Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Justin Wray"'
Autor:
Justin Wray, Elizabeth A Williamson, Melanie Royce, Montaser Shaheen, Brian D Beck, Suk-Hee Lee, Jac A Nickoloff, Robert Hromas
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5323 (2009)
DNA replication produces tangled, or catenated, chromatids, that must be decatenated prior to mitosis or catastrophic genomic damage will occur. Topoisomerase IIalpha (Topo IIalpha) is the primary decatenating enzyme. Cells monitor catenation status
Externí odkaz:
https://doaj.org/article/aec086a5d6614509bb6f1175222a5e04
Supplementary Figures 1-3 from Distinct RAD51 Associations with RAD52 and BCCIP in Response to DNA Damage and Replication Stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f4702d4a2c7c2f74ced12b0d77683d
https://doi.org/10.1158/0008-5472.22373666.v1
https://doi.org/10.1158/0008-5472.22373666.v1
Autor:
Thomas J. George, Anamaria R. Yeung, Karen Daily, Roi Dagan, Rana Fawzi Hawamdeh, Nalini Hasija, Robert A. Zlotecki, Judith L. Lightsey, Long H. Dang, Justin Wray, Jose G. Trevino, Paul Okunieff
Publikováno v:
Oncology Letters
Chemotherapy and targeted therapies are effective palliative options for numerous unresectable or metastatic cancers. However, treatment resistance inevitably develops leading to mortality. In a subset of patients, systemic therapy appears to control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ddc598a1e0385eef305598cec2ab0f2
http://europepmc.org/articles/PMC5403710
http://europepmc.org/articles/PMC5403710
Autor:
Justin Wray, Daniel J. Indelicato, Stella Flampouri, Zuofeng Li, Nancy P. Mendenhall, Bradford S. Hoppe, William B. Slayton, Christopher G. Morris, Michael Joyce, Eric Sandler
Publikováno v:
Pediatric Blood & Cancer. 63:1522-1526
Background Compared to X-ray radiation therapy, proton therapy (PT) reduces the radiation dose to organs at risk, which is expected to translate into fewer second cancers and less cardiac morbidity decades after treatment. The Children's Oncology Gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cc093e4855ce281f1faa704c37c45a4
https://doi.org/10.1002/pbc.26044
https://doi.org/10.1002/pbc.26044
Autor:
Kaitlin Christopherson, William M. Mendenhall, Justin Wray, Brian J. Boyce, Robert J. Amdur, Peter T. Dziegielewski, Christopher G. Morris
Publikováno v:
American journal of clinical oncology. 41(12)
Objective Patients with mucosal squamous cell carcinoma (SCC) of the head and neck almost always have a primary site in the base of tongue or tonsillar fossa. Lingual tonsillectomy has recently been advocated as part of the diagnostic evaluation as o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898f52dd294e6665efe7e69cc16e3df2
https://pubmed.ncbi.nlm.nih.gov/29746367
https://pubmed.ncbi.nlm.nih.gov/29746367
Autor:
Roland-Austin Federico, Ravneet Bajwa, William Paul Skelton, Jameel Muzaffar, Long H. Dang, Robert A. Zlotecki, Azka Ali, Justin Wray, Thu-Cuc Nguyen, Rohit Bishnoi, Shahla Bari
Publikováno v:
Oxford Medical Case Reports
Castration-resistant prostate cancer is an incurable disease. To date, six agents-abiraterone, enzalutamide, docetaxel, cabazitaxel, radium-223 and sipuleucel-T- have shown clinical efficacy in phase III clinical trials, leading to their FDA approval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce48af713784c8755472bfc3c7ede11
https://doi.org/10.1093/omcr/omx078
https://doi.org/10.1093/omcr/omx078
Autor:
Elizabeth A. Williamson, Suk Hee Lee, Michael Byrne, Justin Wray, Jac A. Nickoloff, Robert Hromas, Brian L. Reinert, Yuehan Wu
Publikováno v:
Annals of the New York Academy of Sciences. 1310:89-97
Chromosome translocations are caused by inappropriate religation of two DNA double-strand breaks (DSBs) in heterologous chromosomes. These DSBs can be generated by endogenous or exogenous sources. Endogenous sources of DSBs leading to translocations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c3e9e7e887afacdea2f2787054e0820
https://doi.org/10.1111/nyas.12370
https://doi.org/10.1111/nyas.12370
Autor:
Sudha B. Singh, Rupak Pathak, Daohong Zhou, Lijian Shao, Yuehan Wu, David M. Weinstock, Elizabeth A. Williamson, Jac A. Nickoloff, Martin Hauer-Jensen, Suk Hee Lee, Virginia M. Klimek, Christopher R. Cogle, Yu Zhang, Robert Hromas, Justin Wray
Publikováno v:
Blood. 121:4359-4365
Chromosomal translocations are common contributors to malignancy, yet little is known about the precise molecular mechanisms by which they are generated. Sequencing translocation junctions in acute leukemias revealed that the translocations were like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0aae52922d50b207082324a3620b2a5
https://doi.org/10.1182/blood-2012-10-460527
https://doi.org/10.1182/blood-2012-10-460527
Autor:
Judith L. Lightsey, Justin Wray
Publikováno v:
Oxidative Stress and Antioxidant Protection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b238e49d936828e6e3ee4d250dbf9720
https://doi.org/10.1002/9781118832431.ch23
https://doi.org/10.1002/9781118832431.ch23
Autor:
Carly Murphy, A. Thomas Look, Karen W. Ho, Yebin Ahn, James F. Amatruda, Laura E. MacConaill, Charles Lee, Donna Neuberg, Keith McKenna, Neil J. Ganem, Alejandro Gutierrez, Adam Amsterdam, Eric A. Ross, Mark D. Fleming, Ilene Galinsky, Stefan Heinrichs, John P. Kanki, James R. Downing, Lisa A. Moreau, Richard Stone, Adam Johnston, Takaomi Sanda, Justin Wray, David Pellman, Jennifer Rhodes, Robert Hromas, Ina Radtke, Jeffery L. Kutok
Publikováno v:
Molecular and Cellular Biology. 29:5911-5922
A growing body of evidence indicates that early mitotic inhibitor 1 (Emi1) is essential for genomic stability, but how this function relates to embryonic development and cancer pathogenesis remains unclear. We have identified a zebrafish mutant line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618120a8d39aee2b3f38258d6c9b6d7d
https://doi.org/10.1128/mcb.00558-09
https://doi.org/10.1128/mcb.00558-09