Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Justin P. Roberts"'
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 131-131 (2024)
OBJECTIVES/GOALS: The CDC estimates that Influenza infections account for an average of 420,000 hospitalizations and 34,700 deaths in the U.S. each year. This project explores the underlying mechanisms of the infectious process of Influenza A in huma
Externí odkaz:
https://doaj.org/article/494e4aa1702544f2b1f826df853fce56
Autor:
Henry C Chung, Don R Keiller, Patrick M Swain, Shaun L Chapman, Justin D Roberts, Dan A Gordon
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0288996 (2023)
Cardiorespiratory fitness is a key component of health-related fitness. It is a necessary focus of improvement, especially for those that have poor fitness and are classed as untrained. However, much research has shown individuals respond differentia
Externí odkaz:
https://doaj.org/article/57aca595478f49a3ab61e7e230f8e3cc
Autor:
Allison M Porman, Justin T Roberts, Emily D Duncan, Madeline L Chrupcala, Ariel A Levine, Michelle A Kennedy, Michelle M Williams, Jennifer K Richer, Aaron M Johnson
Publikováno v:
PLoS Biology, Vol 20, Iss 11, p e3001885 (2022)
N6-methyladenosine (m6A) modification of RNA regulates normal and cancer biology, but knowledge of its function on long noncoding RNAs (lncRNAs) remains limited. Here, we reveal that m6A regulates the breast cancer-associated human lncRNA HOTAIR. Map
Externí odkaz:
https://doaj.org/article/64ddea15eef444408f11c50b7522ba53
Autor:
Grant T. Daly, Viktor M. Pastukh, Yong B. Tan, C. Michael Francis, C. Zack Aggen, S. Chris Groark, Carson Edwards, Madhuri S. Mulekar, Mohammad Hamo, Jon D. Simmons, Matthew E. Kutcher, Emily M. Hartsell, Darrell L. Dinwiddie, Zachary M. Turpin, Hank W. Bass, Justin T. Roberts, Mark N. Gillespie, Raymond J. Langley
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 10, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/4c19c86930224c669d880a5a57da76ec
Autor:
Matthew J. W. Furber, Gregory R. Young, Giles S. Holt, Simone Pyle, Glen Davison, Michael G. Roberts, Justin D. Roberts, Glyn Howatson, Darren L. Smith
Publikováno v:
mSystems, Vol 7, Iss 3 (2022)
ABSTRACT Dietary manipulation with high-protein or high-carbohydrate content are frequently employed during elite athletic training, aiming to enhance athletic performance. Such interventions are likely to impact upon gut microbial content. This stud
Externí odkaz:
https://doaj.org/article/396cfa398db64f5b8ac10ae32fc062f9
Autor:
Scott T. Chiesa, Marietta Charakida, Georgios Georgiopoulos, Justin D. Roberts, Simon J. Stafford, Chloe Park, Juha Mykkänen, Mika Kähönen, Terho Lehtimäki, Mika Ala‐Korpela, Olli Raitakari, Milla Pietiäinen, Pirkko Pussinen, Vivek Muthurangu, Alun D. Hughes, Naveed Sattar, Nicholas J. Timpson, John E. Deanfield
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 4 (2022)
Background Low‐grade inflammation in the young may contribute to the early development of cardiovascular disease. We assessed whether circulating levels of glycoprotein acetyls (GlycA) were better able to predict the development of adverse cardiova
Externí odkaz:
https://doaj.org/article/0aac8b599987442fa69aba6e405d172e
Autor:
Natalia B. Fernández, Sofía M. Sosa, Justin T. Roberts, María S. Recouvreux, Luciana Rocha-Viegas, Jessica L. Christenson, Nicole S. Spoelstra, Facundo L. Couto, Ana R. Raimondi, Jennifer K. Richer, Natalia Rubinstein
Publikováno v:
Cells, Vol 12, Iss 3, p 444 (2023)
Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype for which no effective targeted therapies are available. Growing evidence suggests that chemotherapy-resistant cancer cells with stem-like properties (CSC) may repopulate the
Externí odkaz:
https://doaj.org/article/82ee5a10864e493fb5f423a04c49e88e
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0249501 (2021)
The aim of this systematic review and meta-analysis was to identify a list of common, candidate genes associated with the three components of fitness, specifically cardiovascular fitness, muscular strength, and anaerobic power, and how these genes ar
Externí odkaz:
https://doaj.org/article/8c5e2073d0234c78b9b54a66ddb5955a
Autor:
Alexander B. Coley, Ashlyn N. Stahly, Mohan V. Kasukurthi, Addison A. Barchie, Sam B. Hutcheson, Dominika Houserova, Yulong Huang, Brianna C. Watters, Valeria M. King, Meghan A. Dean, Justin T. Roberts, Jeffrey D. DeMeis, Krisha V. Amin, Cameron H. McInnis, Noel L. Godang, Ryan M. Wright, David F. Haider, Neha B. Piracha, Cana L. Brown, Zohaib M. Ijaz, Shengyu Li, Yaguang Xi, Oliver G. McDonald, Jingshan Huang, Glen M. Borchert
Publikováno v:
Cells, Vol 11, Iss 8, p 1302 (2022)
We have identified 38 specifically excised, differentially expressed snoRNA fragments (sdRNAs) in TCGA prostate cancer (PCa) patient samples as compared to normal prostate controls. SnoRNA-derived fragments sdRNA-D19b and -A24 emerged among the most
Externí odkaz:
https://doaj.org/article/9182b61431ac4798a4faa32a687b4a27
Autor:
Jay H. Kalin, Muzhou Wu, Andrea V. Gomez, Yun Song, Jayanta Das, Dawn Hayward, Nkosi Adejola, Mingxuan Wu, Izabela Panova, Hye Jin Chung, Edward Kim, Holly J. Roberts, Justin M. Roberts, Polina Prusevich, Jeliazko R. Jeliazkov, Shourya S. Roy Burman, Louise Fairall, Charles Milano, Abdulkerim Eroglu, Charlotte M. Proby, Albena T. Dinkova-Kostova, Wayne W. Hancock, Jeffrey J. Gray, James E. Bradner, Sergio Valente, Antonello Mai, Nicole M. Anders, Michelle A. Rudek, Yong Hu, Byungwoo Ryu, John W. R. Schwabe, Andrea Mattevi, Rhoda M. Alani, Philip A. Cole
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Alteration of the epigenetic landscape has been implicated in several disease processes, where targeting histone modifiers may have therapeutic applications. Here the authors report a bifunctional small molecule inhibitor that simultaneously targets
Externí odkaz:
https://doaj.org/article/879832a39de54eeeb00cc6a12113408e