Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Justin Vijay Louis"'
Autor:
Isabelle Landrieu, Caroline Smet-Nocca, Laziza Amniai, Justin Vijay Louis, Jean-Michel Wieruszeski, Jozef Goris, Veerle Janssens, Guy Lippens
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21521 (2011)
Tau phosphorylation and dephosphorylation regulate in a poorly understood manner its physiological role of microtubule stabilization, and equally its integration in Alzheimer disease (AD) related fibrils. A specific phospho-pattern will result from t
Externí odkaz:
https://doaj.org/article/21141210c88a435cac1fad79244717ea
Autor:
Amira Abdel Motaal, Yahya I. Asiri, Heba Handoussa, Kumar Venkatesan, Helmi Alboushnak, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Justin Vijay Louis, Abdullatif Bin Muhsinah, Abdulrhman Alsayari, Narasimman Gurusamy, Kamel A. Saleh, Sivakumar Annadurai, Ali A. Shati
Publikováno v:
Molecules
Volume 25
Issue 2
Molecules, Vol 25, Iss 2, p 418 (2020)
Volume 25
Issue 2
Molecules, Vol 25, Iss 2, p 418 (2020)
Kleinia pendula (Forssk.) DC. is a prostrate or pendent dark green succulent herb found in the southwestern mountain regions of Saudi Arabia. The literature survey of the plant reveals a lack of phytochemical and pharmacological studies, although tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8172ad7b21cf8a6e58b1e74429bfe6
Autor:
Justin Vijay Louis, Kumaran Dandapani, Susheel J. Nara, Yang Hong, Yung Tian, Sarat Kumar Sarvasiddhi, Yifeng Lu, Carolyn Diane Dzierba, Walter Kostich, Yu-Wen Li, Rick L. Pieschl, Sreenivasulu Naidu, Charlie F. Albright, Joanne J. Bronson, John E. Macor, Reeba K. Vikramadithyan
Publikováno v:
Neuropharmacology. 118:167-174
Adaptor-associated kinase 1 (AAK1), a member of the Ark1/Prk1 family of serine/threonine kinases, plays a role in modulating clatherin coated endocytosis of specific surface receptors. We have demonstrated that AAK1 inhibitors are efficacious in rode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f168813c715e6b8c8865371b20f68a5c
https://doi.org/10.1016/j.neuropharm.2017.03.015
https://doi.org/10.1016/j.neuropharm.2017.03.015
Autor:
James E. Grace, Brian Zambrowicz, Pradeep Vattikundala, Kenneth G. Carson, Jonathan Lippy, Clotilde Bourin, Alan Main, Alan Wilson, Sreenivasulu Naidu, Sandhya Mandlekar, Carolyn Diane Dzierba, Saravanan Elavazhagan, Walter Kostich, Gauri Shankar, Jeffrey M. Brown, Charles M. Conway, Charles F. Albright, Justin Vijay Louis, Yu-Wen Li, Vivek Sharma, Yanling Huang, Laszlo Kiss, Amr Nouraldeen, Susheel J. Nara, Martin A. Lewis, Ryan Westphal, Vinay K. Holenarsipur, Anand Balakrishnan, Amy Easton, Robert Zaczek, Jonathan C. Swaffield, Ted Molski, Rick L. Pieschl, Kevin Baker, Katerina Savelieva, Yingzhi Bi, Kenneth S. Santone, Linda J. Bristow, John E. Macor, Jianlin Feng, Guilan Ye, Joanne J. Bronson, Manish Lal Das, Reeba K. Vikramadithyan, Kevin O’Malley, Jason W. Allen, Brian D. Hamman, Michael Gulianello, Yifeng Lu, Thomas H. Lanthorn, Kimberley A. Lentz, Anoop Kumar, Manoj Dokania, Kumaran Dandapani, Rex Denton
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics
To identify novel targets for neuropathic pain, 3097 mouse knockout lines were tested in acute and persistent pain behavior assays. One of the lines from this screen, which contained a null allele of the adapter protein-2 associated kinase 1 (AAK1) g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b1480bd30607a9fe64d0e01fbd6b27
http://europepmc.org/articles/PMC4998676
http://europepmc.org/articles/PMC4998676
Autor:
Durga Shiva Prasad, Rick L. Pieschl, Yu-Wen Li, Siva Subramani, Muppana V. Sreedhara, Shailesh Dudhgaonkar, B.N. Srikumar, Reeba K. Vikramadithyan, Ratika Srivastava, Manish Lal Das, Justin Vijay Louis, Narasimharaju Kalidindi, Mahesh Paschapur, Bharath Adepu, Manjunath Ramarao, Pattipati S. Naidu, Linda J. Bristow, Vijaya K. Kuchibhotla, Jignesh Nagar
