Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Justin N. Siemian"'
Autor:
Justin N. Siemian, Miguel A. Arenivar, Sarah Sarsfield, Cara B. Borja, Charity N. Russell, Yeka Aponte
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109615- (2021)
Summary: Assigning behavioral roles to genetically defined neurons within the lateral hypothalamus (LH) is an ongoing challenge. We demonstrate that a subpopulation of LH GABAergic neurons expressing leptin receptors (LHLEPR) specifically drives appe
Externí odkaz:
https://doaj.org/article/ed31d5cc750c4e76b0179c6a2391d119
Autor:
Jennifer A. Martin, Craig T. Werner, Swarup Mitra, Ping Zhong, Zi-Jun Wang, Pedro H. Gobira, Andrew. F. Stewart, Jay Zhang, Kyra Erias, Justin N. Siemian, Devin Hagarty, Lauren E. Mueller, Rachael L. Neve, Jun-Xu Li, Ramesh Chandra, Karen C. Dietz, Mary Kay Lobo, Amy M. Gancarz, Zhen Yan, David M. Dietz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The underlying transcriptional and cellular events mediating the reduction of dendritic spines on medium spiny neurons of the nucleus accumbens (NAc) remains unknown. Here, authors demonstrate that heroin self-administration negatively regulates the
Externí odkaz:
https://doaj.org/article/fd3986183cd145e696e221b400cee251
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract A pivotal role of the lateral hypothalamus (LH) in regulating appetitive and reward-related behaviors has been evident for decades. However, the contributions of LH circuits to other survival behaviors have been less explored. Here we examin
Externí odkaz:
https://doaj.org/article/d0a594f60e23400196e7204bf33e03e1
Autor:
Justin N Siemian, Miguel A Arenivar, Sarah Sarsfield, Cara B Borja, Lydia J Erbaugh, Andrew L Eagle, Alfred J Robison, Gina Leinninger, Yeka Aponte
Publikováno v:
eLife, Vol 10 (2021)
Understanding how neuronal circuits control nociceptive processing will advance the search for novel analgesics. We use functional imaging to demonstrate that lateral hypothalamic parvalbumin-positive (LHPV) glutamatergic neurons respond to acute the
Externí odkaz:
https://doaj.org/article/d987831fe0d3440cb4cb1f9e6d3a0ac8
Autor:
Cara B. Borja, Justin N. Siemian, Sarah Sarsfield, Miguel A. Arenivar, Yeka Aponte, Charity N. Russell
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109615-(2021)
Cell reports
Cell reports
SUMMARY Assigning behavioral roles to genetically defined neurons within the lateral hypothalamus (LH) is an ongoing challenge. We demonstrate that a subpopulation of LH GABAergic neurons expressing leptin receptors (LHLEPR) specifically drives appet
Publikováno v:
Curr Biol
While energy balance is critical to survival, many factors influence food intake beyond caloric need or “hunger.” Despite this, some neurons that drive feeding in mice are routinely referred to as “hunger neurons,” whereas others are not. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d07265ff5ee229008f0fc58e7b08450
https://europepmc.org/articles/PMC8440483/
https://europepmc.org/articles/PMC8440483/
Autor:
Gina M. Leinninger, Yeka Aponte, Miguel A. Arenivar, Justin N. Siemian, Cara B. Borja, Lydia J Erbaugh, Andrew L. Eagle, Alfred J. Robison, Sarah Sarsfield
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Understanding how neuronal circuits control nociceptive processing will advance the search for novel analgesics. We use functional imaging to demonstrate that lateral hypothalamic parvalbumin-positive (LHPV) glutamatergic neurons respond to acute the
Autor:
Zi-Jun Wang, Amy M. Gancarz, Pedro H. Gobira, Ping Zhong, Kyra Erias, Zhen Yan, Swarup Mitra, Jennifer A. Martin, Craig T. Werner, Justin N. Siemian, Lauren E. Mueller, Andrew F. Stewart, Rachael L. Neve, Jay Zhang, Ramesh Chandra, David M. Dietz, Mary Kay Lobo, Devin Hagarty, Jun-Xu Li, Karen C. Dietz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Persistent transcriptional and morphological events in the nucleus accumbens (NAc) and other brain reward regions contribute to the long-lasting behavioral adaptations that characterize drug addiction. Opiate exposure reduces the density of dendritic
Publikováno v:
Behav Pharmacol
Pharmacotherapies for fibromyalgia treatment are lacking. This study examined the antinociceptive and antidepressant-like effects of imidazoline I2 receptor (I2R) agonists in a reserpine-induced model of fibromyalgia in rats. Rats were treated for 3
Publikováno v:
Behav Pharmacol
Previous preclinical research suggests that L-methamphetamine (L -MA) has potential therapeutic utility to treat psychostimulant abuse. This study examined potential abuse-related and adverse physiological effects of D -MA and L -MA alone and in comb