Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Justin W. Mabin"'
1
Molecular anatomy of eosinophil activation by IL5 and IL33
Autor: Joshua M. Mitchell, Justin W. Mabin, Laura K. Muehlbauer, Douglas S. Annis, Sameer K. Mathur, Mats W. Johansson, Alex S. Hebert, Frances J. Fogerty, Joshua J. Coon, Deane F. Mosher
IL5 and IL33 are major activating cytokines that cause circulating eosinophils to polarize, adhere, and release their granule contents. We correlated microscopic features of purified human blood eosinophils stimulated for 10 min with IL5 or IL33 with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b26f3f5c6e09636afba41f549701f691
https://doi.org/10.1101/2022.12.21.521419
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2
Human spliceosomal snRNA sequence variants generate variant spliceosomes
Autor: David A. Brow, Justin W Mabin, Heidi Dvinge, Peter W. Lewis
Publikováno v: RNA. 27:1186-1203
Human pre-mRNA splicing is primarily catalyzed by the major spliceosome, comprising five small nuclear ribonucleoprotein complexes, U1, U2, U4, U5, and U6 snRNPs, each of which contains the corresponding U-rich snRNA. These snRNAs are encoded by larg
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27560177e5aa5b4daaf0f8e0fd03d88
https://doi.org/10.1261/rna.078768.121
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3
Chemical crosslinking enhances RNA immunoprecipitation for efficient identification of binding sites of proteins that photo-crosslink poorly with RNA
Autor: Ralf Bundschuh, Robert D. Patton, Lauren A. Woodward, Manu Sanjeev, Justin W. Mabin, Guramrit Singh
Publikováno v: RNA
In eukaryotic cells, proteins that associate with RNA regulate its activity to control cellular function. To fully illuminate the basis of RNA function, it is essential to identify such RNA-associated proteins, their mode of action on RNA, and their
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85cbd565ca5e91e2afee2dfa42e014c8
https://doi.org/10.1261/rna.074856.120
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4
The exon junction complex undergoes a compositional switch that alters mRNP structure and nonsense-mediated mRNA decay activity
Autor: Vicki H. Wysocki, Mengxuan Jia, Ralf Bundschuh, Guramrit Singh, Zhongxia Yi, Justin W. Mabin, Robert D. Patton, Lauren A. Woodward
SUMMARYThe exon junction complex (EJC) deposited upstream of mRNA exon junctions shapes structure, composition and fate of spliced mRNA ribonucleoprotein particles (mRNPs). To achieve this, the EJC core nucleates assembly of a dynamic shell of periph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d99a1bed7ce022d048d575c9298f462
https://doi.org/10.1101/355495
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5
Comparison of intrinsic dynamics of cytochrome p450 proteins using normal mode analysis
Autor: Shane W. Hodgson, Mariah E. Dorner, Beatrice R. Soderholm, Christopher A. Monte, Jessica M. Dulli, Justin W. Mabin, Daniel L. Mazula, Shawn W. Keenan, Sanchita Hati, Augustus Olthafer, Cody R. Fisher, Alexander M. Strom, Ryan D. McMunn, Samuel C. Fehling, Ashley E. Sexton, Brecken E. Calhoon, Michelle R. Conlon, Alyssa N. Kruger, Thomas G. Bartholow
Publikováno v: Protein Science. 24:1495-1507
Cytochrome P450 enzymes are hemeproteins that catalyze the monooxygenation of a wide-range of structurally diverse substrates of endogenous and exogenous origin. These heme monooxygenases receive electrons from NADH/NADPH via electron transfer protei
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aad466d653645f8fe73e2e3f25dbbc12
https://doi.org/10.1002/pro.2737
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6
Cloning and Identification of Recombinant Argonaute-Bound Small RNAs Using Next-Generation Sequencing
Autor: Pooja, Gangras, Daniel M, Dayeh, Justin W, Mabin, Kotaro, Nakanishi, Guramrit, Singh
Publikováno v: Methods in molecular biology (Clifton, N.J.). 1680
Argonaute proteins (AGOs) are loaded with small RNAs as guides to recognize target mRNAs. Since the target specificity heavily depends on the base complementarity between two strands, it is important to identify small guide and long target RNAs bound
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::72af8de6a15bb5ef40f621ceafbb4388
https://pubmed.ncbi.nlm.nih.gov/29030838
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7
Cloning and Identification of Recombinant Argonaute-Bound Small RNAs Using Next-Generation Sequencing
Autor: Daniel M. Dayeh, Kotaro Nakanishi, Pooja Gangras, Guramrit Singh, Justin W. Mabin
Publikováno v: Methods in Molecular Biology ISBN: 9781493973385
Argonaute proteins (AGOs) are loaded with small RNAs as guides to recognize target mRNAs. Since the target specificity heavily depends on the base complementarity between two strands, it is important to identify small guide and long target RNAs bound
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8035be80cbb64daa5b2f4a88e2558045
https://doi.org/10.1007/978-1-4939-7339-2_1
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9
The exon junction complex: a lifelong guardian of mRNA fate
Autor: Guramrit Singh, Justin W. Mabin, Lauren A. Woodward, Pooja Gangras
Publikováno v: Wiley interdisciplinary reviews. RNA. 8(3)
During messenger RNA (mRNA) biogenesis and processing in the nucleus, many proteins are imprinted on mRNAs assembling them into messenger ribonucleoproteins (mRNPs). Some of these proteins remain stably bound within mRNPs and have a long-lasting impa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7037e2689d10e1f73c313a93053fbd1
https://pubmed.ncbi.nlm.nih.gov/28008720
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