Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Justine M. Mucinski"'
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 5, Pp 100366- (2023)
Ceramides (CERs) are key intermediate sphingolipids implicated in contributing to mitochondrial dysfunction and the development of multiple metabolic conditions. Despite the growing evidence of CER role in disease risk, kinetic methods to measure CER
Externí odkaz:
https://doaj.org/article/b534db1adc3f4fb0b6783ce0dd43a9f6
Autor:
Justine M. Mucinski, Alisha M. Perry, Talyia M. Fordham, Alberto Diaz-Arias, Jamal A. Ibdah, R. Scott Rector, Elizabeth J. Parks
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
In vivo methods to estimate human liver mitochondrial activity are lacking and this project’s goal was to use a non-invasive breath test to quantify complete mitochondrial fat oxidation and determine how test results changed when liver disease stat
Externí odkaz:
https://doaj.org/article/a48b01b8f0d84ddf8ced6f0fa221533b
Autor:
Nhan T. Lee, Camila Manrique-Acevedo, Qiong Hu, Guido Lastra, Elizabeth J. Parks, Miriam Jacome-Sosa, Ayman H. Gaballah, Bruce D. Bartholow, Jennifer M. Anderson, Nathan C. Winn, Justine M. Mucinski, Majid M. Syed-Abdul, Alhareth Al Juboori
Publikováno v:
Alcohol. 90:45-55
Excess energy intake by spectators at a sporting event (i.e., a tailgate) might cause acute negative health effects. However, limited data exist regarding the effects of overeating and alcohol consumption on lipid metabolism and the potential to gain
Publikováno v:
Obesity (Silver Spring)
Nonalcoholic fatty liver disease (NAFLD) is a major health problem and its prevalence has increased in recent years, concurrent with rising rates of obesity and other metabolic diseases. Currently, there are no FDA-approved pharmacological therapies
Autor:
Elizabeth J. Parks, Ayman H. Gaballah, Takhar Kasumov, Camila Manrique-Acevedo, Timothy J. Garrett, Justine M. Mucinski
Publikováno v:
Lipids. 55:387-393
This short report describes the relationships between concentrations of ceramides (CER), diacylglycerols (DAG), triacylglycerols (TAG) in very low-density lipoproteins (VLDL) particles, and hepatic lipid accumulation. VLDL particles were isolated fro
Autor:
Justine M. Mucinski, Mary P. Moore, Elizabeth J. Parks, Naren S. Nallapeta, R. Scott Rector, Jamal A. Ibdah
Publikováno v:
Diabetes. 70
Insulin resistance is a key characteristic in the development of nonalcoholic fatty liver disease (NAFLD) and NASH. The present study tested the effects of lifestyle intervention (9 months, energy restriction, high intensity interval training) on glu
Autor:
Michael E. Lassman, Elizabeth J. Parks, Stephen F. Previs, Magdalene Szuszkiewicz-Garcia, Maria A. Ramos-Roman, David G. McLaren, Jennifer E. Vena, Sudha S. Shankar, Justine M. Mucinski
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 320(4)
A novel method to test human intestinal lipid handling using stable isotope labeling is presented and, for the first time, plasma appearance and lipid turnover were quantified in 12 healthy men following meals with varying amounts of fat. The method
Autor:
Elizabeth J. Parks, Justine M. Mucinski, Mary P. Moore, R. Scott Rector, Jamal A. Ibdah, Neal Sharma
Publikováno v:
Diabetes. 69
Hepatic de novo lipogenesis (DNL) contributes to the development of nonalcoholic fatty liver disease (NAFLD) and the more advanced form, nonalcoholic steatohepatitis (NASH). The purpose of the present study was to test the effects of glucose control
Autor:
Justine M. Mucinski, Mary P. Moore
Publikováno v:
The Journal of Physiology. 598:3327-3328
Autor:
Justine M. Mucinski
Publikováno v:
Diabetes. 68
Ceramides (CER) have been implicated, along with other lipotoxic lipids (diacylglycerols, triacylglycerols, TG) that play important roles in the development and progression of nonalcoholic fatty liver disease (NAFLD). No study to date has measured CE