Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Justin T. Tvetan"'
Autor:
Alan M. Allgeier, Krishnakumar Ranganathan, Seb Caille, Sheng Cui, Andrew Cosbie, Jacqueline C. S. Woo, Steven M. Mennen, Oliver R. Thiel, Shawn D. Walker, Justin T. Tvetan, Seth Huggins, Neil F. Langille, Richard D. Crockett, Xianqing Shi, Karl B. Hansen, Charles Bernard, Kyle Quasdorf, Fang Wang, Alexander Muci, Bradley P Morgan, Philipp Roosen, Steven Wu, Henry Morrison, Tiffany L. Correll, Margaret M. Faul, Karthik Nagapudi
Publikováno v:
Organic Process Research & Development. 23:1558-1567
The development of a factory process to manufacture the novel cardiac myosin activator omecamtiv mecarbil (1) is described. Omecamtiv mecarbil is prepared via the convergent synthesis and coupling ...
Autor:
Scott W. Roberts, Stephen M. Shaw, Joe Tomaskevitch, Oliver R. Thiel, Dawn E. Cohen, Justin T. Tvetan, Jacqueline E. Milne
Publikováno v:
Organic Process Research & Development. 16:2058-2063
The Ritter reaction utilizing tert-butyl acetate as the tert-butyl cation source was investigated by in situ FTIR and calorimetry under various reaction conditions. It was established that, when a batch mode reaction in acetic acid was performed, min