Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Justin M. Farook"'
Publikováno v:
The Journal of Neuroscience. 33:17398-17403
Increased cranial pressure due to development of edema contributes significantly to the pathology of traumatic brain injury (TBI). Induction of an astrocytic water channel protein, Aquaporin 4 (AQP4), is known to predominantly contribute to cytotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d194453dcc5c0bb9ad7faa6ad19fd65
https://doi.org/10.1523/jneurosci.2756-13.2013
https://doi.org/10.1523/jneurosci.2756-13.2013
Publikováno v:
Physiology & Behavior. 97:503-506
Lobeline is a partial nicotinic agonist and is currently being investigated as a therapeutic drug for several addictive disorders particularly for smoking cessation. The present study evaluated the effects of repeated (continuous and recurring) admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e409e38860b6b740a81e69fc1fc98e79
https://doi.org/10.1016/j.physbeh.2009.02.031
https://doi.org/10.1016/j.physbeh.2009.02.031
Autor:
Nilkantha Sen, Tanusree Sen, Justin M. Farook, Risheng Xu, Thomas W. Sedlak, Jay M. Baraban, Solomon H. Snyder, Anthony V. Serritella
Publikováno v:
Neuron. 79(1)
SummaryCocaine’s behavioral-stimulant effects derive from potentiation of synaptic signaling by dopamine and serotonin leading to transcriptional alterations in postsynaptic cells. We report that a signaling cascade involving nitric oxide (NO) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82bf1ae125cb14a9139be30e4a2f51c
Autor:
Kristen Wellmann, Dennis T. Rogers, Josh Ring, John M. Littleton, Peter A. Crooks, Megan Carter, Robert C. Holley, Ben Lewis, Justin M. Farook, Susan Barron
Publikováno v:
Scopus-Elsevier
Relapse and neurodegeneration are two of the major therapeutic targets in alcoholism. Fortuitously, the roles of glutamate/NMDA receptors (NMDARs) in withdrawal, conditioning and neurotoxicity mean that NMDAR inhibitors are potentially valuable for b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c0fea03ecb2066b0da30e00b91dc28
https://pubmed.ncbi.nlm.nih.gov/22574674
https://pubmed.ncbi.nlm.nih.gov/22574674
Publikováno v:
Neuroscience Letters.
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpoli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612740039d0e97c0939b076c893a487b
https://doi.org/10.1016/j.neulet.2010.11.045
https://doi.org/10.1016/j.neulet.2010.11.045
Autor:
Alexandra Kowalski, Justin M. Farook, Tracy D. Stepanyan, John M. Littleton, Susan Barron, Eva Kaplan
Publikováno v:
Alcoholism, clinical and experimental research. 32(12)
Background: The ethanol withdrawal (EWD) syndrome is typically treated using benzodiazepines such as diazepam. However there is concern that benzodiazepines may not prevent neurotoxicity associated with EWD. Antagonists of glutamate/N-Methyl-D-Aspart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d210d22078d134a4e6dc163e945b91f9
https://pubmed.ncbi.nlm.nih.gov/18828800
https://pubmed.ncbi.nlm.nih.gov/18828800
Publikováno v:
Physiologybehavior. 96(1)
Stress increases the risk for alcohol abuse and relapse behaviors. However, there are hardly any medications to counteract stress-induced alcoholism and relapse behaviors. The present study examined the effects of topiramate (intraperitoneal injectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9fc03684538a69fd34e1b5e0bdd626
https://pubmed.ncbi.nlm.nih.gov/18786555
https://pubmed.ncbi.nlm.nih.gov/18786555
In the present study, we examined the effects of acamprosate for its ability to reduce handling induced convulsions (HICs) during alcohol withdrawal. Diazepam was used as a positive control. Swiss Webster male mice received three daily IP injections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1033244776f06e556a722e871c1af2b
https://europepmc.org/articles/PMC2561203/
https://europepmc.org/articles/PMC2561203/
Autor:
Sung Mok Kim, Huang Hui, Mikio Nakazawa, Komei Tanaka, Wang Canjun, Maria Culici, Shelley B. Hooks, Justin G. Gaddis, Seo Young Yoon, R. Morelli, Elliot Yung, Ben Lewis, Song Li-hua, Kazuki Okamura, Jonathan Weinberg, Xu Bingfa, Wei Wei, Jae Hoon Cheong, Joel Yarmush, Takeshi Adachi, Roberto Lo Scalzo, Jillian H. Hurst, Fan Qinglin, Justin M. Farook, Yong-Chul Kim, Alessandra Spallino, Sidhartha D. Ray, Masaomi Chinushi, Yoshifusa Aizawa, Chul-Seung Park, Satoru Hirono, Susan Barron, Ike Campomayor dela Peña, Aldo Bertelli, Masahiro Ito, John M. Littleton, Pier Carlo Braga, Wataru Mitsuma, Mario Falchi, Geum Seon Lee, Jong Hoon Ryu, Monica Dal Sasso, Joseph SchianodiCola, Makoto Kodama
Publikováno v:
Pharmacology. 83:387-388
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfad6a002a61a769297750bf7caa5731
https://doi.org/10.1159/000224625
https://doi.org/10.1159/000224625
Autor:
Nilkantha Sen, Amany Tawfik, Sylvia B. Smith, Justin M. Farook, Shanu Markand, Krishnan M. Dhandapani, Darrell W. Brann, Jessica Shields, Tanusree Sen
Publikováno v:
Cell Death & Disease
Neuronal cell death contributes significantly to the pathology of traumatic brain injury (TBI) irrespective of the mode or severity of the injury. Activation of a pro-survival protein, Akt, is known to be regulated by an E3 ligase TRAF6 through a pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b49e3efb37d6a1c2204a57704b0228
https://doi.org/10.1038/cddis.2013.336
https://doi.org/10.1038/cddis.2013.336