Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Justine Nuytens"'
Autor:
Eva Hulstaert, Anneleen Decock, Annelien Morlion, Celine Everaert, Kimberly Verniers, Justine Nuytens, Nele Nijs, Gary P. Schroth, Scott Kuersten, Stephen M. Gross, Pieter Mestdagh, Jo Vandesompele
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100475- (2021)
Summary: Comprehensive transcriptome analysis of extracellular RNA (exRNA) purified from human biofluids is challenging because of the low RNA concentration and compromised RNA integrity. Here, we describe an optimized workflow to (1) isolate exRNA f
Externí odkaz:
https://doaj.org/article/7bfd217891a641cf956cdf736c0d0699
Autor:
Pieter-Jan Volders, Steve Lefever, Shalina Baute, Justine Nuytens, Katrien Vanderheyden, Björn Menten, Pieter Mestdagh, Jo Vandesompele
Publikováno v:
Non-Coding RNA, Vol 4, Iss 3, p 21 (2018)
The landscape of somatic copy-number alterations (SCNAs) affecting long non-coding RNAs (lncRNAs) in human cancers remains largely unexplored. While the majority of lncRNAs remain to be functionally characterized, several have been implicated in canc
Externí odkaz:
https://doaj.org/article/514fad100a834b76b14656bf22bcbefb
Autor:
Annelien Morlion, Philippe Decruyenaere, Kathleen Schoofs, Jasper Anckaert, Justine Nuytens, Eveline Vanden Eynde, Kimberly Verniers, Celine Everaert, Fritz Offner, Jo Van Dorpe, Jo Vandesompele, Pieter Mestdagh
Circulating nucleic acids in blood plasma form an attractive resource to study human health and disease. Here, we applied mRNA capture sequencing of blood plasma cell-free RNA from 266 cancer patients and cancer-free controls (discovery n=208, 25 can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b20d8a12ebd043fb92044505b0e2e76
https://doi.org/10.1101/2023.05.24.23290388
https://doi.org/10.1101/2023.05.24.23290388
Autor:
Marieke Vromman, Jasper Anckaert, Stefania Bortoluzzi, Alessia Buratin, Chia-Ying Chen, Qinjie Chu, Trees-Juen Chuang, Roozbeh Dehghannasiri, Christoph Dieterich, Xin Dong, Paul Flicek, Enrico Gaffo, Wanjun Gu, Chunjiang He, Steve Hoffmann, Osagie Izuogu, Michael S. Jackson, Tobias Jakobi, Eric C. Lai, Justine Nuytens, Julia Salzman, Mauro Santibanez-Koref, Peter Stadler, Olivier Thas, Eveline Vanden Eynde, Kimberly Verniers, Guoxia Wen, Jakub Westholm, Li Yang, Chu-Yu Ye, Nurten Yigit, Guo-Hua Yuan, Jinyang Zhang, Fangqing Zhao, Jo Vandesompele, Pieter-Jan Volders
The detection of circular RNA molecules (circRNAs) is typically based on short-read RNA sequencing data processed by computational detection tools. During the last decade, a plethora of such tools have been developed, but a systematic comparison with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110a536623d837fc2b96c3617b91a7f2
https://hdl.handle.net/11577/3488201
https://hdl.handle.net/11577/3488201
Autor:
Vanessa Vermeirssen, Jill Deleu, Annelien Morlion, Celine Everaert, Jilke De Wilde, Jasper Anckaert, Kaat Durinck, Justine Nuytens, Muhammad Rishfi, Frank Speleman, Hanne Van Droogenbroeck, Kimberly Verniers, Maria Francesca Baietti, Maarten Albersen, Eleonora Leucci, Edward Post, Myron G Best, Tom Van Maerken, Bram De Wilde, Jo Vandesompele, Anneleen Decock
Publikováno v:
Vermeirssen, V, Deleu, J, Morlion, A, Everaert, C, De Wilde, J, Anckaert, J, Durinck, K, Nuytens, J, Rishfi, M, Speleman, F, Van Droogenbroeck, H, Verniers, K, Baietti, M F, Albersen, M, Leucci, E, Post, E, Best, M G, Van Maerken, T, De Wilde, B, Vandesompele, J & Decock, A 2022, ' Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA ', NAR Cancer, vol. 4, no. 4, zcac037 . https://doi.org/10.1093/narcan/zcac037
NAR CANCER
Ghent University Academic Bibliography
NAR Cancer, 4(4):zcac037
NAR CANCER
Ghent University Academic Bibliography
NAR Cancer, 4(4):zcac037
While cell-free DNA (cfDNA) is widely being investigated, free circulating RNA (extracellular RNA, exRNA) has the potential to improve cancer therapy response monitoring and detection due to its dynamic nature. However, it remains unclear in which bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee3e449884e4fcebdc0bb3a8278f854
https://lirias.kuleuven.be/handle/20.500.12942/708090
https://lirias.kuleuven.be/handle/20.500.12942/708090
Autor:
Jo Vandesompele, Justine Nuytens, Aart G. Jochemsen, Didier Decaudin, Fariba Nemati, Jilke De Wilde, Manuel Rodrigues, Rudy Van Coster, Eleonora Leucci, Joél Smet, Louis Delhaye, Peihua Zhao, Shanna Dewaele, Pieter Mestdagh, Jasper Anckaert, Sven Eyckerman, Katrien Vanderheyden, Eric James de Bony, Maxime Verschoore, Boel De Paepe, Jo Van Dorpe, Jean-Christophe Marine, Nurten Yigit, Eveline Vanden Eynde
