Výsledky vyhledávání - "Justin K. Kirkham"

Akademický článek

Cyclin-Dependent Kinase CRK9, Required for Spliced Leader trans Splicing of Pre-mRNA in Trypanosomes, Functions in a Complex with a New L-Type Cyclin and a Kinetoplastid-Specific Protein.

Autor: Nitika Badjatia, Sung Hee Park, Daniela L Ambrósio, Justin K Kirkham, Arthur Günzl

Publikováno v: PLoS Pathogens, Vol 12, Iss 3, p e1005498 (2016)

In eukaryotes, cyclin-dependent kinases (CDKs) control the cell cycle and critical steps in gene expression. The lethal parasite Trypanosoma brucei, member of the phylogenetic order Kinetoplastida, possesses eleven CDKs which, due to high sequence di

Externí odkaz: https://doaj.org/article/64c28516282c440193788b3a94b39566

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Correction for Kirkham et al., 'Dynein Light Chain LC8 Is Required for RNA Polymerase I-Mediated Transcription in Trypanosoma brucei, Facilitating Assembly and Promoter Binding of Class I Transcription Factor A'

Autor: Tu N. Nguyen, Sung Hee Park, Arthur Günzl, Justin K. Kirkham, Ju Huck Lee

Dynein light chain LC8 is highly conserved among eukaryotes and has both dynein-dependent and dynein-independent functions. Interestingly, LC8 was identified as a subunit of the class I transcription factor A (CITFA), which is essential for transcrip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921becbb49b1a4872a5a5231e99d2e4e
https://europepmc.org/articles/PMC5452717/

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Cyclin-Dependent Kinase CRK9, Required for Spliced Leader trans Splicing of Pre-mRNA in Trypanosomes, Functions in a Complex with a New L-Type Cyclin and a Kinetoplastid-Specific Protein

Autor: Sung Hee Park, Justin K. Kirkham, Arthur Günzl, Nitika Badjatia, Daniela Luz Ambrósio

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 3, p e1005498 (2016)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0352d9d943ef9f45b3347b42bb3daf5

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Dynein Light Chain LC8 Is Required for RNA Polymerase I-Mediated Transcription in Trypanosoma brucei, Facilitating Assembly and Promoter Binding of Class I Transcription Factor A

Autor: Sung Hee Park, Arthur Günzl, Tu N. Nguyen, Ju Huck Lee, Justin K. Kirkham

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93200543c25d24ed45cb27285c54d370
https://europepmc.org/articles/PMC4702606/

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Mono-allelic VSG expression by RNA polymerase I in Trypanosoma brucei: expression site control from both ends?

Autor: Justin K. Kirkham, Sung Hee Park, Nitika Badjatia, Tu N. Nguyen, Arthur Günzl

Trypanosoma brucei is a vector borne, lethal protistan parasite of humans and livestock in sub-Saharan Africa. Antigenic variation of its cell surface coat enables the parasite to evade adaptive immune responses and to live freely in the blood of its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73581ed4653fa0d1feb956ac65e7dfa6
https://europepmc.org/articles/PMC4272636/

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A new strategy of RNA interference that targets heterologous sequences reveals CITFA1 as an essential component of class I transcription factor A in Trypanosoma brucei

Autor: Bao N. Nguyen, Tu N. Nguyen, Sung Hee Park, Justin K. Kirkham, Arthur Günzl

Publikováno v: Eukaryotic cell. 13(6)

Conditional gene silencing by RNA interference in Trypanosoma brucei can be inconclusive if knockdowns are inefficient or have off-target effects. To enable efficient, specific silencing of single-copy genes in mammalian-infective, bloodstream form t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da68acd9ac10991313eea903757fbd7
https://pubmed.ncbi.nlm.nih.gov/24728195

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Transcription by the multifunctional RNA polymerase I in Trypanosoma brucei functions independently of RPB7

Autor: Sung Hee Park, Justin K. Kirkham, Ju Huck Lee, Arthur Günzl, Tu N. Nguyen

Trypanosoma brucei has a multifunctional RNA polymerase (pol) I that transcribes ribosomal gene units (RRNA) and units encoding its major cell surface proteins variant surface glycoprotein (VSG) and procyclin. Previous analysis of tandem affinity-pur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2f415b570b87211fdfc64433f9015a
https://europepmc.org/articles/PMC3171583/

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Duration of oliguria and anuria as predictors of chronic renal-related sequelae in post-diarrheal hemolytic uremic syndrome

Autor: Robert S, Oakes, Justin K, Kirkham, Justin K, Kirkhamm, Raoul D, Nelson, Richard L, Siegler

Publikováno v: Pediatric nephrology (Berlin, Germany). 23(8)

Prior long-term retrospective studies have described renal sequelae in 25-50% of postdiarrheal hemolytic uremic syndrome (HUS) survivors, but the ability to predict the likelihood of chronic renal-related sequelae at the time of hospital discharge is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4671be9d013996c8fd2ea8712cdf2c6f
https://pubmed.ncbi.nlm.nih.gov/18465151

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