Publikováno v:
Journal of psychopharmacology (Oxford, England). 33(1)
Background: A significant proportion of patients suffering from major depression fail to remit following treatment and develop treatment-resistant depression. Developing novel treatments requires animal models with good predictive validity. MRL/lpr m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9d4dcf1d509283d7a23a4993aa30fe
https://pubmed.ncbi.nlm.nih.gov/30484737
https://pubmed.ncbi.nlm.nih.gov/30484737
Autor:
Mohammed Ghazwani, Dalia Almaghaslah, Yahya Alhamhoom, Narasimman Gurusamy, Justin Vijay Louis, Abdulrahman Alsayari
Publikováno v:
Biomedical Research. 29
Background: Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest in the usual activities. According to WHO, depression has been estimated to affect up to 21% of the world's population, while two recent cross-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f451c79beaec06eedca2b881b4396c34
https://doi.org/10.4066/biomedicalresearch.29-18-489
https://doi.org/10.4066/biomedicalresearch.29-18-489
Autor:
Yana Hoorne, Jonathan Crowther, Justin Vijay Louis, Xavier Sagaert, Veerle Janssens, Anna Sablina, Ward Sents, Caroline Lambrecht, Louis Libbrecht, Patrick Pauwels
Publikováno v:
Oncogene
Protein Phosphatase 2A (PP2A) enzymes counteract diverse kinase-driven oncogenic pathways and their function is frequently impaired in cancer. PP2A inhibition is indispensable for full transformation of human cells, but whether loss of PP2A is suffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856cb37287891b1f3e00239df46aadec
https://pubmed.ncbi.nlm.nih.gov/28967903
https://pubmed.ncbi.nlm.nih.gov/28967903
Autor:
Veerle Janssens, Ellen Martens, Justin Vijay Louis, Sari Longin, Evelien Rondelez, Jozef Goris, Karen Zwaenepoel
Publikováno v:
Experimental Cell Research. 314:68-81
Reversible methylation of the protein phosphatase 2A catalytic subunit (PP2A(C)(1)) is an important regulatory mechanism playing a crucial role in the selective recruitment of regulatory B subunits. Here, we investigated the subcellular localization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd9d9f375ebdccbe63ac4e515f703e53
https://doi.org/10.1016/j.yexcr.2007.07.030
https://doi.org/10.1016/j.yexcr.2007.07.030
Autor:
Karen Zwaenepoel, Sari Longin, Veerle Janssens, Justin Vijay Louis, Jozef Goris, Stephen M. Dilworth
Publikováno v:
Journal of Biological Chemistry. 282:26971-26980
Protein phosphatase 2A (PP2A) is a family of multifunctional serine/threonine phosphatases all composed of a catalytic C, a structural A, and a regulatory B subunit. Assembly of the complex with the appropriate B subunit forms the key to the function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0f7fa3a94c3bb9121f946de1da7b52
https://doi.org/10.1074/jbc.m704059200
https://doi.org/10.1074/jbc.m704059200
Autor:
Senthil Murugesan, Yu-Wen Li, Ravi Kumar Trivedi, Rajbharan Yadav, Justin Vijay Louis, K. Vijaya Kumar, Manish Lal Das, Durga Shiva Prasad, Linda J. Bristow, Reeba K. Vikramadithyan, Muppana V. Sreedhara, Anjuman Rudra, Pattipati S. Naidu, T. Siva Subramani
Publikováno v:
Brain, behavior, and immunity. 42
Preclinical studies have shown that administration of Bacillus Calmette-Guerin (BCG) vaccine induces depression-like behaviors in mice; however, the effect of antidepressant drug treatment has not been reported earlier. In the present study, we induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a55d6d8949c6082d80cf1e1b8a60a6e
https://pubmed.ncbi.nlm.nih.gov/25016199
https://pubmed.ncbi.nlm.nih.gov/25016199