Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Justine R. Smith"'
Autor:
João M. Furtado, Justine R. Smith
Publikováno v:
Journal of Family Medicine and Primary Care, Vol 13, Iss 11, Pp 4815-4818 (2024)
Up to 10% of uveitis cases occur in children, with notable implications due to the risk of chronicity and vision loss. It can result from infections, autoimmune and autoinflammatory diseases, trauma, or masquerade syndromes. Primary care providers ar
Externí odkaz:
https://doaj.org/article/dad14b3620d245d1a8cfac78f4dc38e9
Autor:
Melissa K. Shields, Tiago E. Arantes, Stewart R. Lake, Rubens Belfort, Cristina Muccioli, Heloisa Nascimento, Rafael de Pinho Queiroz, Daniel V. Vasconcelos-Santos, João M. Furtado, Justine R. Smith
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Ocular syphilis is a re-emerging inflammatory eye disease with a clear gender imbalance, disproportionately affecting men. We investigated the impact of gender on the presentation, management practices and clinical outcomes of this condition
Externí odkaz:
https://doaj.org/article/ed5a4d86f2f8416a80864f5bf1ad3b4b
Autor:
Liam M. Ashander, Amanda L. Lumsden, Yuefang Ma, Alwin Chun Rong Tan, Binoy Appukuttan, Santhosh Daniel, Michael Z. Michael, Justine R. Smith
Publikováno v:
Frontiers in Drug Discovery, Vol 4 (2024)
As a key host protein involved in cellular infection by the severe acute respiratory syndrome coronavirus (SARS-CoV-2), angiotensin converting enzyme (ACE)2 is an ideal target for antiviral drugs. Manipulation of transcription provides opportunity fo
Externí odkaz:
https://doaj.org/article/69961812c22a4d75ba5b7c5364291f7d
Publikováno v:
Pathogens, Vol 13, Iss 11, p 968 (2024)
Toxoplasma gondii is an Apicomplexan parasite that is estimated to infect at least one-third of the global human population. T. gondii infection may be transmitted horizontally or vertically. The main risk factors for transmission to humans are relat
Externí odkaz:
https://doaj.org/article/711dd2532336485eaa19d8068da1f424
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Multiple studies have showed negative impact of non-infectious uveitis on quality of life (QoL). Less is understood regarding life experiences in patients with infectious uveitis. We investigated vision-related QoL in individuals who had rec
Externí odkaz:
https://doaj.org/article/5fe2c8abae6e470c997fd42158bc792f
Autor:
Alwin Chun Rong Tan, Yuefang Ma, Binoy Appukuttan, Karen Lower, Amanda L. Lumsden, Michael Z. Michael, Justine R. Smith, Liam M. Ashander
Publikováno v:
Frontiers in Ophthalmology, Vol 4 (2024)
Intercellular adhesion molecule 1 (ICAM-1) is a central cell adhesion molecule for retinal transendothelial migration of the leukocytes in non-infectious posterior uveitis. Inhibiting ICAM1 gene transcription reduces induction of ICAM-1 in inflamed r
Externí odkaz:
https://doaj.org/article/312c829ffc5e437999c2ad334b0b61ea
Autor:
Lisia Barros Ferreira, Liam M. Ashander, Binoy Appukuttan, Yuefang Ma, Keryn A. Williams, Giles Best, Justine R. Smith
Publikováno v:
Journal of Ophthalmic Inflammation and Infection, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Background Interleukin (IL)-6 is an inflammatory cytokine present in the eye during non-infectious uveitis, where it contributes to the progression of inflammation. There are two major IL-6 signaling pathways: classic signaling and trans-sig
Externí odkaz:
https://doaj.org/article/517bae752a304df58347a4ecb5a294a2
Publikováno v:
International Journal of Retina and Vitreous, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract Background To report a case of bilateral intermediate uveitis without cystoid macular edema secondary to paclitaxel therapy, and its successful management with oral corticosteroids. Case presentation A 66-year-old female developed bilateral
Externí odkaz:
https://doaj.org/article/64db556012e64017a80fdef838e6c174
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Macular edema is the pathological accumulation of fluid in the central retina. It is a complication of many retinal diseases, including diabetic retinopathy, retinal vascular occlusions and uveitis, among others. Macular edema causes decreased visual
Externí odkaz:
https://doaj.org/article/24a412a1be8c4716bc96b418e1882f2f
Autor:
Genevieve F. Oliver, Lisia Barros Ferreira, Barbara R. Vieira, Sigrid Arruda, Michelle Araújo, Jillian M. Carr, Justine R. Smith, João M. Furtado
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Toxoplasmic retinochoroiditis is a common, potentially blinding parasitic infection. We sought to define the spectrum and frequency of signs of active toxoplasmic retinochoroiditis by spectral domain optical coherence tomography (SD-OCT), an
Externí odkaz:
https://doaj.org/article/2e290504f58949b296835c55b9c82104