Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Justin T Proto"'
Autor:
Stacie L. Bulfer, Bertrand Le Bourdonnec, Jeffery D. Zwicker, Yu Mi Ahn, Gada Al-Ani, Hikmat Al-Hashimi, Chase Crawley, Kristin M. Elliott, Saqib Faisal, Andrew M. Harned, Cale L. Heiniger, Molly M. Hood, Salim Javed, Michael Kennedy, Joshua W. Large, Cynthia B. Leary, Wei-Ping Lu, Kylie Luther, Max D. Petty, Hunter R. Picard, Justin T. Proto, Yeni K. Romero, Forrest A. Stanley, Kristen L. Stoltz, Daniel C. Tanner, Hanumaiah Telikepalli, Mary J. Timson, Lakshminarayana Vogeti, Subha Vogeti, Sihyung Yang, Lexy H. Zhong, Bryan D. Smith, Daniel L. Flynn
Publikováno v:
Cancer Research. 83:4045-4045
Background: Mutations in the RAS/MAPK pathway are a frequent driver of cancer, with oncogenic RAS or RAF mutations occurring in >30% of all cancers. First generation BRAF inhibitors are approved for use for tumors with Class I BRAF mutations (V600X).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebf3a2336f0156e37e4810fe4bbdbdd5
https://doi.org/10.1158/1538-7445.am2023-4045
https://doi.org/10.1158/1538-7445.am2023-4045
Autor:
Bryan D. Smith, Lakshminarayana Vogeti, Quanrong Shen, Cynthia B. Leary, Chase K Crawley, Karen M. Yates, Cale L Heiniger, Hikmat Al-Hashimi, Timothy M. Caldwell, Anu Gupta, Mary J Timson, Hanumaiah Telikepalli, Justin T Proto, Daniel L. Flynn, Gada Al-Ani, Subha Vogeti, Wei-Ping Lu, Jarnail Singh, Yu Mi Ahn, Stacie L. Bulfer
Publikováno v:
Molecular Cancer Therapeutics. 18:B129-B129
Background: Cancer cells activate autophagy, a catabolic process to resupply nutrients and recycle damaged organelles, in order to survive stresses such as limited nutrients and hypoxia, or chemotherapy treatments. RAS mutant cancers, in particular,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5054904b7c6bc718908e801bc3f9ad2b
https://doi.org/10.1158/1535-7163.targ-19-b129
https://doi.org/10.1158/1535-7163.targ-19-b129
Publikováno v:
Organic letters. 19(7)
Using an intramolecular didehydro-Diels–Alder reaction, ene–yne substituted pyrroles, thiophenes, and furans afford functionalized indoles, benzothiophenes, and benzofurans and the corresponding dihydroaromatic products. Product selectivity for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9496b5a69db262d492301d0843a048c
https://pubmed.ncbi.nlm.nih.gov/28267342
https://pubmed.ncbi.nlm.nih.gov/28267342