Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Justina Ucheojor Onwuka"'
Autor:
Marc Chadeau-Hyam, Paolo Vineis, Caroline Relton, Mattias Johansson, Gianluca Severi, Roger L Milne, Melissa C Southey, Pierre-Antoine Dugué, Florence Guida, Mikael Johansson, Torkjel Sandanger, Justina Ucheojor Onwuka, Ryan Langdon, Therese Haugdahl Nøst, Hilary A. Robbins, Matthew Suderman
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective Screening high-risk individuals with low-dose CT reduces mortality from lung cancer, but many lung cancers occur in individuals who are not eligible for screening. Risk biomarkers may be useful to refine risk models and improve screening el
Externí odkaz:
https://doaj.org/article/31adadfff44f48119b68988cdec01203
Autor:
Justina Ucheojor Onwuka, Dapeng Li, Yupeng Liu, Hao Huang, Jing Xu, Ying Liu, Yuanyuan Zhang, Yashuang Zhao
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Differential DNA methylation panel derived from peripheral blood could serve as biomarkers of CRC susceptibility. However, most of the previous studies utilized post-diagnostic blood DNA which may be markers of disease rather than
Externí odkaz:
https://doaj.org/article/ede6b1a1ea8e423cbaa2009082673a95
Autor:
Justina Ucheojor Onwuka, Akinkunmi Paul Okekunle, Olaniyi Matthew Olutola, Onoja Matthew Akpa, Rennan Feng
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Existing data from several reports on the association between lipid profile and ovarian tumour (OT) suggests divergent conclusions. Our aim was to examine whether circulating lipid profile: total cholesterol (TC), triglyceride (TG
Externí odkaz:
https://doaj.org/article/172813795ec945b3b86801eff2e0d93a
Autor:
Hao Huang, Jinming Fu, Lei Zhang, Jing Xu, Dapeng Li, Justina Ucheojor Onwuka, Ding Zhang, Liyuan Zhao, Simin Sun, Lin Zhu, Ting Zheng, Chenyang Jia, Binbin Cui, Yashuang Zhao
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundAberrant DNA methylation is a critical regulator of gene expression and plays a crucial role in the occurrence, progression, and prognosis of colorectal cancer (CRC). We aimed to identify methylation-driven genes by integrative epigenetic a
Externí odkaz:
https://doaj.org/article/49d1e4df83414642b06c21ce024afb2d
Autor:
Tingting Xia, Hongru Sun, Hao Huang, Haoran Bi, Rui Pu, Lei Zhang, Yuanyuan Zhang, Ying Liu, Jing Xu, Justina Ucheojor Onwuka, Yupeng Liu, Binbin Cui, Yashuang Zhao
Publikováno v:
Endocrine Connections, Vol 8, Iss 7, Pp 979-987 (2019)
According to its incidence patterns, colorectal cancer (CRC) tends to occur more frequently in males than in females, and the evidence shows that CRC is a hormone-related tumor. These findings indicate that androgen receptor (AR) gene methylation mig
Externí odkaz:
https://doaj.org/article/e7a3859346234e03bdb60ad2cdf1a29f
Autor:
Jinming Fu, Yupeng Liu, Lei Zhang, Lu Zhou, Dapeng Li, Hude Quan, Lin Zhu, Fulan Hu, Xia Li, Shuhan Meng, Ran Yan, Suhua Zhao, Justina Ucheojor Onwuka, Baofeng Yang, Dianjun Sun, Yashuang Zhao
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 19 (2020)
Background Nonpharmacologic interventions that modify lifestyle can lower blood pressure (BP) and have been assessed in numerous randomized controlled trials and pairwise meta‐analyses. It is still unclear which intervention would be most efficacio
Externí odkaz:
https://doaj.org/article/7639a131535f4bc88ffeb826d20d83df
Autor:
Yan Zhao, Xiaoning Ji, Panpan Guo, Justina Ucheojor Onwuka, Ying Zhang, Hui He, Chao Luo, Liang Wang, Ningxin Tang, Jueqiong Zhao, Rennan Feng
Publikováno v:
International Journal of Food Sciences and Nutrition. 73:552-563
The purpose of this study was to explore the possible association between dairy and NCDs and identify possible dairy types that could lower the odds of NCDs. Data were from the 2003–2016 NHANES, a cross-sectional study with 20,297 adults. Multivari
Autor:
Therese Martin Cheteu Wabo, Changhao Sun, Justina Ucheojor Onwuka, Jackson Sira, Tianshu Han, Victorine Raïssa Ngo Nkondjock
Publikováno v:
Aging (Albany NY)
Diet quality fluctuates throughout one's adulthood, yet it remains unclear how long-term diet quality changes are related to type 2 diabetes mellitus (T2DM) and its biomarkers. We aimed to examine the association of long-term diet quality with T2DM a
Autor:
Yashuang Zhao, Hao Huang, Justina Ucheojor Onwuka, Yuanyuan Zhang, Lei Zhang, Binbin Cui, Simin Sun, Jinming Fu, Ying Liu, Ding Zhang, Liyuan Zhao, Jing Xu, Hongru Sun
Publikováno v:
Aging. 12:20561-20586
Homogenous DNA methylation clearly affects clinical outcomes. However, less is known about the effects of heterogeneous methylation. We aimed to investigate the different effects between CASK promoter methylation heterogeneity and homogeneity on colo
Autor:
Yupeng Liu, ZhiGang Zhao, HongYu Xu, Jing Xu, Wenjing Tian, Hongru Sun, Justina Ucheojor Onwuka, Lei Zhang, Dapeng Li, Yashuang Zhao
Publikováno v:
Aging (Albany NY)
The early diagnosis and accurate prognosis prediction of esophageal cancer is an essential part of improving survival. However, these diseases lack effective and specific markers. A total of 1,744 samples of HumanMethylation450 data were integrated t