Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Justin R. Kulchycki"'
Autor:
H. Josh Jang, Galen Hostetter, Alexander W. Macfarlane, Zachary Madaj, Eric A. Ross, Toshinori Hinoue, Justin R. Kulchycki, Ryan S. Burgos, Mahvish Tafseer, R. Katherine Alpaugh, Candice L. Schwebel, Rutika Kokate, Daniel M. Geynisman, Matthew R. Zibelman, Pooja Ghatalia, Peter W. Nichols, Woonbok Chung, Jozef Madzo, Noah M. Hahn, David I. Quinn, Jean-Pierre J. Issa, Michael J. Topper, Stephen B. Baylin, Hui Shen, Kerry S. Campbell, Peter A. Jones, Elizabeth R. Plimack
Publikováno v:
Clinical Cancer Research. 29:2052-2065
Purpose: On the basis of preclinical evidence of epigenetic contribution to sensitivity and resistance to immune checkpoint inhibitors (ICI), we hypothesized that guadecitabine (hypomethylating agent) and atezolizumab [anti–programmed cell death li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::962fc57340b594baa9ac6bf30e584454
https://doi.org/10.1158/1078-0432.ccr-22-3642
https://doi.org/10.1158/1078-0432.ccr-22-3642
Autor:
Elizabeth R. Plimack, Peter A. Jones, Kerry S. Campbell, Hui Shen, Stephen B. Baylin, Michael J. Topper, Jean-Pierre J. Issa, David I. Quinn, Noah M. Hahn, Jozef Madzo, Woonbok Chung, Peter W. Nichols, Pooja Ghatalia, Matthew R. Zibelman, Daniel M. Geynisman, Rutika Kokate, Candice L. Schwebel, R. Katherine Alpaugh, Mahvish Tafseer, Ryan S. Burgos, Justin R. Kulchycki, Toshinori Hinoue, Eric A. Ross, Zachary Madaj, Alexander W. Macfarlane, Galen Hostetter, H. Josh Jang
Supplementary Figure 12: HLA-DR and NKG2D abundance on peripheral lymphocytes associate with longer progression free survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2889c2c3746168b7bb44dd2dada19b7e
https://doi.org/10.1158/1078-0432.22587063
https://doi.org/10.1158/1078-0432.22587063
Autor:
Elizabeth R. Plimack, Peter A. Jones, Kerry S. Campbell, Hui Shen, Stephen B. Baylin, Michael J. Topper, Jean-Pierre J. Issa, David I. Quinn, Noah M. Hahn, Jozef Madzo, Woonbok Chung, Peter W. Nichols, Pooja Ghatalia, Matthew R. Zibelman, Daniel M. Geynisman, Rutika Kokate, Candice L. Schwebel, R. Katherine Alpaugh, Mahvish Tafseer, Ryan S. Burgos, Justin R. Kulchycki, Toshinori Hinoue, Eric A. Ross, Zachary Madaj, Alexander W. Macfarlane, Galen Hostetter, H. Josh Jang
Purpose:On the basis of preclinical evidence of epigenetic contribution to sensitivity and resistance to immune checkpoint inhibitors (ICI), we hypothesized that guadecitabine (hypomethylating agent) and atezolizumab [anti–programmed cell death lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15863b501539cdcb1e336129965c9e6
https://doi.org/10.1158/1078-0432.c.6571947.v1
https://doi.org/10.1158/1078-0432.c.6571947.v1
Autor:
Elizabeth R. Plimack, Peter A. Jones, Kerry S. Campbell, Hui Shen, Stephen B. Baylin, Michael J. Topper, Jean-Pierre J. Issa, David I. Quinn, Noah M. Hahn, Jozef Madzo, Woonbok Chung, Peter W. Nichols, Pooja Ghatalia, Matthew R. Zibelman, Daniel M. Geynisman, Rutika Kokate, Candice L. Schwebel, R. Katherine Alpaugh, Mahvish Tafseer, Ryan S. Burgos, Justin R. Kulchycki, Toshinori Hinoue, Eric A. Ross, Zachary Madaj, Alexander W. Macfarlane, Galen Hostetter, H. Josh Jang
Supplementary Figure 8: PD-L1 levels in tumor or tumor microenvironment does not associate with tumor progression or control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7a8eb8aff8605de7e80f259eb3a7f2
https://doi.org/10.1158/1078-0432.22587042
https://doi.org/10.1158/1078-0432.22587042
Autor:
Elizabeth R. Plimack, Peter A. Jones, Kerry S. Campbell, Hui Shen, Stephen B. Baylin, Michael J. Topper, Jean-Pierre J. Issa, David I. Quinn, Noah M. Hahn, Jozef Madzo, Woonbok Chung, Peter W. Nichols, Pooja Ghatalia, Matthew R. Zibelman, Daniel M. Geynisman, Rutika Kokate, Candice L. Schwebel, R. Katherine Alpaugh, Mahvish Tafseer, Ryan S. Burgos, Justin R. Kulchycki, Toshinori Hinoue, Eric A. Ross, Zachary Madaj, Alexander W. Macfarlane, Galen Hostetter, H. Josh Jang
