Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Justin T. J. Spence"'
Autor:
Andrei S. Baluna, Albano Galan, David A. Leigh, Gareth D. Smith, Justin T. J. Spence, Daniel J. Tetlow, Iñigo J. Vitorica-Yrezabal, Min Zhang
Publikováno v:
Journal of the American Chemical Society. 145:9825-9833
Autor:
Chong Tian, Daniel J. Tetlow, Malcolm A. Y. Gall, Javier Echavarren, Justin T J Spence, David A. Leigh, Adrian Haertsch
Publikováno v:
Journal of the American Chemical Society
We report on the preparation of a decapeptide through the parallel operation of two rotaxane-based molecular machines. The synthesis proceeds in four stages: (1) simultaneous operation of two molecular peptide synthesizers in the same reaction vessel
Publikováno v:
Angewandte Chemie (International ed. in English). 55(35)
Hyperjapones A-E and hyperjaponols A-C are complex natural products of mixed aromatic polyketide and terpene biosynthetic origin that have recently been isolated from Hypericum japonicum. We have synthesized hyperjapones A-E using a biomimetic, oxida
Publikováno v:
Organic letters. 17(24)
The total synthesis of peniphenones A-D has been achieved via Michael reactions between appropriate nucleophiles and a common o-quinone methide intermediate. This strategy, which was based on a biosynthetic hypothesis, minimized the use of protecting
Publikováno v:
Organic Letters. 13:5318-5321
A structure revision for the recently isolated fungal meroterpenoids, cytosporolides A-C, is suggested based on biosynthetic speculation and reinterpretation of existing spectroscopic data. The structure revision is supported by a biomimetic syntheti
Publikováno v:
Organicbiomolecular chemistry. 12(15)
Protected cyclohexanol and cyclohex-2-enol substrates, containing benzyl ether and benzoate ester moieties, were designed to fit into the active site of the Tyr96Ala mutant of cytochrome P450cam. The protected cyclohexanol substrates were efficiently
Publikováno v:
Organic letters. 15(15)
The total synthesis of ent-penilactone A and penilactone B has been achieved via biomimetic Michael reactions between tetronic acids and o-quinone methides. A five-component cascade reaction between a tetronic acid, formaldehyde, and a resorcinol der
Publikováno v:
Organic Letters; Oct2011, Vol. 13 Issue 19, p5318-5321, 4p