Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Justine D. Rose"'
Autor:
Jan Weber, Justine D Rose, Ana C Vazquez, Dane Winner, Nicolas Margot, Damian J McColl, Michael D Miller, Miguel E Quiñones-Mateu
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65631 (2013)
Most studies describing phenotypic resistance to integrase strand transfer inhibitors have analyzed viruses carrying only patient-derived HIV-1 integrase genes (INT-recombinant viruses). However, to date, many of the patients on INSTI-based treatment
Externí odkaz:
https://doaj.org/article/cdf2f9aec6404be7b22c7ae4ed2c43b3
Publikováno v:
Protein Science. 22:1646-1654
The low solubility of many proteins hinders large scale expression and purification as well as biophysical measurements. Here, we devised a general strategy to solubilize a protein by conjugating it at a solvent-exposed position to a 6 kDa protein th
Autor:
Justine D. Rose, Vicente Soriano, Ariel M. Rhea, David Robertson, John Archer, Doug Wylie, Ana C. Vazquez, Dane Winner, Eric J. Arts, Alison Wright, Miguel E. Quiñones-Mateu, Kevin King, Paul D. Olivo, Richard M. Gibson, Eva Poveda, Jan Weber, Kenneth R. Henry
Publikováno v:
Journal of Clinical Microbiology. 51:1517-1527
CCR5 antagonists are a powerful new class of antiretroviral drugs that require a companion assay to evaluate the presence of CXCR4-tropic (non-R5) viruses prior to use in human immunodeficiency virus (HIV)-infected individuals. In this study, we have
Publikováno v:
Current Opinion in HIV and AIDS. 4:136-142
Purpose of review HIV-1 entry into target cells is a complex multistage process involving the envelope glycoprotein, primary cellular receptor CD4, and at least two main cellular coreceptors, CCR5 and CXCR4. The identification of the HIV-1 coreceptor
Autor:
Vicente Soriano, Alison Wright, Paul D. Olivo, Ana C. Vazquez, Eric J. Arts, Kenneth R. Henry, Doug Wylie, Miguel E. Quiñones-Mateu, Justine D. Rose, Benigno Rodriguez, Ariel M. Rhea, Nizar Mohamed, Richard M. Gibson, Dane Winner, Kevin King, Jennifer Pappas, Jan Weber
Publikováno v:
Antimicrobial agents and chemotherapy. 55(8)
Twenty-six antiretroviral drugs (ARVs), targeting five different steps in the life cycle of the human immunodeficiency virus type 1 (HIV-1), have been approved for the treatment of HIV-1 infection. Accordingly, HIV-1 phenotypic assays based on common