Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Justin R. Hughey"'
Autor:
Michael M. Puppolo, Justin R. Hughey, Bruce Weber, Traciann Dillon, David Storey, Elizabeth Cerkez, Susan Jansen-Varnum
Publikováno v:
AAPS Open, Vol 3, Iss 1, Pp 1-13 (2017)
Abstract Biorelevant dissolution is an indispensable tool utilized during formulation development and optimization for the prediction of in vivo bioavailability of pharmaceutical agents. Within that framework, membrane-permeation dissolution methodol
Externí odkaz:
https://doaj.org/article/fec40d8d9c684778aae65c8748c2e301
Publikováno v:
Formulating Poorly Water Soluble Drugs ISBN: 9783030887186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cb946d8a4232491d78c638573802e2f
https://doi.org/10.1007/978-3-030-88719-3_3
https://doi.org/10.1007/978-3-030-88719-3_3
Autor:
Bruce Weber, Traciann Dillon, Justin R. Hughey, David Storey, Michael M. Puppolo, Susan A. Jansen‐Varnum, Elizabeth B. Cerkez
Publikováno v:
AAPS Open, Vol 3, Iss 1, Pp 1-13 (2017)
Biorelevant dissolution is an indispensable tool utilized during formulation development and optimization for the prediction of in vivo bioavailability of pharmaceutical agents. Within that framework, membrane-permeation dissolution methodologies are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813f1f12bbdfed78f3d4203cd5231396
http://link.springer.com/article/10.1186/s41120-017-0019-4
http://link.springer.com/article/10.1186/s41120-017-0019-4
Publikováno v:
AAPS PharmSciTech. 18:2841-2853
The presented study describes the development of a membrane permeation non-sink dissolution method that can provide analysis of complete drug speciation and emulate the in vivo performance of poorly water-soluble Biopharmaceutical Classification Syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba96e4b70ea8d54913d85b37cd7bb0a
https://doi.org/10.1208/s12249-017-0783-4
https://doi.org/10.1208/s12249-017-0783-4
Autor:
Justin M. Keen, James W. McGinity, Justin R. Hughey, Vincent Jannin, Ryan C. Bennett, Connor J. Foley, Yvonne Rosiaux, Delphine Marchaud
Publikováno v:
International Journal of Pharmaceutics. 487:72-80
Interest in granulation processes using twin screw extrusion machines is rapidly growing. The primary objectives of this study were to develop a continuous granulation process for direct production of granules using this technique with glyceryl behen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6174d0a71595d6fb131e6e4e3e15853
https://doi.org/10.1016/j.ijpharm.2015.03.058
https://doi.org/10.1016/j.ijpharm.2015.03.058
Autor:
Justin R. Hughey
Publikováno v:
Poorly Soluble Drugs: Dissolution and Drug Release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3e7fc20394e83dc1187ee2e3a23dd17
https://doi.org/10.1201/9781315364537-13
https://doi.org/10.1201/9781315364537-13
Publikováno v:
Drug Development and Industrial Pharmacy. 41:1294-1301
While the use of amorphous solid dispersions to improve aqueous solubility is well documented, little consideration has traditionally been given to the finished dosage form. The objective of this study was to evaluate the dissolution performance of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504685025a2ae169c14b6cd0dd62d6ef
https://doi.org/10.3109/03639045.2014.947508
https://doi.org/10.3109/03639045.2014.947508
Publikováno v:
AAPS PharmSciTech. 19(5)
The formulation factors relevant to developing immediate and controlled release dosage forms containing poorly soluble drugs dispersed in amorphous systems are poorly understood. While the utility of amorphous solid dispersions is becoming apparent i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e8b8bf837f7733276bb0357fb78fcd
https://pubmed.ncbi.nlm.nih.gov/29192405
https://pubmed.ncbi.nlm.nih.gov/29192405
Publikováno v:
Formulating Poorly Water Soluble Drugs ISBN: 9783319426075
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d25cff1928f934d665507a8dfc612d47
https://doi.org/10.1007/978-3-319-42609-9_3
https://doi.org/10.1007/978-3-319-42609-9_3