Zobrazeno 1 - 10 of 78 pro vyhledávání: '"Justin Y Newberg"'
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Akademický článek
Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression.
Autor: Aziz Aiderus, Justin Y Newberg, Liliana Guzman-Rojas, Ana M Contreras-Sandoval, Amanda L Meshey, Devin J Jones, Felipe Amaya-Manzanares, Roberto Rangel, Jerrold M Ward, Song-Choon Lee, Kenneth Hon-Kim Ban, Keith Rogers, Susan M Rogers, Luxmanan Selvanesan, Leslie A McNoe, Neal G Copeland, Nancy A Jenkins, Kenneth Y Tsai, Michael A Black, Karen M Mann, Michael B Mann
Publikováno v: PLoS Genetics, Vol 17, Iss 8, p e1009094 (2021)
The systematic identification of genetic events driving cellular transformation and tumor progression in the absence of a highly recurrent oncogenic driver mutation is a challenge in cutaneous oncology. In cutaneous squamous cell carcinoma (cuSCC), t
Externí odkaz: https://doaj.org/article/9ca296e0d3ca42438be6049b510b1dcf
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2
Akademický článek
RBFOX2 deregulation promotes pancreatic cancer progression and metastasis through alternative splicing
Autor: Michelle Maurin, Mohammadreza Ranjouri, Cristina Megino-Luque, Justin Y. Newberg, Dongliang Du, Katelyn Martin, Robert E. Miner, Mollie S. Prater, Dave Keng Boon Wee, Barbara Centeno, Shondra M. Pruett-Miller, Paul Stewart, Jason B. Fleming, Xiaoqing Yu, Jose Javier Bravo-Cordero, Ernesto Guccione, Michael A. Black, Karen M. Mann
Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract RNA splicing is an important biological process associated with cancer initiation and progression. However, the contribution of alternative splicing to pancreatic cancer (PDAC) development is not well understood. Here, we identify an enrichm
Externí odkaz: https://doaj.org/article/0792cf6371164a1eae6f885ff6f53bed
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3
Akademický článek
Automated analysis and reannotation of subcellular locations in confocal images from the Human Protein Atlas.
Autor: Jieyue Li, Justin Y Newberg, Mathias Uhlén, Emma Lundberg, Robert F Murphy
Publikováno v: PLoS ONE, Vol 7, Iss 11, p e50514 (2012)
The Human Protein Atlas contains immunofluorescence images showing subcellular locations for thousands of proteins. These are currently annotated by visual inspection. In this paper, we describe automated approaches to analyze the images and their us
Externí odkaz: https://doaj.org/article/d8927dd0e7a442fba3ca712883cd90ce
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4
Akademický článek
Source, co-occurrence, and prognostic value of PTEN mutations or loss in colorectal cancer
Autor: Ilya G. Serebriiskii, Valerii A. Pavlov, Grigorii V. Andrianov, Samuel Litwin, Stanley Basickes, Justin Y. Newberg, Garrett M. Frampton, Joshua E. Meyer, Erica A. Golemis
Publikováno v: npj Genomic Medicine, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Somatic PTEN mutations are common and have driver function in some cancer types. However, in colorectal cancers (CRCs), somatic PTEN-inactivating mutations occur at a low frequency (~8–9%), and whether these mutations are actively selected
Externí odkaz: https://doaj.org/article/05b5d8139d0048c0b81f41974e799bcd
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9
Figure S1, Figure S2, Figure S3, Figure S4, Figure S5 from Identification of New Tumor Suppressor Genes in Triple-Negative Breast Cancer
Autor: Nancy A. Jenkins, Neal G. Copeland, Justin Y. Newberg, Michiko Kodama, Takahiro Kodama, Liliana Guzman-Rojas, Roberto Rangel
Figure S1. Expression of ZNF326 a in human breast cancer tissues. The images show a representative scoring intensities following immunostaining with anti-ZNF326 antibody (Range of low, moderate and high). Figure S2. RT-PCR analysis of the candidate c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a28bfb0ff426045629be2ea7c8d5510
https://doi.org/10.1158/0008-5472.22414506
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