Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Justina Almodovar"'
Autor:
Anna Rodina, Chao Xu, Chander S. Digwal, Suhasini Joshi, Yogita Patel, Anand R. Santhaseela, Sadik Bay, Swathi Merugu, Aftab Alam, Pengrong Yan, Chenghua Yang, Tanaya Roychowdhury, Palak Panchal, Liza Shrestha, Yanlong Kang, Sahil Sharma, Justina Almodovar, Adriana Corben, Mary L. Alpaugh, Shanu Modi, Monica L. Guzman, Teng Fei, Tony Taldone, Stephen D. Ginsberg, Hediye Erdjument-Bromage, Thomas A. Neubert, Katia Manova-Todorova, Meng-Fu Bryan Tsou, Jason C. Young, Tai Wang, Gabriela Chiosis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-26 (2023)
Abstract Systems-level assessments of protein-protein interaction (PPI) network dysfunctions are currently out-of-reach because approaches enabling proteome-wide identification, analysis, and modulation of context-specific PPI changes in native (unen
Externí odkaz:
https://doaj.org/article/bd99358101954a8492861b762bbf8146
Autor:
Suhasini Joshi, Erica DaGama Gomes, Tai Wang, Adriana Corben, Tony Taldone, Srinivasa Gandu, Chao Xu, Sahil Sharma, Salma Buddaseth, Pengrong Yan, Lon Yin L. Chan, Askan Gokce, Vinagolu K. Rajasekhar, Lisa Shrestha, Palak Panchal, Justina Almodovar, Chander S. Digwal, Anna Rodina, Swathi Merugu, NagaVaraKishore Pillarsetty, Vlad Miclea, Radu I. Peter, Wanyan Wang, Stephen D. Ginsberg, Laura Tang, Marissa Mattar, Elisa de Stanchina, Kenneth H. Yu, Maeve Lowery, Olivera Grbovic-Huezo, Eileen M. O’Reilly, Yelena Janjigian, John H. Healey, William R. Jarnagin, Peter J. Allen, Chris Sander, Hediye Erdjument-Bromage, Thomas A. Neubert, Steven D. Leach, Gabriela Chiosis
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-20 (2021)
Joshi, Gomes et al. employ a chemical modulation approach of the cellular interactome to a hyperconnectivity state and show association with the increased response of pancreatic cancer cell lines to specific drugs, including those that target the MAP
Externí odkaz:
https://doaj.org/article/c73d69998238486ba39d6f85c901b64d
Autor:
Alexander Bolaender, Danuta Zatorska, Huazhong He, Suhasini Joshi, Sahil Sharma, Chander S. Digwal, Hardik J. Patel, Weilin Sun, Brandon S. Imber, Stefan O. Ochiana, Maulik R. Patel, Liza Shrestha, Smit. K. Shah, Shuo Wang, Rashad Karimov, Hui Tao, Pallav D. Patel, Ananda Rodilla Martin, Pengrong Yan, Palak Panchal, Justina Almodovar, Adriana Corben, Andreas Rimner, Stephen D. Ginsberg, Serge Lyashchenko, Eva Burnazi, Anson Ku, Teja Kalidindi, Sang Gyu Lee, Milan Grkovski, Bradley J. Beattie, Pat Zanzonico, Jason S. Lewis, Steve Larson, Anna Rodina, Nagavarakishore Pillarsetty, Viviane Tabar, Mark P. Dunphy, Tony Taldone, Fumiko Shimizu, Gabriela Chiosis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Here, the authors show structural, biochemical, and functional insights into the discovery of epichaperome‐ directed chemical probes for use in central nervous system diseases. Probes emerging from this work have translated to human clinical studie
Externí odkaz:
https://doaj.org/article/ed3d8f0c921541cb8291f5f96c64889e
Autor:
Chander Singh Digwal, Peter J. Allen, Thomas A. Neubert, Swathi Merugu, Eileen M. O'Reilly, Wanyan Wang, Lon Yin L. Chan, Vinagolu K. Rajasekhar, Suhasini Joshi, Tony Taldone, Nagavarakishore Pillarsetty, Olivera Grbovic-Huezo, Erica DaGama Gomes, Maeve A. Lowery, Srinivasa Gandu, Anna Rodina, Stephen D. Ginsberg, Gabriela Chiosis, Vlad Miclea, Elisa de Stanchina, Laura H. Tang, Palak Panchal, Chris Sander, Lisa Shrestha, Kenneth H. Yu, Chao Xu, Steven D. Leach, Hediye Erdjument-Bromage, Marissa Mattar, Pengrong Yan, Radu I Peter, John H. Healey, Adriana D. Corben, Justina Almodovar, Sahil Sharma, William R. Jarnagin, Yelena Y. Janjigian, Salma Buddaseth, Tai Wang, Askan Gokce
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-20 (2021)
Communications Biology
Communications Biology
Cancer cell plasticity due to the dynamic architecture of interactome networks provides a vexing outlet for therapy evasion. Here, through chemical biology approaches for systems level exploration of protein connectivity changes applied to pancreatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07f97d15df068541c2e0f0dca203cd0
https://doaj.org/article/c73d69998238486ba39d6f85c901b64d
https://doaj.org/article/c73d69998238486ba39d6f85c901b64d
Autor:
Mark Dunphy, Brandon S Imber, Sang-gyu Lee, Teja Kalidindi, Justina Almodovar, Eva Burnazi, Bradley J. Beattie, Fumiko Shimizu, Anson Ku, Andreas Rimner, Pallav D. Patel, Adriana D. Corben, Milan Grkovski, Tony Taldone, Pat Zanzonico, Sahil Sharma, Rashad R. Karimov, Viviane Tabar, Anna Rodina, Stephen D. Ginsberg, Liza Shrestha, Danuta Zatorska, Jason S. Lewis, Suhasini Joshi, Weilin Sun, Nagavarakishore Pillarsetty, Palak Panchal, Serge K. Lyashchenko, Chander Singh Digwal, Stefan O. Ochiana, Ananda Rodilla Martin, Gabriela Chiosis, Pengrong Yan, Alexander Bolaender, Hardik J. Patel, Huazhong He, Steve Larson, Shuo Wang, Maulik R. Patel, Hui Tao, Smit K. Shah
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Diseases are a manifestation of how thousands of proteins interact. In several diseases, such as cancer and Alzheimer’s disease, proteome-wide disturbances in protein-protein interactions are caused by alterations to chaperome scaffolds termed epic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669c4abb67740cffe82ffa7bf75d52ff
https://pubmed.ncbi.nlm.nih.gov/34344873
https://pubmed.ncbi.nlm.nih.gov/34344873