Supplementary Figure 6: Gene Set Enrichment Analysis reveals immune-related pathways discriminate PD and SD tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d50eef20be4c69f174db6fc5222ab1
https://doi.org/10.1158/1078-0432.22587048.v1
https://doi.org/10.1158/1078-0432.22587048.v1
Autor:
Elizabeth R. Plimack, Peter A. Jones, Kerry S. Campbell, Hui Shen, Stephen B. Baylin, Michael J. Topper, Jean-Pierre J. Issa, David I. Quinn, Noah M. Hahn, Jozef Madzo, Woonbok Chung, Peter W. Nichols, Pooja Ghatalia, Matthew R. Zibelman, Daniel M. Geynisman, Rutika Kokate, Candice L. Schwebel, R. Katherine Alpaugh, Mahvish Tafseer, Ryan S. Burgos, Justin R. Kulchycki, Toshinori Hinoue, Eric A. Ross, Zachary Madaj, Alexander W. Macfarlane, Galen Hostetter, H. Josh Jang
Supplementary Figure 1: Patient recruitment and sample collection overview.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64461bb7702b192c870dadeb4197d508
https://doi.org/10.1158/1078-0432.22587072
https://doi.org/10.1158/1078-0432.22587072
Autor:
Elizabeth R. Plimack, Peter A. Jones, Kerry S. Campbell, Hui Shen, Stephen B. Baylin, Michael J. Topper, Jean-Pierre J. Issa, David I. Quinn, Noah M. Hahn, Jozef Madzo, Woonbok Chung, Peter W. Nichols, Pooja Ghatalia, Matthew R. Zibelman, Daniel M. Geynisman, Rutika Kokate, Candice L. Schwebel, R. Katherine Alpaugh, Mahvish Tafseer, Ryan S. Burgos, Justin R. Kulchycki, Toshinori Hinoue, Eric A. Ross, Zachary Madaj, Alexander W. Macfarlane, Galen Hostetter, H. Josh Jang
Supplementary Figure 3: Copy number variation detected by SeSAMe from DNA methylation data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7ae8ea7b351a397ed53daff9bb7784
https://doi.org/10.1158/1078-0432.22587057
https://doi.org/10.1158/1078-0432.22587057
Autor:
Elizabeth R. Plimack, Peter A. Jones, Kerry S. Campbell, Hui Shen, Stephen B. Baylin, Michael J. Topper, Jean-Pierre J. Issa, David I. Quinn, Noah M. Hahn, Jozef Madzo, Woonbok Chung, Peter W. Nichols, Pooja Ghatalia, Matthew R. Zibelman, Daniel M. Geynisman, Rutika Kokate, Candice L. Schwebel, R. Katherine Alpaugh, Mahvish Tafseer, Ryan S. Burgos, Justin R. Kulchycki, Toshinori Hinoue, Eric A. Ross, Zachary Madaj, Alexander W. Macfarlane, Galen Hostetter, H. Josh Jang
Supplementary Figure 2: Modest treatment-induced DNA methylation changes in UC tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fb5d786eb556d1ff27e576b16c29e6
https://doi.org/10.1158/1078-0432.22587060.v1
https://doi.org/10.1158/1078-0432.22587060.v1
Autor:
Elizabeth R. Plimack, Peter A. Jones, Kerry S. Campbell, Hui Shen, Stephen B. Baylin, Michael J. Topper, Jean-Pierre J. Issa, David I. Quinn, Noah M. Hahn, Jozef Madzo, Woonbok Chung, Peter W. Nichols, Pooja Ghatalia, Matthew R. Zibelman, Daniel M. Geynisman, Rutika Kokate, Candice L. Schwebel, R. Katherine Alpaugh, Mahvish Tafseer, Ryan S. Burgos, Justin R. Kulchycki, Toshinori Hinoue, Eric A. Ross, Zachary Madaj, Alexander W. Macfarlane, Galen Hostetter, H. Josh Jang
Supplementary Figure 9: CD8 infiltration in tumor is associated with survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e278bd6243da9d2a70048ae22853211
https://doi.org/10.1158/1078-0432.22587039
https://doi.org/10.1158/1078-0432.22587039
Autor:
Elizabeth R. Plimack, Peter A. Jones, Kerry S. Campbell, Hui Shen, Stephen B. Baylin, Michael J. Topper, Jean-Pierre J. Issa, David I. Quinn, Noah M. Hahn, Jozef Madzo, Woonbok Chung, Peter W. Nichols, Pooja Ghatalia, Matthew R. Zibelman, Daniel M. Geynisman, Rutika Kokate, Candice L. Schwebel, R. Katherine Alpaugh, Mahvish Tafseer, Ryan S. Burgos, Justin R. Kulchycki, Toshinori Hinoue, Eric A. Ross, Zachary Madaj, Alexander W. Macfarlane, Galen Hostetter, H. Josh Jang
Supplementary TablesSupplementary Table 1: Patient and tumor sample informationSupplementary Table 2: Tumor mutation burdenSupplementary Table 3: Unfiltered whole exome sequencing mutation analysisSupplementary Table 4: Filtered whole exome sequencin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060df0332a16728b73018ccfae5db307
https://doi.org/10.1158/1078-0432.22587036.v1
https://doi.org/10.1158/1078-0432.22587036.v1