Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Justin W. Hines"'
Autor:
Kiran Kumar Solingapuram Sai, Nagaraju Bashetti, Xiaofei Chen, Skylar Norman, Justin W. Hines, Omsai Meka, J. V. Shanmukha Kumar, Sriram Devanathan, Gagan Deep, Cristina M. Furdui, Akiva Mintz
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Background Reactive oxygen species (ROS)-induced oxidative stress damages many cellular components such as fatty acids, DNA, and proteins. This damage is implicated in many disease pathologies including cancer and neurodegenerative and cardi
Externí odkaz:
https://doaj.org/article/84e81fc151a54ca3bb8ab2e9bcd1e891
Autor:
Justin W. Hines, Naresh Damuka, Jaya Prabhakaran, J. S. Dileep Kumar, Kiran Kumar Solingapuram Sai, Steven J. Kridel, J. John Mann, Akiva Mintz
Publikováno v:
International Journal of Pharmacy and Pharmaceutical Sciences. :43-47
Objective: The objective of this study was to evaluate the uptake and specificity of [11C]MPC-6827, a MT targeted PET ligand in prostate, glioblastoma and breast cancer cells. Methods: [11C]MPC-6827 was synthesized by reacting corresponding desmethyl
Autor:
J.V. Shanmukha Kumar, Kiran Kumar Solingapuram Sai, Sriram Devanathan, Omsai Kotireddy Meka, Skylar Norman, Akiva Mintz, Cristina M. Furdui, Gagan Deep, Justin W. Hines, Nagaraju Bashetti, Xiaofei Chen
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-10 (2019)
EJNMMI Research
EJNMMI Research
Background Reactive oxygen species (ROS)-induced oxidative stress damages many cellular components such as fatty acids, DNA, and proteins. This damage is implicated in many disease pathologies including cancer and neurodegenerative and cardiovascular
Autor:
Meghana Dodda, Akiva Mintz, Naresh Damuka, J. John Mann, Jaya Prabhakaran, Kiran Kumar Solingapuram Sai, J. S. Dileep Kumar, Skylar Norman, Justin W. Hines
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 30:126785
Altered dynamics of microtubules (MT) are implicated in the pathophysiology of a number of brain diseases. Therefore, radiolabeled MT targeted ligands that can penetrate the blood brain barrier (BBB) may offer a direct and sensitive approach for diag