Structure and fragmentation chemistry of the peptide radical cations of glycylphenylalanylglycine (GFG).

Autor: Yinan Li, Justin Kai-Chi Lau, Teun van Wieringen, Jonathan Martens, Giel Berden, Jos Oomens, Alan C Hopkinson, K W Michael Siu, Ivan K Chu

Publikováno v: PLoS ONE, Vol 19, Iss 8, p e0308164 (2024)

Herein, we explore the generation and characterization of the radical cations of glycylphenylalanylglycine, or [GFG]•+, formed via dissociative electron-transfer reaction from the tripeptide to copper(II) within a ternary complex. A comprehensive i

Externí odkaz: https://doaj.org/article/7193318e824240edb92993a91e1b1035

Structures and Dissociation Products of Ce/Peptide Complexes: Competition between Coordination and Charge Delocalization

Autor: Justin Kai-Chi Lau, K. W. Michael Siu, Alan C. Hopkinson, Yating Wang, Cheuk-Kuen Lai

Publikováno v: The Journal of Physical Chemistry B. 123:5229-5237

Structures of [Ce(GGG)]3+ and [Ce(GGG – H)]2+ have been investigated by DFT calculations. The two lowest-energy structures of the triply charged metal complex have the peptide in either the iminol ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ebbf5c8981daa1af7238db9a934cf0
https://doi.org/10.1021/acs.jpcb.9b03098

Structures of [GPGG + H - H2O](+) and [GPGG + H - H2O - NH=CH2](+) ions; evidence of rearrangement prior to dissociation

Autor: Alan C. Hopkinson, K. W. Michael Siu, Justin Kai-Chi Lau, Jonathan Martens, Ivan K. Chu, Jos Oomens, Cheuk-Kuen Lai, K.H. Brian Lam, Giel Berden

Publikováno v: International Journal of Mass Spectrometry, 442, 51-57
International Journal of Mass Spectrometry, 442, pp. 51-57

Infrared multiple photon dissociation (IRMPD) spectroscopy shows the [GPGG + H – H2O]+ ion to have an imidazolone structure. Collision-induced dissociation of this [b4]+ ion results in the loss of HN CH2 from the first residue; the IRMPD spectrum o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6dffbe18ff938d174dc72a6dbdb99b4
https://doi.org/10.1016/j.ijms.2019.04.006

Generation, Characterization, and Dissociation of Radical Cations Derived from Prolyl-glycyl-glycine

Autor: Victor Ryzhov, Jos Oomens, Francis Esuon, Alan C. Hopkinson, Giel Berden, K. W. Michael Siu, Justin Kai-Chi Lau

Publikováno v: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces and Biophysical, 125, 6121-6129
Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces and Biophysical, 125, 23, pp. 6121-6129

Radical cations of an aliphatic tripeptide prolyl-glycyl-glycine (PGG•+) and its sequence ions [a3 + H]•+ and [b2 - H]•+ have been generated by collision-induced dissociation of the [Cu(Phen)(PGG)]•2+ complex, where Phen = 1,10-phenanthroline

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bfc4ad1ee44e142801ace08393fa35
http://hdl.handle.net/2066/235638

Dissociation of [b5]+ ions containing an α-methyltryptophan and four alanine residues; losses of CO2 and the oxazolone ring

Autor: Alan C. Hopkinson, Justin Kai-Chi Lau, K. W. Michael Siu, Bai-Han Backen Wu

Publikováno v: International Journal of Mass Spectrometry. 429:28-38

The collision-induced dissociation spectra of isomeric [b 5 ] + ions consisting of an α-methyltryptophan and four alanine residues are very similar, indicating that there is a substantial amount of isomerization prior to fragmentation. The major dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0efe910d777819bbd65edb5bbe68ceaa
https://doi.org/10.1016/j.ijms.2017.04.013