Publikováno v:
Oncogene
ONCOGENE
ONCOGENE
Long non-coding RNAs (lncRNAs) can exhibit cell-type and cancer-type specific expression profiles, making them highly attractive as therapeutic targets. Pan-cancer RNA sequencing data revealed broad expression of the SAMMSON lncRNA in uveal melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2581ad7896383dcdd1dbb534b7c760
https://doi.org/10.1038/s41388-021-02006-x
https://doi.org/10.1038/s41388-021-02006-x
mTOR inhibition enhances delivery and activity of antisense oligonucleotides in uveal melanoma cells
Autor:
Sven Eyckerman, Bram Bogaert, Boel De Paepe, Shanna Dewaele, Nurten Yigit, Pieter Mestdagh, Jasper Anckaert, Justine Nuytens, Ramiro Martinez, Koen Raemdonck, Rudy Van Coster, Louis Delhaye
Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Due to a lack of effective treatments, patients with metastatic disease have a median survival time of 6-12 months. We recently demonstrated that the SAMMSON long non-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c39d5f9289b2cc4cd46b12d1d8cded18
https://doi.org/10.1101/2021.09.29.462324
https://doi.org/10.1101/2021.09.29.462324
Autor:
Eric James de Bony, Aidan P. Tay, Justine Nuytens, Steve Lefever, Tim De Meyer, Marieke Vromman, Pieter Mestdagh, Tine Goovaerts, Nandan P. Deshpande, Stephen M. Gross, Katleen De Preter, Lucia Lorenzi, Jo Vandesompele, Nele Nijs, Pieter-Jan Volders, Jørgen Kjems, Scott Kuersten, Pavel Sumazin, Francisco Avila Cobos, Wim Trypsteen, Jasper Anckaert, Katrien Vanderheyden, Govardhan Anande, Marc R. Wilkins, Ken R. Bracke, Ting-Wen Chen, Robrecht Cannoodt, Tom Taghon, Yvan Saeys, Thomas B. Hansen, Fien Gysens, Hua-Sheng Chiu, Jan Koster, Karim Vermaelen, Gary P. Schroth, Ashwin Unnikrishnan
Publikováno v:
Lorenzi, L, Chiu, H S, Avila Cobos, F, Gross, S, Volders, P J, Cannoodt, R, Nuytens, J, Vanderheyden, K, Anckaert, J, Lefever, S, Tay, A P, de Bony, E J, Trypsteen, W, Gysens, F, Vromman, M, Goovaerts, T, Hansen, T B, Kuersten, S, Nijs, N, Taghon, T, Vermaelen, K, Bracke, K R, Saeys, Y, De Meyer, T, Deshpande, N P, Anande, G, Chen, T W, Wilkins, M R, Unnikrishnan, A, De Preter, K, Kjems, J, Koster, J, Schroth, G P, Vandesompele, J, Sumazin, P & Mestdagh, P 2021, ' The RNA Atlas expands the catalog of human non-coding RNAs ', Nature Biotechnology, vol. 39, no. 11, pp. 1453-1465 . https://doi.org/10.1038/s41587-021-00936-1
Nature biotechnology, 39(11), 1453-1465. Nature Publishing Group
Nature biotechnology, 39(11), 1453-1465. Nature Publishing Group
Existing compendia of non-coding RNA (ncRNA) are incomplete, in part because they are derived almost exclusively from small and polyadenylated RNAs. Here we present a more comprehensive atlas of the human transcriptome, which includes small and polyA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28c0dc79d11cbb4d61d9ccee5d6f076
Autor:
Jo Vandesompele, Eva Hulstaert, Justine Nuytens, Nicolaas Lumen, Lau S, Pieter Mestdagh, Julia Keith, Maccaferri M, Annelien Morlion, Ponti G, Ioannis Prassas, Eleftherios P. Diamandis
A diagnostic non-invasive biomarker test for prostate cancer at an early stage, with high sensitivity and specificity, would improve diagnostic decision making. Extracellular RNAs present in seminal plasma might contain biomarker potential for the ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90c33252a5e6a6f8812ba4b20dcc916b
https://doi.org/10.1101/2021.05.11.21256306
https://doi.org/10.1101/2021.05.11.21256306
Autor:
Bert Dhondt, Gary P. Schroth, Celine Everaert, Avila Cobos F, Jasper Anckaert, Nurten Yigit, Jill Deleu, Eva Hulstaert, Van Maerken T, Vanden Eynde E, Piofczyk T, Scott Kuersten, Annelien Morlion, De Wever O, Anneleen Decock, De Wilde J, Kathleen Schoofs, Pieter Mestdagh, Kimberly Verniers, Thibaut D’huyvetter, An Hendrix, Justine Nuytens, Philippron A, Hetty Helsmoortel, Jo Vandesompele, Van Paemel R, Nele Nijs, Carolina Fierro
The use of blood-based extracellular RNA (cell-free RNA; exRNA) as clinical biomarker requires the implementation of a validated procedure for sample collection, processing, and profiling. So far, no study has systematically addressed the pre-analyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33c22152e1f08a0a56865339c2c14a4c
https://doi.org/10.1101/2021.05.11.442610
https://doi.org/10.1101/2021.05.11.442610