Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Justin Saul"'
Autor:
Ileana Lorenzini, Eric Alsop, Jennifer Levy, Lauren M. Gittings, Deepti Lall, Benjamin E. Rabichow, Stephen Moore, Ryan Pevey, Lynette M. Bustos, Camelia Burciu, Divya Bhatia, Mo Singer, Justin Saul, Amanda McQuade, Makis Tzioras, Thomas A. Mota, Amber Logemann, Jamie Rose, Sandra Almeida, Fen-Biao Gao, Michael Marks, Christopher J. Donnelly, Elizabeth Hutchins, Shu-Ting Hung, Justin Ichida, Robert Bowser, Tara Spires-Jones, Mathew Blurton-Jones, Tania F. Gendron, Robert H. Baloh, Kendall Van Keuren-Jensen, Rita Sattler
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
While motor and cortical neurons are affected in C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD), it remains largely unknown if and how non-neuronal cells induce or exacerbate neuronal damage. We differentiated C9orf72 ALS
Externí odkaz:
https://doaj.org/article/c5861f14d9984d6d91846ead3941a04a
Autor:
Emily Goel, Megan Erwin, Claire V. Cawthon, Carson Schaff, Nathaniel Fedor, Trevor Rayl, Onree Wilson, Uwe Christians, Thomas C. Register, Randolph L. Geary, Justin Saul, Saami K. Yazdani
Publikováno v:
Molecules, Vol 25, Iss 7, p 1596 (2020)
Background: Drug-coated balloons (DCBs), which deliver anti-proliferative drugs with the aid of excipients, have emerged as a new endovascular therapy for the treatment of peripheral arterial disease. In this study, we evaluated the use of keratose (
Externí odkaz:
https://doaj.org/article/72e95fbad5a44554b6b9a86671e477c7
Autor:
Yanyang Tang, David Lowry, Nirupa Nagaratnam, Ji Qiu, Jose M. Martin-Garcia, Hao Hu, Chufeng Li, Sahba Zaare, Justin Saul, Petra Fromme, John C. H. Spence, Uwe Weierstall, Sabine Botha, Joshua LaBaer, Nadia A. Zatsepin, Mark S. Hunter
Publikováno v:
Acta Crystallographica. Section F, Structural Biology Communications
The first SFX diffraction from EGFP-μNS(448–605) crystals led to initial electron-density maps that allowed the clear identification of two EGFP molecules as well as of electron density for μNS(448–605). Determining the crystal structure of μN
Autor:
Erik Brodin, Melanie Boehmer, Alexandra Prentice, Emily Neff, Kathleen McCoy, Jens Mueller, Justin Saul, Jessica L Sparks
Publikováno v:
Biomedical materials (Bristol, England). 17(5)
Keratins are a class of intermediate filament proteins that can be obtained from numerous sources including human hair. Materials fabricated from keratins offer desirable characteristics as scaffolds for tissue engineering, including intrinsic cell a
Autor:
Ileana Lorenzini, Eric Alsop, Jennifer Levy, Lauren M Gittings, Deepti Lall, Benjamin E Rabichow, Stephen Moore, Ryan Pevey, Lynette Bustos, Camelia Burciu, Divya Bhatia, Mo Singer, Justin Saul, Amanda McQuade, Makis Tzioras, Thomas A Mota, Amber Logemann, Jamie Rose, Sandra Almeida, Fen-Biao Gao, Michael Marks, Christopher J Donnelly, Elizabeth Hutchins, Shu-Ting Hung, Justin Ichida, Robert Bowser, Tara Spires-Jones, Mathew Blurton-Jones, Tania F Gendron, Robert H Baloh, Kendall Van Keuren-Jensen, Rita Sattler
Background A mutation in the C9orf72 gene is the most common genetic mutation of familial and sporadic ALS, as well as familial FTD. While prior studies have focused on elucidating the mechanisms of neuronal dysfunction and neurodegeneration associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ed9356d12a0c4f704bd87027f5bc041
https://doi.org/10.1101/2020.09.03.277459
https://doi.org/10.1101/2020.09.03.277459
Autor:
Justin Saul, Joshua LaBaer, Ji Qiu, Petra Fromme, Yanyang Tang, Nirupa Nagaratnam, Jose M. Martin-Garcia
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Baculovirus mediated-insect cell expression systems have been widely used for producing heterogeneous proteins. However, to date, there is still the lack of an easy-to-manipulate system that enables the high-throughput protein characterization in ins
Autor:
Joshua LaBaer, Howard C. Hang, Kristi Barker, M. Ramona Neunuebel, Matthias P. Machner, Morgan Graves, Justin Saul, Ji Qiu, Nathan P. Westcott, Xiaobo Yu, Kimberly Baxter Decker
Publikováno v:
Journal of Proteome Research. 14:1920-1936
Host-pathogen protein interactions are fundamental to every microbial infection, yet their identification has remained challenging due to the lack of simple detection tools that avoid abundance biases while providing an open format for experimental m
Autor:
Joshua LaBaer, Lerys del Moral, Jin Park, James M. Pipas, Xiaobo Yu, Jie Wang, Michael Fiacco, Ji Qiu, Lusheng Song, Andrea Throop, Xiaofang Bian, Preston Hunter, Jason Steel, Catherine Seiler, Justin Saul
Publikováno v:
Theranostics
Throughout the long history of virus-host co-evolution, viruses have developed delicate strategies to facilitate their invasion and replication of their genome, while silencing the host immune responses through various mechanisms. The systematic char
Autor:
Justin Saul, Karen S. Anderson, Jie Wang, Xiaobo Yu, Ji Qiu, Garrick Wallstrom, Joshua LaBaer, Xiaofang Bian, Kristi Barker, Jonine D. Figueroa, Fernanda Festa, Jason Steel, Jin Park
Publikováno v:
PROTEOMICS - Clinical Applications. 7:378-383
Purpose We aim to develop a protein microarray platform capable of presenting both natural and denatured forms of proteins for antibody biomarker discovery. We will further optimize plasma screening protocols to improve detection. Experimental design
Autor:
Justin, Saul, Brianne, Petritis, Sujay, Sau, Femina, Rauf, Michael, Gaskin, Benjamin, Ober-Reynolds, Irina, Mineyev, Mitch, Magee, John, Chaput, Ji, Qiu, Joshua, LaBaer
Publikováno v:
Protein science : a publication of the Protein Society. 23(8)
There are many proteomic applications that require large collections of purified protein, but parallel production of large numbers of different proteins remains a very challenging task. To help meet the needs of the scientific community, we have deve