Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Justin S Antony"'
Autor:
Michael S D Kormann, Alexander Dewerth, Felizitas Eichner, Praveen Baskaran, Andreas Hector, Nicolas Regamey, Dominik Hartl, Rupert Handgretinger, Justin S Antony
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183526 (2017)
Cystic Fibrosis (CF) is the most common monogenic disease among people of Western European descent and caused by mutations in the CFTR gene. However, the disease severity is immensely variable even among patients with similar CFTR mutations due to th
Externí odkaz:
https://doaj.org/article/2110c9c0729d433c8a0eeaf7724b213e
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 3, p e0003647 (2015)
BACKGROUND:Urinary Schistosomiasis is a neglected tropical disease endemic in many sub Saharan -African countries. Collectin Kidney 1 (CL-K1, encoded by COLEC11 on chromosome 2p25.3), a member of the vertebrate C-type lectin super family, has recentl
Externí odkaz:
https://doaj.org/article/8c89374d797643288c9a29ece433f721
Autor:
Anshuman Mishra, Justin S Antony, Pandarisamy Sundaravadivel, Hoang Van Tong, Christian G Meyer, Reshma D Jalli, Thirumalaisamy P Velavan, Kumarasamy Thangaraj
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125940 (2015)
Visceral leishmaniasis (VL), one of the neglected tropical diseases, is endemic in the Indian subcontinent. Ficolins are circulating serum proteins of the lectin complement system and involved in innate immunity.We have estimated ficolin-2 serum leve
Externí odkaz:
https://doaj.org/article/36d1fd0d929445089858e2eac1a43277
Autor:
Shreyas S. Kuduvalli, Precilla S. Daisy, Anandraj Vaithy, Mugilarasi Purushothaman, Arumugam Ramachandran Muralidharan, Kumar B. Agiesh, Markus Mezger, Justin S. Antony, Madhu Subramani, Biswajit Dubashi, Indrani Biswas, K. P. Guruprasad, T. S. Anitha
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/f3c3571cdb41491d97c71fb551405da6
Autor:
Justin S. Antony, Pascale Birrer, Claudia Bohnert, Sina Zimmerli, Petra Hillmann, Hervé Schaffhauser, Christine Hoeflich, Andreas Hoeflich, Ramzi Khairallah, Andreas T. Satoh, Isabelle Kappeler, Isabel Ferreira, Klaas P. Zuideveld, Friedrich Metzger
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102055- (2023)
Insulin-like growth factor I (IGF-I) is a growth-promoting anabolic hormone that fosters cell growth and tissue homeostasis. IGF-I deficiency is associated with several diseases, including growth disorders and neurological and musculoskeletal disease
Externí odkaz:
https://doaj.org/article/9c7a20e7616f432288f59c0d27bd4194
Autor:
Anne S. Schmitz, Milena Korneck, Janani Raju, Andrés Lamsfus-Calle, Alberto Daniel-Moreno, Justin S. Antony, Markus Mezger, Ludger Schöls, Stefan Hauser, Stefanie N. Hayer
Publikováno v:
Stem Cell Research, Vol 69, Iss , Pp 103066- (2023)
Mutations in Colony-stimulating factor 1 receptor (CSF1R) lead to CSF1R-related leukoencephalopathy, also known as Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), a rapidly progressing neurodegenerative disease with s
Externí odkaz:
https://doaj.org/article/5ce3517f8f9d46daa79177b47aee0bf5
Autor:
Shreyas S. Kuduvalli, Precilla S. Daisy, Anandraj Vaithy, Mugilarasi Purushothaman, Arumugam Ramachandran Muralidharan, Kumar B. Agiesh, Markus Mezger, Justin S. Antony, Madhu Subramani, Biswajit Dubashi, Indrani Biswas, K. P. Guruprasad, T. S. Anitha
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Glioma is the most devastating high-grade tumor of the central nervous system, with dismal prognosis. Existing treatment modality does not provide substantial benefit to patients and demands novel strategies. One of the first-line treatments for glio
Externí odkaz:
https://doaj.org/article/3c4033047c774a5ca8f541c70d155688
Autor:
Tahereh Mohammadian Gol, Guillermo Ureña-Bailén, Yujuan Hou, Ralph Sinn, Justin S. Antony, Rupert Handgretinger, Markus Mezger
Publikováno v:
Frontiers in Genome Editing, Vol 4 (2023)
Blood disorders are a group of diseases including hematological neoplasms, clotting disorders and orphan immune deficiency diseases that affects human health. Current improvements in genome editing based therapeutics demonstrated preclinical and clin
Externí odkaz:
https://doaj.org/article/af6536b6e18e46e6acc0fbb918946857
Autor:
Mezger, Yujuan Hou, Guillermo Ureña-Bailén, Tahereh Mohammadian Gol, Paul Gerhard Gratz, Hans Peter Gratz, Alicia Roig-Merino, Justin S. Antony, Andrés Lamsfus-Calle, Alberto Daniel-Moreno, Rupert Handgretinger, Markus
Publikováno v:
Genes; Volume 13; Issue 12; Pages: 2348
X-linked severe combined immunodeficiency (X-SCID) is a primary immunodeficiency that is caused by mutations in the interleukin-2 receptor gamma (IL2RG) gene. Some patients present atypical X-SCID with mild clinical symptoms due to somatic revertant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::496e7a39b5708de395302caf9566ef15
Somatic Reversion of a Novel IL2RG Mutation Resulting in Atypical X-Linked Combined Immunodeficiency
Autor:
Yujuan Hou, Hans Peter Gratz, Guillermo Ureña-Bailén, Paul G. Gratz, Karin Schilbach-Stückle, Tina Renno, Derya Güngör, Daniel A. Mader, Elke Malenke, Justin S. Antony, Rupert Handgretinger, Markus Mezger
Publikováno v:
Genes, Vol 13, Iss 35, p 35 (2022)
Mutations of the IL2RG gene, which encodes for the interleukin-2 receptor common gamma chain (γC, CD132), can lead to X-linked severe combined immunodeficiency (X-SCID) associated with a T−B+NK− phenotype as a result of dysfunctional γC-JAK3-ST
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::bf9941b84e0ef1f1a485ae4de657f54a
https://www.mdpi.com/2073-4425/13/1/35
https://www.mdpi.com/2073-4425/13/1/35