Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Justin L. Spinner"'
Autor:
Justin L Spinner, Keun Seok Seo, Jason L O'Loughlin, Jennifer A Cundiff, Scott A Minnich, Gregory A Bohach, Scott D Kobayashi
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9279 (2010)
BackgroundThe human innate immune system relies on the coordinated activity of macrophages and polymorphonuclear leukocytes (neutrophils or PMNs) for defense against bacterial pathogens. Yersinia spp. subvert the innate immune response to cause disea
Externí odkaz:
https://doaj.org/article/3f5147da69a249e9a95227c3368a268c
Autor:
Scott D. Kobayashi, Jeffrey G. Shannon, Aaron M. Hasenkrug, B. Joseph Hinnebusch, Justin L. Spinner
Publikováno v:
Microbes and Infection. 18:21-29
Polymorphonuclear leukocytes, in addition to their direct bactericidal activities, produce cytokines involved in the activation and regulation of the innate and adaptive immune response to infection. In this study we evaluated the cytokine response o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acc45e6dabf76ec8a76c6a9060ab3e1
https://doi.org/10.1016/j.micinf.2015.08.015
https://doi.org/10.1016/j.micinf.2015.08.015
Autor:
Jeffrey G. Shannon, Vinod Nair, Justin L. Spinner, Olivia Steele-Mortimer, B. Joseph Hinnebusch, Tregei Starr, Seth Winfree
Publikováno v:
Journal of Leukocyte Biology. 95:389-398
Yersinia pestis, the bacterial agent of plague, is transmitted by fleas. The bite of an infected flea deposits Y. pestis into the dermis and triggers recruitment of innate immune cells, including phagocytic PMNs. Y. pestis can subvert this PMN respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bdfc58fc632c09a3cb1b7f85231a2c
https://doi.org/10.1189/jlb.1112551
https://doi.org/10.1189/jlb.1112551
Publikováno v:
Infection and Immunity. 81:4041-4052
Yersinia pestis carries homologues of the toxin complex (Tc) family proteins, which were first identified in other Gram-negative bacteria as having potent insecticidal activity. The Y. pestis Tc proteins are neither toxic to fleas nor essential for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01196845e18fed7cd5366174ae7a8dcf
https://doi.org/10.1128/iai.00648-13
https://doi.org/10.1128/iai.00648-13
Autor:
Martin Plante, David J. Burkhart, Jay T. Evans, Justin L. Spinner, Yvonne M. Yorgensen, Hardeep S. Oberoi, Danielle S. Poirier
Influenza is a vaccine-preventable contagious respiratory illness caused by influenza (flu) viruses which can lead to hospitalization and sometimes even death. Current flu vaccines delivered intramuscularly (IM) or intradermally (ID) are less effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f444563e467cdd7acb3e5cf3437b13
https://europepmc.org/articles/PMC4609623/
https://europepmc.org/articles/PMC4609623/
Publikováno v:
Advances in experimental medicine and biology. 954
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e31e5d854f1608e02cd6b1e25b765dd6
https://pubmed.ncbi.nlm.nih.gov/22782759
https://pubmed.ncbi.nlm.nih.gov/22782759
Publikováno v:
Advances in Yersinia Research ISBN: 9781461435600
Yersinia pestis, the bacterial agent of plague, is transmitted to a mammalian host through the bite of an infected flea. After deposition into the dermis, Y. pestis must subvert or prevent an effective innate immune response, including killing by pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b631425c0900fb7662af43399b711c96
https://doi.org/10.1007/978-1-4614-3561-7_20
https://doi.org/10.1007/978-1-4614-3561-7_20
Autor:
Jennifer A. Cundiff, Scott A. Minnich, Scott D. Kobayashi, Justin L. Spinner, Gregory A. Bohach, Keun Seok Seo, Jason L. O'Loughlin
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9279 (2010)
PLoS ONE
PLoS ONE
BackgroundThe human innate immune system relies on the coordinated activity of macrophages and polymorphonuclear leukocytes (neutrophils or PMNs) for defense against bacterial pathogens. Yersinia spp. subvert the innate immune response to cause disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8980921f02aec53ca99db6df64858a
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20174624/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20174624/?tool=EBI
Human polymorphonuclear leukocytes (PMNs, or neutrophils) are the most abundant innate immune cell and kill most invading bacteria through combined activities of reactive oxygen species (ROS) and antimicrobial granule constituents. Pathogens such asY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c13fdb1de72ee2e976ac0bbb77b895
https://europepmc.org/articles/PMC2812203/
https://europepmc.org/articles/PMC2812203/
Publikováno v:
Infection and immunity. 76(8)
Human polymorphonuclear leukocytes (PMNs, or neutrophils) are the primary innate host defense against invading bacterial pathogens. Neutrophils are rapidly recruited to sites of infection and ingest microorganisms through a process known as phagocyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9adb1e5a4c8d3e541d7e57845053a843
https://pubmed.ncbi.nlm.nih.gov/18490459
https://pubmed.ncbi.nlm.nih.gov/18490459