Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Justin L. Luebke"'
Autor:
Hui Peng, Jiangchuan Shen, Katherine A. Edmonds, Justin L. Luebke, Anne K. Hickey, Lauren D. Palmer, Feng-Ming James Chang, Kevin A. Bruce, Thomas E. Kehl-Fie, Eric P. Skaar, David P. Giedroc
Publikováno v:
mSphere, Vol 2, Iss 3 (2017)
ABSTRACT Staphylococcus aureus is a commensal human pathogen and a major cause of nosocomial infections. As gaseous signaling molecules, endogenous hydrogen sulfide (H2S) and nitric oxide (NO·) protect S. aureus from antibiotic stress synergisticall
Externí odkaz:
https://doaj.org/article/60c8556789154f8cabe92ef3914e72d7
Autor:
Katherine A. Edmonds, Mauro Bringas, Justin L. Luebke, Giovanni Gonzalez-Gutierrez, Daiana A. Capdevila, David P. Giedroc, Joseph N. Fakhoury, Yifan Zhang
Publikováno v:
Nucleic Acids Research
CstR is a persulfide-sensing member of the functionally diverse copper-sensitive operon repressor (CsoR) superfamily. While CstR regulates the bacterial response to hydrogen sulfide (H2S) and more oxidized reactive sulfur species (RSS) in Gram-positi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ef76267c71526941fa931fce31b477
https://doi.org/10.1101/2021.07.25.453692
https://doi.org/10.1101/2021.07.25.453692
Publikováno v:
Molecular Microbiology. 107:164-179
Bacterial signal transduction systems commonly use receiver (REC) domains, which regulate adaptive responses to the environment as a function of their phosphorylation state. REC domains control cell physiology through diverse mechanisms, many of whic
Publikováno v:
Biochemistry. 54:2385-2398
The cst operon of the major human pathogen Staphylococcus aureus (S. aureus) is under the transcriptional control of CsoR-like sulfurtransferase repressor (CstR). Expression of this operon is induced by hydrogen sulfide, and two components of the cst
Autor:
Kevin A. Bruce, Thomas E. Kehl-Fie, Eric P. Skaar, Lauren D. Palmer, Justin L. Luebke, Feng-Ming James Chang, Hui Peng, Katherine A. Edmonds, Jiangchuan Shen, Anne K. Hickey, David P. Giedroc
Publikováno v:
mSphere, Vol 2, Iss 3 (2017)
mSphere, Vol 2, Iss 3, p e00082-17 (2017)
mSphere
mSphere, Vol 2, Iss 3, p e00082-17 (2017)
mSphere
Hydrogen sulfide (H2S) is a toxic molecule and a recently described gasotransmitter in vertebrates whose function in bacteria is not well understood. In this work, we describe the transcriptomic response of the major human pathogen Staphylococcus aur
Autor:
David P. Giedroc, Justin L. Luebke
Publikováno v:
Biochemistry. 54(21)
Hosts employ myriad weapons to combat invading microorganisms as an integral feature of the host-bacterial pathogen interface. This interface is dominated by highly reactive small molecules that collectively induce oxidative stress. Successful pathog
Autor:
David P. Giedroc, Hui Peng, Justin L. Luebke, Eric P. Skaar, Kevin E. Bruce, Jiangchuan Shen, Thomas E. Kehl-Fie
Publikováno v:
Molecular microbiology. 94(6)
How cells regulate the bioavailability of utilizable sulfur while mitigating the effects of hydrogen sulfide toxicity is poorly understood. CstR [Copper-sensing operon repressor (CsoR)-like sulfurtransferase repressor] represses the expression of the
Autor:
Nicholi Vorsa, Lisa Kobs, Paul J. Limburg, Megan C. Leveranz, Ted Wilson, Emily J. Carrell, Ajay P. Singh, Erin F. Morcomb, Justin L. Luebke, Travis P. Schmidt
Publikováno v:
The FASEB Journal. 23
Publikováno v:
Metallomics. 5:335
Staphylococcus aureus CstR (CsoR-like sulfur transferase repressor) is a member of the CsoR family of transition metal sensing metalloregulatory proteins. Unlike CsoR, CstR does not form a stable complex with transition metals but instead reacts with