Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Justin P Rubio"'
Autor:
Paul A Wilson, Sara Santos Franco, Liu He, Nicholas W Galwey, Jackie Meakin, Rebecca McIntyre, Simon M McHugh, Michael A Nolan, Sarah L Spain, Thaddeus Carlson, Mercedes Lobera, Justin P Rubio, Bill Davis, Linda C McCarthy
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258316 (2021)
RORγt is an isoform of RORC, preferentially expressed in Th17 cells, that functions as a critical regulator of type 3 immunity. As murine Th17-driven inflammatory disease models were greatly diminished in RORC knock-out mice, this receptor was prior
Externí odkaz:
https://doaj.org/article/9579a389fd9d4fd68176d966c4cda4dc
Autor:
Yongfeng Chen, Wei Zhen, Tony Guo, Yonggang Zhao, Ailian Liu, Justin P Rubio, David Krull, Jill C Richardson, Hongtao Lu, Ryan Wang
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189380 (2017)
Agents promoting oligodendrocyte precursor cell differentiation have the potential to restore halted and/or delayed remyelination in patients with multiple sclerosis. However, few therapeutic targets have been identified. The objective of this study
Externí odkaz:
https://doaj.org/article/90cda7d5da394f42a77356dbbee8e3a5
Autor:
Judith Field, Sharon R Browning, Laura J Johnson, Patrick Danoy, Michael D Varney, Brian D Tait, Kaushal S Gandhi, Jac C Charlesworth, Robert N Heard, Australia and New Zealand Multiple Sclerosis Genetics Consortium, Graeme J Stewart, Trevor J Kilpatrick, Simon J Foote, Melanie Bahlo, Helmut Butzkueven, James Wiley, David R Booth, Bruce V Taylor, Matthew A Brown, Justin P Rubio, Jim Stankovich
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13454 (2010)
We conducted an association study across the human leukocyte antigen (HLA) complex to identify loci associated with multiple sclerosis (MS). Comparing 1927 SNPs in 1618 MS cases and 3413 controls of European ancestry, we identified seven SNPs that we
Externí odkaz:
https://doaj.org/article/666c12ee17314e0d830ff51e46de6064
Autor:
Cathy J Jensen, Jim Stankovich, Anneke Van der Walt, Melanie Bahlo, Bruce V Taylor, Ingrid A F van der Mei, Simon J Foote, Trevor J Kilpatrick, Laura J Johnson, Ella Wilkins, Judith Field, Patrick Danoy, Matthew A Brown, Australian and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Justin P Rubio, Helmut Butzkueven
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10003 (2010)
Recent association studies in multiple sclerosis (MS) have identified and replicated several single nucleotide polymorphism (SNP) susceptibility loci including CLEC16A, IL2RA, IL7R, RPL5, CD58, CD40 and chromosome 12q13-14 in addition to the well est
Externí odkaz:
https://doaj.org/article/13cb2becb1be45648188bdae2e91bbeb
Autor:
Seema Husain, Cagri Yildirim-Toruner, Justin P Rubio, Judith Field, Southern MS Genetics Consortium, Marvin Schwalb, Stuart Cook, Marcella Devoto, Emilia Vitale
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2653 (2008)
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system of unknown etiology with both genetic and environmental factors playing a role in susceptibility. To date, the HLA DR15/DQ6 haplotype within the major hist
Externí odkaz:
https://doaj.org/article/29284e3ed38c4bfcacc9da58ad36dced
Autor:
Justin P. Rubio, Matthew A. Brown, Sharon R. Browning, Bruce V. Taylor, Peter F. Hickey, Patrick Danoy, Jim Stankovich, Melanie Bahlo
As of June 2009, 361 genome-wide association studies (GWAS) had been referenced by the HuGE database. GWAS require DNA from many thousands of individuals, relying on suitable DNA collections. We recently performed a multiple sclerosis (MS) GWAS where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c273e0a6f6158c939a184cc6ddd221c
https://doi.org/10.1158/1055-9965.c.6515103.v1
https://doi.org/10.1158/1055-9965.c.6515103.v1
Autor:
Justin P. Rubio, Matthew A. Brown, Sharon R. Browning, Bruce V. Taylor, Peter F. Hickey, Patrick Danoy, Jim Stankovich, Melanie Bahlo
Supplementary Figures 1-5, Supplementary Tables 1-3, Full List of Authors and Affiliations from Saliva-Derived DNA Performs Well in Large-Scale, High-Density Single-Nucleotide Polymorphism Microarray Studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8581263ec7b7bd113e364a5653f4d17
https://doi.org/10.1158/1055-9965.22435788
https://doi.org/10.1158/1055-9965.22435788
Autor:
Allan Motyer, Stacey Jackson, Bicheng Yang, Ivon Harliwong, Wei Tian, Wingin Shiu, Yunchang Shao, Bo Wang, Catriona McLean, Michael Barnett, Trevor J. Kilpatrick, Stephen Leslie, Justin P. Rubio
Neuroinflammation has been linked to DNA damage in multiple sclerosis (MS), but its impact on neural cell genomes at nucleotide resolution is unknown. To address this question, we performed single nucleus whole genome sequencing to determine the land
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d39c6969f1a8b9547f9b3957ad6dc091
https://doi.org/10.1101/2022.04.30.490132
https://doi.org/10.1101/2022.04.30.490132
Autor:
Simon M. McHugh, Bill Davis, Liu He, Jackie Meakin, Paul A. Wilson, Sara Santos Franco, Thaddeus J. Carlson, Mercedes Lobera, Linda McCarthy, Justin P. Rubio, Sarah L. Spain, Rebecca E. McIntyre, Michael A. Nolan, Nicholas Galwey
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258316 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 10 (2021)
RORγt is an isoform of RORC, preferentially expressed in Th17 cells, that functions as a critical regulator of type 3 immunity. As murine Th17-driven inflammatory disease models were greatly diminished in RORC knock-out mice, this receptor was prior
Autor:
George D. Mellick, Danuta Z. Loesch, Malcolm K. Horne, Elsdon Storey, Justin P. Rubio, David J. Francis, Flora Tassone, Minh Bui
Publikováno v:
Movement Disorders. 33:1178-1181
Background and Objective There is convincing evidence that small CGG expansion (41-54 repeats): FMR1 "gray zone" alleles (GZ) contribute to the risk of parkinsonism in males, but there is insufficient corresponding data in females. This study intends