Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Justin S. Lafountaine"'
Autor:
Justin S. LaFountaine, Robert O. Williams, Leena Kumari Prasad, Dave A. Miller, James W. McGinity
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 113:157-167
The oral delivery of mucoadhesive patches has been shown to enhance the absorption of large molecules such as peptides. We hypothesized that this mechanism could have utility for poorly soluble small molecules by utilizing a mucoadhesive polymer as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7dec0179f5ed397fadfa5decc4ea441
https://doi.org/10.1016/j.ejpb.2016.12.031
https://doi.org/10.1016/j.ejpb.2016.12.031
Autor:
Dieter Lubda, Robert O. Williams, Chris Brough, Dave A. Miller, James W. McGinity, Justin S. LaFountaine, Leena Kumari Prasad, Scott V. Jermain
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 101:72-81
Polyvinyl alcohol has received little attention as a matrix polymer in amorphous solid dispersions (ASDs) due to its thermal and rheological limitations in extrusion processing and limited organic solubility in spray drying applications. Additionally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b19b126456cf5c72884191cbd6a1750
https://doi.org/10.1016/j.ejpb.2016.01.018
https://doi.org/10.1016/j.ejpb.2016.01.018
Autor:
Robert O. Williams, Julien Maincent, Justin M. Keen, Leena Kumari Prasad, Justin S. LaFountaine, James W. McGinity
Publikováno v:
Journal of Drug Delivery Science and Technology. 30:501-510
An electrostatic powder deposition (ESPD) method was developed to prepare free films for drug delivery. Films were prepared using polyethylene oxide (PEO), a physical mixture of PEO and acetaminophen (APAP), and co-processed PEO and APAP particles. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::344d05f947af72304565063d1d51347e
https://doi.org/10.1016/j.jddst.2015.08.011
https://doi.org/10.1016/j.jddst.2015.08.011
Autor:
Dave A. Miller, Robert O. Williams, Chris Brough, Justin S. LaFountaine, James W. McGinity, Leena Kumari Prasad
Publikováno v:
AAPS PharmSciTech. 17:120-132
Thermal processing technologies continue to gain interest in pharmaceutical manufacturing. However, the types and grades of polymers that can be utilized in common thermal processing technologies, such as hot-melt extrusion (HME), are often limited b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acaea5458cf345093df9aad4fb8a09b9
https://doi.org/10.1208/s12249-015-0417-7
https://doi.org/10.1208/s12249-015-0417-7
Publikováno v:
AAPS PharmSciTech. 17:43-55
Thermal processing of amorphous solid dispersions continues to gain interest in the pharmaceutical industry, as evident by several recently approved commercial products. Still, a number of pharmaceutical polymer carriers exhibit thermal or viscoelast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9172c2bf6c4be5324d1d500a48eee4e
https://doi.org/10.1208/s12249-015-0393-y
https://doi.org/10.1208/s12249-015-0393-y
Publikováno v:
AAPS PharmSciTech. 19(5)
The formulation factors relevant to developing immediate and controlled release dosage forms containing poorly soluble drugs dispersed in amorphous systems are poorly understood. While the utility of amorphous solid dispersions is becoming apparent i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e8b8bf837f7733276bb0357fb78fcd
https://pubmed.ncbi.nlm.nih.gov/29192405
https://pubmed.ncbi.nlm.nih.gov/29192405
Autor:
Leena Kumari Prasad, James W. McGinity, Robert O. Williams, Justin S. LaFountaine, Justin M. Keen
Publikováno v:
International journal of pharmaceutics. 515(1-2)
Electrostatic powder deposition (ESPD) has been developed as a solvent-free method to prepare pharmaceutical films. The aim of this work was to investigate the influence of process parameters during (1) electrostatic powder deposition, (2) curing, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68cf31448e3633b27dad0414069ffac
https://pubmed.ncbi.nlm.nih.gov/27725271
https://pubmed.ncbi.nlm.nih.gov/27725271
Publikováno v:
Formulating Poorly Water Soluble Drugs ISBN: 9783319426075
The understanding in design, classification, and characterization of Lipid-Based Formulations (LBFs) has evolved greatly over the last two decades. LBFs include simple lipid solutions, self-emulsifying and self-microemulsifying drug delivery systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67c734a27ec374842d91a0d24656fbff
https://doi.org/10.1007/978-3-319-42609-9_7
https://doi.org/10.1007/978-3-319-42609-9_7
Publikováno v:
International journal of pharmaceutics. 494(1)
In recent years, several new genome editing technologies have been developed. Of these the zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and the CRISPR/Cas9 RNA-guided endonuclease system are the most widely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffced1c3ac4d5f838ea950a6672840f0
https://pubmed.ncbi.nlm.nih.gov/26278489
https://pubmed.ncbi.nlm.nih.gov/26278489
Autor:
Thomas Huddle, Eugene A. White, Alex H. F. Wu, Robert N. Lamb, Justin S. Lafountaine, Jacob W. Coffey, Ronald S. Haines, Hua Zhang, Zhi-Jun Lim, Nam T. Tuong
Publikováno v:
Journal of Chemical Education. 86:365
Superhydrophobic (non water-wettable) surfaces can possess the ability to self-clean (the so-called "lotus effect"). The task of devising the apparatus and method for quantifying this self-cleaning effect was offered as a project in a third-year unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c4dc3e964f43f46b64b3fce3bc83834
https://doi.org/10.1021/ed086p365
https://doi.org/10.1021/ed086p365