Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Justin S Antony"'
Autor:
Michael S D Kormann, Alexander Dewerth, Felizitas Eichner, Praveen Baskaran, Andreas Hector, Nicolas Regamey, Dominik Hartl, Rupert Handgretinger, Justin S Antony
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183526 (2017)
Cystic Fibrosis (CF) is the most common monogenic disease among people of Western European descent and caused by mutations in the CFTR gene. However, the disease severity is immensely variable even among patients with similar CFTR mutations due to th
Externí odkaz:
https://doaj.org/article/2110c9c0729d433c8a0eeaf7724b213e
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 3, p e0003647 (2015)
BACKGROUND:Urinary Schistosomiasis is a neglected tropical disease endemic in many sub Saharan -African countries. Collectin Kidney 1 (CL-K1, encoded by COLEC11 on chromosome 2p25.3), a member of the vertebrate C-type lectin super family, has recentl
Externí odkaz:
https://doaj.org/article/8c89374d797643288c9a29ece433f721
Autor:
Anshuman Mishra, Justin S Antony, Pandarisamy Sundaravadivel, Hoang Van Tong, Christian G Meyer, Reshma D Jalli, Thirumalaisamy P Velavan, Kumarasamy Thangaraj
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125940 (2015)
Visceral leishmaniasis (VL), one of the neglected tropical diseases, is endemic in the Indian subcontinent. Ficolins are circulating serum proteins of the lectin complement system and involved in innate immunity.We have estimated ficolin-2 serum leve
Externí odkaz:
https://doaj.org/article/36d1fd0d929445089858e2eac1a43277
Autor:
Shreyas S. Kuduvalli, Precilla S. Daisy, Anandraj Vaithy, Mugilarasi Purushothaman, Arumugam Ramachandran Muralidharan, Kumar B. Agiesh, Markus Mezger, Justin S. Antony, Madhu Subramani, Biswajit Dubashi, Indrani Biswas, K. P. Guruprasad, T. S. Anitha
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/f3c3571cdb41491d97c71fb551405da6
Autor:
Justin S. Antony, Pascale Birrer, Claudia Bohnert, Sina Zimmerli, Petra Hillmann, Hervé Schaffhauser, Christine Hoeflich, Andreas Hoeflich, Ramzi Khairallah, Andreas T. Satoh, Isabelle Kappeler, Isabel Ferreira, Klaas P. Zuideveld, Friedrich Metzger
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102055- (2023)
Insulin-like growth factor I (IGF-I) is a growth-promoting anabolic hormone that fosters cell growth and tissue homeostasis. IGF-I deficiency is associated with several diseases, including growth disorders and neurological and musculoskeletal disease
Externí odkaz:
https://doaj.org/article/9c7a20e7616f432288f59c0d27bd4194
Autor:
Anne S. Schmitz, Milena Korneck, Janani Raju, Andrés Lamsfus-Calle, Alberto Daniel-Moreno, Justin S. Antony, Markus Mezger, Ludger Schöls, Stefan Hauser, Stefanie N. Hayer
Publikováno v:
Stem Cell Research, Vol 69, Iss , Pp 103066- (2023)
Mutations in Colony-stimulating factor 1 receptor (CSF1R) lead to CSF1R-related leukoencephalopathy, also known as Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), a rapidly progressing neurodegenerative disease with s
Externí odkaz:
https://doaj.org/article/5ce3517f8f9d46daa79177b47aee0bf5
Autor:
Tahereh Mohammadian Gol, Miso Kim, Ralph Sinn, Guillermo Ureña-Bailén, Sarah Stegmeyer, Paul Gerhard Gratz, Fatemeh Zahedipour, Alicia Roig-Merino, Justin S. Antony, Markus Mezger
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16065 (2023)
Natural killer (NK) cell immunotherapy has emerged as a novel treatment modality for various cancer types, including leukemia. The modulation of inhibitory signaling pathways in T cells and NK cells has been the subject of extensive investigation in
Externí odkaz:
https://doaj.org/article/ec2bce433d654e6a8b24d14ad72c50b0
Autor:
Shreyas S. Kuduvalli, Precilla S. Daisy, Anandraj Vaithy, Mugilarasi Purushothaman, Arumugam Ramachandran Muralidharan, Kumar B. Agiesh, Markus Mezger, Justin S. Antony, Madhu Subramani, Biswajit Dubashi, Indrani Biswas, K. P. Guruprasad, T. S. Anitha
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Glioma is the most devastating high-grade tumor of the central nervous system, with dismal prognosis. Existing treatment modality does not provide substantial benefit to patients and demands novel strategies. One of the first-line treatments for glio
Externí odkaz:
https://doaj.org/article/3c4033047c774a5ca8f541c70d155688
Autor:
Tahereh Mohammadian Gol, Guillermo Ureña-Bailén, Yujuan Hou, Ralph Sinn, Justin S. Antony, Rupert Handgretinger, Markus Mezger
Publikováno v:
Frontiers in Genome Editing, Vol 4 (2023)
Blood disorders are a group of diseases including hematological neoplasms, clotting disorders and orphan immune deficiency diseases that affects human health. Current improvements in genome editing based therapeutics demonstrated preclinical and clin
Externí odkaz:
https://doaj.org/article/af6536b6e18e46e6acc0fbb918946857
Preclinical Evaluation of CRISPR-Edited CAR-NK-92 Cells for Off-the-Shelf Treatment of AML and B-ALL
Autor:
Guillermo Ureña-Bailén, Jérôme-Maurice Dobrowolski, Yujuan Hou, Alicia Dirlam, Alicia Roig-Merino, Sabine Schleicher, Daniel Atar, Christian Seitz, Judith Feucht, Justin S. Antony, Tahereh Mohammadian Gol, Rupert Handgretinger, Markus Mezger
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12828 (2022)
Acute myeloid leukemia (AML) and B-cell acute lymphocytic leukemia (B-ALL) are severe blood malignancies affecting both adults and children. Chimeric antigen receptor (CAR)-based immunotherapies have proven highly efficacious in the treatment of leuk
Externí odkaz:
https://doaj.org/article/e19ee5436957478ebbfcf82cfb2764bb