Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Justin T. Low"'
Publikováno v:
Advances in Radiation Oncology, Vol 7, Iss 1, Pp 100814- (2022)
Externí odkaz:
https://doaj.org/article/9de0254fe9024e9082333a34575ad363
Publikováno v:
Current Neurology and Neuroscience Reports. 22:413-425
Leptomeningeal disease (LMD) is a rare, late complication of systemic cancer and is associated with significant neurological morbidity and high mortality. Here we provide an overview of this condition, summarizing key recent research findings and cli
Autor:
Justin T Low, Quinn T Ostrom, Gino Cioffi, Corey Neff, Kristin A Waite, Carol Kruchko, Jill S Barnholtz-Sloan
Publikováno v:
Neurooncol Pract
Background The Central Brain Tumor Registry of the United States (CBTRUS) contains information on all primary brain and other central nervous system (CNS) tumors diagnosed in the United States (US). Here we summarize the 2021 CBTRUS annual statistica
Autor:
Alexander Yuile, Mustafa Khasraw, Justin T Low, Kyle M Walsh, Eric Lipp, Joanne Sy, Laveniya Satgunaseelan, Marina Ann Kastelan, Madhawa De Silva, Adrian Lee, Helen Wheeler
Publikováno v:
Neurooncol Pract
Background Histone mutant gliomas (HMG) with histone H3 K27 and G34 mutations are recognized as biologically discrete entities with distinct anatomical locations, younger age at presentation (in comparison to the most common high-grade gliomas, IDH w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6315d20a2d72e802ff7b236e150806
https://europepmc.org/articles/PMC9665055/
https://europepmc.org/articles/PMC9665055/
Autor:
Stephen T. Keir, Heng Liu, Justin T. Low, Christopher J. Pirozzi, Nathan Reynolds, Eric S. Lipp, Annick Desjardins, Henry S. Friedman, Mustafa Khasraw, Darell D. Bigner, David M. Ashley, Matthew S. Waitkus
Publikováno v:
Cancer Research. 83:4924-4924
Glioblastoma (GBM), the most common primary malignant brain tumor in adults, is an incurable disease that has an inevitable tendency to recur following standard of care surgery, radiotherapy, and temozolomide chemotherapy. There is an urgent need for
Autor:
Justin T. Low, Vidyalakshmi Chandramohan, Michelle L. Bowie, Michael C. Brown, Matthew S. Waitkus, Aaron Briley, Kevin Stevenson, Rebecca Fuller, Zachary J. Reitman, Andrea M. Muscat, Seethalakshmi Hariharan, Janell Hostettler, Sarah Danehower, Ali Baker, Mustafa Khasraw, Nicholas C. Wong, Simon Gregory, Smita K. Nair, Amy Heimberger, Matthias Gromeier, Darell D. Bigner, David M. Ashley
Publikováno v:
Cancer cell. 40(5)
Autor:
Shashwat Tripathi, Hinda Najem, Akanksha Sanjay Mahajan, Peng Zhang, Justin T Low, Alexander H Stegh, Michael A Curran, David M Ashley, Charles David James, Amy B Heimberger
Publikováno v:
F1000Research. 11:1010
Median survival of patients with glioblastoma (GBM) treated with standard of care which consists of maximal safe resection of the contrast-enhancing portion of the tumor followed by radiation therapy with concomitant adjuvant temozolomide (TMZ) remai
Autor:
Robert J. Gorelick, Pablo García-Miranda, Kevin M. Weeks, Justin T. Low, Samuel E. Butcher, Kathryn D. Mouzakis
Publikováno v:
Biochemistry
The HIV-1 ribosomal frameshift element is highly structured, regulates translation of all virally encoded enzymes, and is a promising therapeutic target. The prior model for this motif contains two helices separated by a three-nucleotide bulge. Modif
Autor:
J. Kevin Ramer, Zoey L. Fredericks, Rainer Blaesius, Ekaterina S. Lobanova, David P. Siderovski, Justin T. Low, Alexander S. Shavkunov, Vadim Y. Arshavsky, Francis S. Willard, Brian Kuhlman, Christopher A. Johnston
Publikováno v:
Biochemistry. 45:11390-11400
G-proteins cycle between an inactive GDP-bound state and an active GTP-bound state, serving as molecular switches that coordinate cellular signaling. We recently used phage display to identify a series of peptides that bind G alpha subunits in a nucl
Autor:
Joseph M Watts, Olivier ter Brake, Justin T. Low, Kevin M. Weeks, Stefanie A Knoepfel, Ben Berkhout
Publikováno v:
Molecular therapy, 20(4), 820-828. Nature Publishing Group
The RNA interference (RNAi) pathway can be exploited using short hairpin RNAs (shRNAs) to durably inactivate pathogenic genes. Prediction of optimal target sites is notoriously inaccurate and current approaches applied to HIV-1 show weak correlations