Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Justin L. Kandler"'
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 11, Pp n/a-n/a (2020)
Abstract Megacystis–microcolon–intestinal hypoperistalsis syndrome (MMIHS), or “visceral myopathy,” is a severe early onset disorder characterized by impaired muscle contractility in the bladder and intestines. Five genes are linked to MMIHS:
Externí odkaz:
https://doaj.org/article/33e704e0750e4d2cb1eeef7e76f45987
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144347 (2015)
Autophagy, an ancient homeostasis mechanism for macromolecule degradation, performs an important role in host defense by facilitating pathogen elimination. To counteract this host defense strategy, bacterial pathogens have evolved a variety of mechan
Externí odkaz:
https://doaj.org/article/23a716f693b748b7bcd77867991c89b1
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87688 (2014)
Neisseria gonorrhoeae is a strict human pathogen that causes the sexually transmitted infection termed gonorrhea. The gonococcus can survive extracellularly and intracellularly, but in both environments the bacteria must acquire iron from host protei
Externí odkaz:
https://doaj.org/article/9cc395f2e86a4950bc568926c514f31f
Autor:
Marcia M. Hobbs, James E. Anderson, Jacqueline T. Balthazar, Justin L. Kandler, Russell W. Carlson, Jhuma Ganguly, Afrin A. Begum, Joseph A. Duncan, Jessica T. Lin, P. Frederick Sparling, Ann E. Jerse, William M. Shafer
Publikováno v:
mBio, Vol 4, Iss 6 (2013)
ABSTRACT Phosphoethanolamine (PEA) on Neisseria gonorrhoeae lipid A influences gonococcal inflammatory signaling and susceptibility to innate host defenses in in vitro models. Here, we evaluated the role of PEA-decorated gonococcal lipid A in competi
Externí odkaz:
https://doaj.org/article/0d40931b05044f089514f13e40bf2e70
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 11, Pp n/a-n/a (2020)
Megacystis–microcolon–intestinal hypoperistalsis syndrome (MMIHS), or “visceral myopathy,” is a severe early onset disorder characterized by impaired muscle contractility in the bladder and intestines. Five genes are linked to MMIHS: primaril
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfaa3cc65a1edad45654822e52cb844
https://doi.org/10.1002/mgg3.1516
https://doi.org/10.1002/mgg3.1516
Autor:
Mary Kathryne Dickinson, Cynthia Nau Cornelissen, William M. Shafer, Devin R. Cash, Justin L. Kandler, Rosuany N. Vélez Acevedo
Publikováno v:
Molecular Microbiology. 102:137-151
Neisseria gonorrhoeae produces two transferrin binding proteins, TbpA and TbpB, which together enable efficient iron transport from human transferrin. We demonstrate that expression of the tbp genes is controlled by MisR, a response regulator in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd22fcb68e2d1dec0c0dff0f3d9aeab8
https://doi.org/10.1111/mmi.13450
https://doi.org/10.1111/mmi.13450
Autor:
Peter Cegielski, James E. Posey, Scott Burns, Alexandra Mercante, Justin L. Kandler, Beverly Metchock, Tracy Dalton, Matthew N. Ezewudo, Lauren S. Cowan
Resistance to the first-line anti-tuberculosis (TB) drug, isoniazid (INH), is widespread, and the mechanism of resistance is unknown in approximately 15% of INH-resistant (INH-R) strains. To improve molecular detection of INH-R TB, we used whole geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066282f3ab7d4d21ca8491ca5072b500
https://doi.org/10.1101/322750
https://doi.org/10.1101/322750
Autor:
William M. Shafer, Ann E. Jerse, Vijaya Dhulipala, Jacqueline T. Balthazar, Sandeep J. Joseph, Justin L. Kandler, Timothy D. Read
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:4230-4233
Phosphoethanolamine (PEA) decoration of lipid A produced by Neisseria gonorrhoeae has been linked to bacterial resistance to cationic antimicrobial peptides/proteins (CAMPs) and in vivo fitness during experimental infection. We now report that the lp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186899b78698310e09ba13f7eec7da05
https://doi.org/10.1128/aac.03108-14
https://doi.org/10.1128/aac.03108-14
Autor:
Artur Muszyński, Justin L. Kandler, Russell W. Carlson, Jacqueline T. Balthazar, Concerta L. Holley, Vijaya Dhulipala, Jennifer L. Reimche, William M. Shafer
Publikováno v:
Antimicrobial agents and chemotherapy. 60(8)
During infection, the sexually transmitted pathogen Neisseria gonorrhoeae (the gonococcus) encounters numerous host-derived antimicrobials, including cationic antimicrobial peptides (CAMPs) produced by epithelial and phagocytic cells. CAMPs have both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262591391d6141915233ff998db11afa
https://pubmed.ncbi.nlm.nih.gov/27216061
https://pubmed.ncbi.nlm.nih.gov/27216061
Autor:
Justin L, Kandler, Rosuany Vélez, Acevedo, Mary Kathryne, Dickinson, Devin R, Cash, William M, Shafer, Cynthia Nau, Cornelissen
Publikováno v:
Molecular microbiology. 102(1)
Neisseria gonorrhoeae produces two transferrin binding proteins, TbpA and TbpB, which together enable efficient iron transport from human transferrin. We demonstrate that expression of the tbp genes is controlled by MisR, a response regulator in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a85e897329459606884f01b6d5953ae4
https://pubmed.ncbi.nlm.nih.gov/27353397
https://pubmed.ncbi.nlm.nih.gov/27353397