Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Justine D. Miller"'
Autor:
Sally Temple, Richard J. Davis, Cuiping Zhao, Suzanne Kawola, Justine D. Miller, Nathan C. Boles, Jeffrey H. Stern
Degenerative retinal diseases such as age-related macular degeneration (AMD) are the leading cause of irreversible vision loss worldwide. AMD is characterized by the degeneration of retinal pigment epithelial (RPE) cells, which are a monolayer of cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699a7d90028d1639a502032ff9e65e35
https://europepmc.org/articles/PMC5614251/
https://europepmc.org/articles/PMC5614251/
Autor:
Anna Baccei, Tan A. Ince, Mark D. Fleming, Katelyn E. Gagne, Rebecca L. Zon, Erin M. McLoughlin, Odelya Hartung, Ellis J. Neufeld, Paul H. Lerou, George Q. Daley, Suneet Agarwal, Anne Cherry, Bryan L. Gorman, Justine D. Miller, Jin Zhang
Publikováno v:
Stem Cells. 31:1287-1297
In congenital mitochondrial DNA (mtDNA) disorders, a mixture of normal and mutated mtDNA (termed heteroplasmy) exists at varying levels in different tissues, which determines the severity and phenotypic expression of disease. Pearson marrow pancreas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c26eb15dc63fdbb116053bd403ca43b4
https://doi.org/10.1002/stem.1354
https://doi.org/10.1002/stem.1354
Autor:
M. William Lensch, Alan D. D'Andrea, Karyn M. Austin, Justine D. Miller, Thorsten M. Schlaeger, Asmin Tulpule, Akiko Shimamura, George Q. Daley
Publikováno v:
Blood. 115:3453-3462
Fanconi anemia (FA) is a genetically heterogeneous, autosomal recessive disorder characterized by pediatric bone marrow failure and congenital anomalies. The effect of FA gene deficiency on hematopoietic development in utero remains poorly described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae4d6d7dcd5be72f54a4f88886b285b
https://doi.org/10.1182/blood-2009-10-246694
https://doi.org/10.1182/blood-2009-10-246694
Autor:
In-Hyun Park, Thorsten M. Schlaeger, Christine Ladd-Acosta, Martin J. Aryee, Bo Wen, Akiko Doi, Junsung Rho, Rafael A. Irizarry, George Q. Daley, Justine D. Miller, Andrew P. Feinberg, Brian R. Herb, Sabine Loewer, Peter Murakami
Publikováno v:
Nature Genetics. 41:1350-1353
Induced pluripotent stem (iPS) cells are derived by epigenetic reprogramming, but their DNA methylation patterns have not yet been analyzed on a genome-wide scale. Here, we find substantial hypermethylation and hypomethylation of cytosine-phosphate-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ca6398082c74ec167c7a6eb612b812
https://doi.org/10.1038/ng.471
https://doi.org/10.1038/ng.471
Autor:
Kitwa Ng, Justine D. Miller, Kitai Kim, Achia Urbach, Hongguang Huo, In-Hyun Park, Yuin-Han Loh, Garrett C. Heffner, George Q. Daley, Suneet Agarwal
Publikováno v:
Blood. 113:5476-5479
Human dermal fibroblasts obtained by skin biopsy can be reprogrammed directly to pluripotency by the ectopic expression of defined transcription factors. Here, we describe the derivation of induced pluripotent stem cells from CD34+ mobilized human pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8042b816319af3d10ef5e9df808bd11c
https://doi.org/10.1182/blood-2009-02-204800
https://doi.org/10.1182/blood-2009-02-204800
Autor:
Kevin A. Wilkinson, Sara R. Wilkinson, Steven V. Hughes, Jessica Schlier, David K. Lewis, Bansi L. Kalra, Justine D. Miller
Publikováno v:
International Journal of Chemical Kinetics. 38:475-482
The Arrhenius parameters for the gas phase, unimolecular structural isomerizations of 1,1,2-trimethylcyclopropane to three isomeric methylpentenes and two dimethylbutenes have been determined over a wide range of temperatures, 688–1124 K, using bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bb1e1284a6c470b57679c166d7dbdbf
https://doi.org/10.1002/kin.20184
https://doi.org/10.1002/kin.20184
Autor:
Sally Temple, Janmeet S. Saini, Jeffrey H. Stern, Thomas R. Kiehl, Nathan C. Boles, Qingjie Wang, Timothy A. Blenkinsop, Barbara Corneo, Justine D. Miller
Publikováno v:
Cell Stem Cell. 20:635-647.e7
Age-related macular degeneration (AMD) affects the retinal pigment epithelium (RPE), a cell monolayer essential for photoreceptor survival, and is the leading cause of vision loss in the elderly. There are no disease-altering therapies for dry AMD, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e629e7bc4e61ec19304e037470d867
https://doi.org/10.1016/j.stem.2016.12.015
https://doi.org/10.1016/j.stem.2016.12.015
Autor:
Lorenz Studer, Justine D. Miller
Publikováno v:
Aging (Albany NY)
Human induced pluripotent stem cell (iPSC) technology [1] holds the promise of recreating disease in vitro in a patient-specific manner. There has been considerable success in using iPSC models to study early-onset genetic diseases, such as our own w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216bebcecfd01bf103b28eda4b5ab62e
https://pubmed.ncbi.nlm.nih.gov/24799443
https://pubmed.ncbi.nlm.nih.gov/24799443
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 767
This chapter describes a protocol for deriving induced pluripotent stem cells (iPSCs) from human fibroblasts. Human fibroblasts, cultured in fibroblast medium, are infected with a cocktail of retroviral vectors expressing the transcription factors OC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::384cfa7ae5d980f513386dc803d5e601
https://pubmed.ncbi.nlm.nih.gov/21822867
https://pubmed.ncbi.nlm.nih.gov/21822867
Publikováno v:
Methods in Molecular Biology ISBN: 9781617792007
This chapter describes a protocol for deriving induced pluripotent stem cells (iPSCs) from human fibroblasts. Human fibroblasts, cultured in fibroblast medium, are infected with a cocktail of retroviral vectors expressing the transcription factors OC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baca0feaec1af4b7e64781611a30a07b
https://doi.org/10.1007/978-1-61779-201-4_5
https://doi.org/10.1007/978-1-61779-201-4_5