Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Justine Bellier"'
Autor:
Gaurav Dube, Assia Tiamiou, Martin Bizet, Yasmine Boumahd, Imène Gasmi, Rebekah Crake, Justine Bellier, Marie-Julie Nokin, Emilie Calonne, Rachel Deplus, Tom Wissocq, Olivier Peulen, Vincent Castronovo, François Fuks, Akeila Bellahcène
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Aerobic glycolysis, also known as the Warburg effect, is predominantly upregulated in a variety of solid tumors, including breast cancer. We have previously reported that methylglyoxal (MG), a very reactive by-product of glycolysi
Externí odkaz:
https://doaj.org/article/99203b58e323473ab885bd1de0fe091d
Autor:
Gilles Rademaker, Brunella Costanza, Justine Bellier, Michael Herfs, Raphaël Peiffer, Ferman Agirman, Naïma Maloujahmoum, Yvette Habraken, Philippe Delvenne, Akeila Bellahcène, Vincent Castronovo, Olivier Peulen
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/3c391d5f130d4134b472946773f3313a
Autor:
Marie-Julie Nokin, Justine Bellier, Florence Durieux, Olivier Peulen, Gilles Rademaker, Maude Gabriel, Christine Monseur, Benoit Charloteaux, Lieven Verbeke, Steven van Laere, Patrick Roncarati, Michael Herfs, Charles Lambert, Jean Scheijen, Casper Schalkwijk, Alain Colige, Jo Caers, Philippe Delvenne, Andrei Turtoi, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-19 (2019)
Abstract Background Elevated aerobic glycolysis rate is a biochemical alteration associated with malignant transformation and cancer progression. This metabolic shift unavoidably generates methylglyoxal (MG), a potent inducer of dicarbonyl stress thr
Externí odkaz:
https://doaj.org/article/65d51f1a7dd24b1081a694086ad67b98
Autor:
Justine Bellier, Marie-Julie Nokin, Maurine Caprasse, Assia Tiamiou, Arnaud Blomme, Jean L. Scheijen, Benjamin Koopmansch, Gillian M. MacKay, Barbara Chiavarina, Brunella Costanza, Gilles Rademaker, Florence Durieux, Ferman Agirman, Naïma Maloujahmoum, Pino G. Cusumano, Pierre Lovinfosse, Hing Y. Leung, Frédéric Lambert, Vincent Bours, Casper G. Schalkwijk, Roland Hustinx, Olivier Peulen, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1400-1416.e6 (2020)
Summary: The use of cetuximab anti-epidermal growth factor receptor (anti-EGFR) antibodies has opened the era of targeted and personalized therapy in colorectal cancer (CRC). Poor response rates have been unequivocally shown in mutant KRAS and are ev
Externí odkaz:
https://doaj.org/article/96932a30ac1e4a57b60f7bff8ef7fecf
Autor:
Eva Lardé, Philippe Karoyan, Olivier Peulen, Justine Bellier, Marie-Julie Nokin, Vincenzo Castronovo, Akeila Bellahcene
Publikováno v:
Diabetes Research and Clinical Practice. 148:200-211
Diabetes is one of the most frequent diseases throughout the world and its incidence is predicted to exponentially progress in the future. This metabolic disorder is associated with major complications such as neuropathy, retinopathy, atherosclerosis
Autor:
Yasmine Boumahd, Akeila Bellahcene, Martin Bizet, Rachel Deplus, Vincent Castronovo, Marie-Julie Nokin, Gaurav Dube, Olivier Peulen, Emilie Calonne, Justine Bellier, François Fuks
Publikováno v:
IBJ Plus.
Autor:
David Spiegel, Koji Uchida, Craig A. Hutton, Justine Bellier, Akeila Bellahcene, Florence Durieux, Olivier Peulen, Marie-Julie Nokin, Vincenzo Castronovo, James R. Cochrane
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports
Metabolic reprogramming toward aerobic glycolysis unavoidably favours methylglyoxal (MG) and advanced glycation end products (AGEs) formation in cancer cells. MG was initially considered a highly cytotoxic molecule with potential anti-cancer value. H
Autor:
Justine Bellier, Marie-Julie Nokin, Maurine Caprasse, Assia Tiamiou, Arnaud Blomme, Jean L. Scheijen, Benjamin Koopmansch, Gillian M. MacKay, Barbara Chiavarina, Brunella Costanza, Gilles Rademaker, Florence Durieux, Ferman Agirman, Naïma Maloujahmoum, Pino G. Cusumano, Pierre Lovinfosse, Hing Y. Leung, Frédéric Lambert, Vincent Bours, Casper G. Schalkwijk, Roland Hustinx, Olivier Peulen, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
Cell Reports, 30(5), 1400-1416.e6. Cell Press
Cell Reports, Vol 30, Iss 5, Pp 1400-1416.e6 (2020)
Cell Reports, Vol 30, Iss 5, Pp 1400-1416.e6 (2020)
Summary: The use of cetuximab anti-epidermal growth factor receptor (anti-EGFR) antibodies has opened the era of targeted and personalized therapy in colorectal cancer (CRC). Poor response rates have been unequivocally shown in mutant KRAS and are ev
Autor:
Justine Leenders, Assia Tiamiou, Andrei Turtoi, Pascal de Tullio, Arnaud Blomme, Vincenzo Castronovo, Gilles Rademaker, Justine Bellier, Brunella Costanza, Olivier Peulen, Akeila Bellahcene, Philippe Delvenne, Elettra Bianchi
Publikováno v:
International Journal of Cancer
International Journal of Cancer, Wiley, 2019, 145 (6), pp.1570-1584. ⟨10.1002/ijc.32247⟩
International Journal of Cancer, Wiley, 2019, 145 (6), pp.1570-1584. ⟨10.1002/ijc.32247⟩
International audience; Pancreatic ductal adenocarcinoma (PDAC) remains a deadly malignancy with no efficient therapy available up-to-date. Glycolysis is the main provider of energetic substrates to sustain cancer dissemination of PDAC. Accordingly,
Autor:
Gilles, Rademaker, Vincent, Hennequière, Laura, Brohée, Marie-Julie, Nokin, Pierre, Lovinfosse, Florence, Durieux, Stéphanie, Gofflot, Justine, Bellier, Brunella, Costanza, Michael, Herfs, Raphael, Peiffer, Lucien, Bettendorff, Christophe, Deroanne, Marc, Thiry, Philippe, Delvenne, Roland, Hustinx, Akeila, Bellahcène, Vincent, Castronovo, Olivier, Peulen
Publikováno v:
Oncogene
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related death. Therapeutic options remain very limited and are based on classical chemotherapies. Energy metabolism reprogramming appears as an emerging hallmark of cancer a