Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Justin L. Mott"'
Autor:
Prakash Kumar Sahoo, Chandan Krishnamoorthy, Jennifer R. Wood, Corrine Hanson, Ann Anderson-Berry, Justin L. Mott, Sathish Kumar Natarajan
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Maternal obesity increases the risk of childhood obesity and programs the offspring to develop metabolic syndrome later in their life. Palmitate is the predominant saturated free fatty acid (FFA) that is transported across the placenta to th
Externí odkaz:
https://doaj.org/article/5e1116ec305248fb8409170fac7a6dda
Autor:
Sathish Kumar Natarajan, Taylor Bruett, Philma Glora Muthuraj, Prakash K Sahoo, Jillian Power, Justin L Mott, Corrine Hanson, Ann Anderson-Berry
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249907 (2021)
IntroductionObesity during pregnancy increases the risk for maternal complications like gestational diabetes, preeclampsia, and maternal inflammation. Maternal obesity also increases the risk of childhood obesity, intrauterine growth restriction (IUG
Externí odkaz:
https://doaj.org/article/659586cf7d864a53a30b67e57c40c94e
Autor:
Sathish Kumar Natarajan, Bailey A. Stringham, Ashley M. Mohr, Cody J. Wehrkamp, Sizhao Lu, Mary Anne Phillippi, Dee Harrison-Findik, Justin L. Mott
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 5, Pp 866-875 (2017)
Nonalcoholic steatohepatitis (NASH) patients have elevated plasma saturated free fatty acid levels. These toxic fatty acids can induce liver cell death and our recent results demonstrated that the biliary epithelium may be susceptible to lipotoxicity
Externí odkaz:
https://doaj.org/article/a166e127fc9644ea9193a86b5553ff68
Autor:
Cody J. Wehrkamp, Andrew M. Oleksijew, Adrian P. Mansini, Sergio A. Gradilone, Ashley M. Mohr, Justin L. Mott
Cholangiocarcinoma is an aggressive solid tumor formed in the bile duct epithelium. Often this tumor obstructs bile flow, known as cholestasis. Normal cholangiocytes detect bile flow in the ductal lumen with an extension of the apical membrane called
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dde0fffb309059dbbd141b5431f6826
https://doi.org/10.1101/2023.03.01.530694
https://doi.org/10.1101/2023.03.01.530694
Publikováno v:
Biomolecules, Vol 5, Iss 4, Pp 3309-3338 (2015)
Alcohol consumption and its abuse is a major health problem resulting in significant healthcare cost in the United States. Chronic alcoholism results in damage to most of the vital organs in the human body. Among the alcohol-induced injuries, alcohol
Externí odkaz:
https://doaj.org/article/672b48719d7848ceb5dfcb3b0156a094
Publikováno v:
Clinical anatomy (New York, N.Y.). 35(7)
In this report, the authors examine the integration of teaching anatomical science with clinical implications in minimally invasive surgery. The authors hypothesized that implementation of integrated laparoscopic simulation during undergraduate medic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687b8d79dd73fb2fab8b81c8786f0bfd
https://pubmed.ncbi.nlm.nih.gov/35527395
https://pubmed.ncbi.nlm.nih.gov/35527395
Autor:
Sizhao Lu, Sathish Kumar Natarajan, Justin L Mott, Kusum K Kharbanda, Duygu Dee Harrison-Findik
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147474 (2016)
Changes in lipid metabolism and iron content are observed in the livers of patients with fatty liver disease. The expression of hepcidin, an iron-regulatory and acute phase protein synthesized by the liver, is also modulated. The potential interactio
Externí odkaz:
https://doaj.org/article/d93282b16515494b9ec1bfc7496e5819
Autor:
Andrew J. Phillips, Marissa B. Lobl, Yamnah A. Hafeji, Hannah R. Safranek, Ashley M. Mohr, Justin L. Mott
Publikováno v:
J Cell Biochem
Recent advances in targeted treatment for cholangiocarcinoma have focused on fibroblast growth factor (FGF) signaling. There are four receptor tyrosine kinases that respond to FGFs, and posttranslational processing has been demonstrated for each FGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dc9160f0e8b58e5d21d20e049cdff8
https://europepmc.org/articles/PMC8940645/
https://europepmc.org/articles/PMC8940645/
Autor:
Sophie C. Cazanave, Justin L. Mott, Nafisa A. Elmi, Steven F. Bronk, Howard C. Masuoka, Michael R. Charlton, Gregory J. Gores
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 8, Pp 1517-1525 (2011)
Saturated free fatty acids (FFA) induce hepatocyte lipoapoptosis, a key mediator of liver injury in nonalcoholic fatty liver disease (NAFLD). Lipoapoptosis involves the upregulation of the BH3-only protein PUMA, a potent pro-apoptotic protein. Given
Externí odkaz:
https://doaj.org/article/0c0d32d539874971b07358a5405ca195
Autor:
Cody J Wehrkamp, Ashley R Gutwein, Sathish Kumar Natarajan, Mary Anne Phillippi, Justin L Mott
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90238 (2014)
Cholangiocarcinoma cells are dependent on antiapoptotic signaling for survival and resistance to death stimuli. Recent mechanistic studies have revealed that increased cellular expression of the E3 ubiquitin-protein ligase X-linked inhibitor of apopt
Externí odkaz:
https://doaj.org/article/14c58f1d80a040a1b2d875764bd96b58