Subclinical dose irradiation triggers human breast cancer migration via mitochondrial reactive oxygen species

Autor: Justin D. Rondeau, Justine A. Van de Velde, Yasmine Bouidida, Pierre Sonveaux

Publikováno v: Cancer & Metabolism, Vol 12, Iss 1, Pp 1-11 (2024)

Abstract Background Despite technological advances in radiotherapy, cancer cells at the tumor margin and in diffusive infiltrates can receive subcytotoxic doses of photons. Even if only a minority of cancer cells are concerned, phenotypic consequence

Externí odkaz: https://doaj.org/article/528775e6f8074008a97e3952988e19ef

Mitochondrial Protein Cox7b Is a Metabolic Sensor Driving Brain-Specific Metastasis of Human Breast Cancer Cells

Autor: Marine C. N. M. Blackman, Tania Capeloa, Justin D. Rondeau, Luca X. Zampieri, Zohra Benyahia, Justine A. Van de Velde, Maude Fransolet, Evangelos P. Daskalopoulos, Carine Michiels, Christophe Beauloye, Pierre Sonveaux

Publikováno v: Cancers; Volume 14; Issue 18; Pages: 4371
Cancers, Vol. 14, no.18, p. 4371 (2022)
Blackman, M C N M, Capeloa, T, Rondeau, J D, Zampieri, L X, Benyahia, Z, Van de Velde, J A, Fransolet, M, Daskalopoulos, E P, Michiels, C, Beauloye, C & Sonveaux, P 2022, ' Mitochondrial Protein Cox7b Is a Metabolic Sensor Driving Brain-Specific Metastasis of Human Breast Cancer Cells ', Cancers, vol. 14, no. 18, 4371 . https://doi.org/10.3390/cancers14184371

Distant metastases are detrimental for cancer patients, but the increasingly early detection of tumors offers a chance for metastasis prevention. Importantly, cancers do not metastasize randomly: depending on the type of cancer, metastatic progenitor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d00440a861394b3d0eb340b28e7b3f
https://doi.org/10.3390/cancers14184371