Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Justine P. Lu"'
Autor:
Madeline E. Kavanagh, Benjamin D. Horning, Roli Khattri, Nilotpal Roy, Justine P. Lu, Landon R. Whitby, Jaclyn C. Brannon, Albert Parker, Joel M. Chick, Christie L. Eissler, Ashley Wong, Joe L. Rodriguez, Socorro Rodiles, Kim Masuda, John R. Teijaro, Gabriel M. Simon, Matthew P. Patricelli, Benjamin F. Cravatt
The JAK family of non-receptor tyrosine kinases includes four subtypes (JAK1, JAK2, JAK3, and TYK2) and is responsible for signal transduction downstream of diverse cytokine receptors. JAK inhibitors have emerged as important therapies for immuno(onc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993a7767159730d69ddcc97d83645185
https://doi.org/10.1101/2022.01.31.478302
https://doi.org/10.1101/2022.01.31.478302
Autor:
Madeline E. Kavanagh, Benjamin D. Horning, Roli Khattri, Nilotpal Roy, Justine P. Lu, Landon R. Whitby, Elva Ye, Jaclyn C. Brannon, Albert Parker, Joel M. Chick, Christie L. Eissler, Ashley J. Wong, Joe L. Rodriguez, Socorro Rodiles, Kim Masuda, John R. Teijaro, Gabriel M. Simon, Matthew P. Patricelli, Benjamin F. Cravatt
Publikováno v:
Nature Chemical Biology. 18:1288-1288
Autor:
Justine P. Lu, Forrest A. Wright, Nicolas Dupré, Danielle A. Sliter, Richard J.H. Wojcikiewicz, Guy A. Rouleau
Publikováno v:
The Journal of biological chemistry. 290(22)
RNF170 is an endoplasmic reticulum membrane ubiquitin ligase that contributes to the ubiquitination of activated inositol 1,4,5-trisphosphate (IP3) receptors, and also, when point mutated (arginine to cysteine at position 199), causes autosomal domin
Autor:
Justine P. Lu, Richard J.H. Wojcikiewicz, Margaret M.P. Pearce, Yuan Wang, Danielle A. Sliter
Publikováno v:
The Journal of biological chemistry. 286(27)
Inositol 1,4,5-trisphosphate (IP(3)) receptors are endoplasmic reticulum membrane calcium channels that, upon activation, are degraded via the ubiquitin-proteasome pathway. While searching for novel mediators of IP(3) receptor processing, we discover