Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Justin T. O'neal"'
Autor:
Song Hee Lee, Eui Ho Kim, Justin T. O’neal, Gordon Dale, David J. Holthausen, James R. Bowen, Kendra M. Quicke, Ioanna Skountzou, Shyla Gopal, Sanil George, Jens Wrammert, Mehul S. Suthar, Joshy Jacob
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Zika virus (ZIKV) has emerged as a serious health threat in the Americas and the Caribbean. ZIKV is transmitted by the bite of an infected mosquito, sexual contact, and blood transfusion. ZIKV can also be transmitted to the developing fetus
Externí odkaz:
https://doaj.org/article/1222b054c19b4f9b953994df1b0439c9
Autor:
Robert C. Kauffman, Taufiqur R. Bhuiyan, Rie Nakajima, Leslie M. Mayo-Smith, Rasheduzzaman Rashu, Mohammad Rubel Hoq, Fahima Chowdhury, Ashraful Islam Khan, Atiqur Rahman, Siddhartha K. Bhaumik, Levelle Harris, Justin T. O'Neal, Jessica F. Trost, Nur Haq Alam, Algis Jasinskas, Emmanuel Dotsey, Meagan Kelly, Richelle C. Charles, Peng Xu, Pavol Kováč, Stephen B. Calderwood, Edward T. Ryan, Phillip L. Felgner, Firdausi Qadri, Jens Wrammert, Jason B. Harris
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT We characterized the acute B cell response in adults with cholera by analyzing the repertoire, specificity, and functional characteristics of 138 monoclonal antibodies (MAbs) generated from single-cell-sorted plasmablasts. We found that the
Externí odkaz:
https://doaj.org/article/545c93248a4d4ab2b5a66d76c072274b
Autor:
Steven E. Bosinger, Nirav B. Patel, Amit A. Upadhyay, Mehul S. Suthar, Amber N. Wolabaugh, Justin T. O’Neal
Publikováno v:
Journal of Virology. 93
West Nile virus (WNV) is a neurotropic mosquito-borne flavivirus of global importance. Neuroinvasive WNV infection results in encephalitis and can lead to prolonged neurological impairment or death. Type I interferon (IFN-I) is crucial for promoting
Autor:
Circe E. McDonald, Huailiang Ma, Augustine Rajakumar, Jens Wrammert, Mehul S. Suthar, Rana Chakraborty, James R. Bowen, Bali Pulendran, Erica L Johnson, Bassam H. Rimawi, Justin T. O’Neal, Raymond F. Schinazi, Kendra M. Quicke
Publikováno v:
Cell Host & Microbe. 20:83-90
The recent Zika virus (ZIKV) outbreak in Brazil has been directly linked to increased cases of microcephaly in newborns. Current evidence indicates that ZIKV is transmitted vertically from mother to fetus. However, the mechanism of intrauterine trans
Autor:
Erica L Johnson, Nitin Arora, Robert C. Kauffman, Lisa B. Haddad, Mehul S. Suthar, Emery Register, Matthew G. Zimmerman, Carolyn B. Coyne, Kendra M. Quicke, Jens Wrammert, Rana Chakraborty, Oluwaseyi Adekunle, Lalita Priyamvada, Sarah Cordes, Justin T. O’Neal, Deepa Machiah, Dominika Swieboda
Zika virus (ZIKV), which emerged in regions endemic to dengue virus (DENV), is vertically transmitted and results in adverse pregnancy outcomes. Antibodies to DENV can cross-react with ZIKV, but whether these antibodies influence ZIKV vertical transm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be66eca0262766037b7dc1c2314b6700
https://europepmc.org/articles/PMC6394860/
https://europepmc.org/articles/PMC6394860/
Autor:
Steven E. Bosinger, Nirav B. Patel, Amit A. Upadhyay, Mehul S. Suthar, Amber N. Wolabaugh, Justin T. O’Neal
West Nile virus (WNV) is a neurotropic mosquito-borne flavivirus of global importance. Neuroinvasive WNV infection results in encephalitis and can lead to prolonged neurological impairment or death. Type I interferon (IFN-I) is crucial for promoting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7710088d7c3aaa5a390b236cf1b49509
Autor:
Jakob Habib, Varian K. Bailey, Damien A. Fair, David I. Watkins, Maria C. Alvarado, Circe E. McDonald, Jens Wrammert, Joyce Cohen, Justin T. O’Neal, Mehul S. Suthar, Maud Mavigner, Eric Feczko, Eric Earl, Thomas H. Vanderford, Xiaodong Zhang, Jessica Raper, Sanjeev Gumber, David H. O’Connor, Diogo M. Magnani, Sherrie Jean, Guido Silvestri, Ann Chahroudi, Siddhartha Kumar Bhaumik, Mark W. Burke, Mar M. Sanchez, Victoria Avanzato, Zsofia Kovacs-Balint, Martin Styner, Cameron Mattingly, R. Paul Johnson
Publikováno v:
Science Translational Medicine. 10
The Zika virus (ZIKV) epidemic is associated with fetal brain lesions and other serious birth defects classified as congenital ZIKV syndrome. Postnatal ZIKV infection in infants and children has been reported; however, data on brain anatomy, function
Autor:
Nur Haq Alam, Stephen B. Calderwood, Jens Wrammert, Mohammad Rubel Hoq, Rie Nakajima, Firdausi Qadri, Rasheduzzaman Rashu, Meagan Kelly, Justin T. O’Neal, Pavol Kováč, Atiqur Rahman, Jason B. Harris, Edward T. Ryan, Siddhartha Kumar Bhaumik, Peng Xu, Algis Jasinskas, Leslie M. Mayo-Smith, Ashraful Islam Khan, Fahima Chowdhury, Taufiqur Rahman Bhuiyan, Emmanuel Y. Dotsey, Levelle D. Harris, Richelle C. Charles, Robert C. Kauffman, Phillip L. Felgner, Jessica F. Trost
Publikováno v:
mBio
mBio, vol 7, iss 6
mBio, Vol 7, Iss 6, p e02021-16 (2016)
mBio, Vol 7, Iss 6 (2016)
mBio, vol 7, iss 6
mBio, Vol 7, Iss 6, p e02021-16 (2016)
mBio, Vol 7, Iss 6 (2016)
We characterized the acute B cell response in adults with cholera by analyzing the repertoire, specificity, and functional characteristics of 138 monoclonal antibodies (MAbs) generated from single-cell-sorted plasmablasts. We found that the cholera-i
Autor:
James R. Bowen, Mehul S. Suthar, Bali Pulendran, Kendra M. Quicke, Vinita Puri, Circe E. McDonald, Mohan S. Maddur, Reed S. Shabman, Nadia Fedorova, Justin T. O’Neal
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006164 (2017)
PLoS Pathogens
PLoS Pathogens
Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that is causally linked to severe neonatal birth defects, including microcephaly, and is associated with Guillain-Barre syndrome in adults. Dendritic cells (DCs) are an important cell type du