c8eb21cb7d3f7fb7c48
Publikováno v:
Endocrine-Related Cancer. 29:R33-R55
The active form of vitamin D3, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), is primarily known as a key regulator of calcium and phosphate homeostasis. It exerts its biological functions by binding to the vitamin D receptor (VDR), a transcription factor t
Autor:
Roger Bouillon, Justine Vanhevel, Lieve Verlinden, Stefanie Doms, Pierre J. De Clercq, Annemieke Verstuyf, Iris Janssens
Bisphosphonates like risedronate inhibit osteoclast-mediated bone resorption and are therefore used in the prevention and treatment of osteoporosis. Also vitamin D3 and calcium supplementation is commonly used in the prevention or treatment of osteop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271c43e56cdd4821303bb111f5bd8c85
https://lirias.kuleuven.be/handle/123456789/633071
https://lirias.kuleuven.be/handle/123456789/633071
Autor:
Stefanie, Doms, Lieve, Verlinden, Justine, Vanhevel, Iris, Janssens, Roger, Bouillon, Pierre, De Clercq, Annemieke, Verstuyf
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 188
Bisphosphonates like risedronate inhibit osteoclast-mediated bone resorption and are therefore used in the prevention and treatment of osteoporosis. Also vitamin D
Autor:
Annemieke Verstuyf, Iris Janssens, Geert Carmeliet, Stefanie Doms, Justine Vanhevel, Lieve Verlinden
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 195:105478
The long-recognized role of the vitamin D endocrine system is to maintain stable serum calcium concentrations, which are ensured by a complex interplay between parathyroid gland, kidney, intestine, and bone. However, although VDR is expressed in oste