Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Justin K, Mikell"'
Publikováno v:
EJNMMI Physics, Vol 8, Iss 1, Pp 1-14 (2021)
Abstract Introduction Much progress has been made in implementing selective internal radiation therapy (SIRT) as a viable treatment option for hepatic malignancies. However, there is still much need for improved options for calculating the amount of
Externí odkaz:
https://doaj.org/article/6391d543694d4c82803cb7582d464174
Autor:
Justin K. Mikell, Ravi K. Kaza, Peter L. Roberson, Kelly C. Younge, Ravi N. Srinivasa, Bill S. Majdalany, Kyle C. Cuneo, Dawn Owen, Theresa Devasia, Matthew J. Schipper, Yuni K. Dewaraja
Publikováno v:
EJNMMI Physics, Vol 5, Iss 1, Pp 1-17 (2018)
Abstract Background The purpose was to validate 90Y PET gradient-based tumor segmentation in phantoms and to evaluate the impact of the segmentation method on reported tumor absorbed dose (AD) and biological effective dose (BED) in 90Y microsphere ra
Externí odkaz:
https://doaj.org/article/6ff16677738a429281e0ef33f260c406
Autor:
Jonathan D. Allred, Jeremy Niedbala, Justin K. Mikell, Dawn Owen, Kirk A. Frey, Yuni K. Dewaraja
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Background A major toxicity concern in radioembolization therapy of hepatic malignancies is radiation-induced pneumonitis and sclerosis due to hepatopulmonary shunting of 90Y microspheres. Currently, 99mTc macroaggregated albumin (99mTc-MAA)
Externí odkaz:
https://doaj.org/article/88ca165bd28242e3942fd09a03334ff2
Autor:
Silvano Gnesin, Justin K. Mikell, Maurizio Conti, John O. Prior, Thomas Carlier, Thiago V.M. Lima, Yuni K. Dewaraja
Publikováno v:
Journal of Nuclear Medicine. 64:825-828
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0dea16b15c454eb70955e00fcf56154
https://doi.org/10.2967/jnumed.122.264458
https://doi.org/10.2967/jnumed.122.264458
Publikováno v:
Med Phys
PURPOSE: Current methods for patient-specific voxel-level dosimetry in radionuclide therapy suffer from a trade-off between accuracy and computational efficiency. Monte Carlo (MC) radiation transport algorithms are considered the gold standard for vo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75cc9fef5339e0ac6a2312561f2598e
https://doi.org/10.1002/mp.15397
https://doi.org/10.1002/mp.15397
Autor:
Benjamin Van, Yuni K. Dewaraja, Jeremy T. Niedbala, Gerrid Rosebush, Matthew Kazmierski, David Hubers, Justin K. Mikell, Scott J. Wilderman
Publikováno v:
Medical physicsREFERENCES.
Validation of dosimetry software, such as Monte Carlo (MC) radiation transport codes used for patient-specific absorbed dose estimation, is critical prior to their use in clinical decision making. However, direct experimental validation in the clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba194fc1311e9c3a2143c87afd0c333
https://pubmed.ncbi.nlm.nih.gov/35983857
https://pubmed.ncbi.nlm.nih.gov/35983857
Autor:
Stephen F Mee, Daniel F Polan, Yuni K Dewaraja, Kyle C Cuneo, Joseph J Gemmete, Joseph R Evans, Theodore S Lawrence, Janell S Dow, Justin K Mikell
Publikováno v:
Physics in Medicine & Biology. 68:065003
Objective. 90Y selective internal radiation therapy (SIRT) treatment of hepatocellular carcinoma (HCC) can potentially underdose lesions, as identified on post-therapy PET/CT imaging. This study introduces a methodology and explores the feasibility f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa56242ebd5e00d8ee6f39d86470dc2d
https://doi.org/10.1088/1361-6560/acbbb5
https://doi.org/10.1088/1361-6560/acbbb5
Autor:
Yuni K Dewaraja, Elise C. Covert, Kellen Fitzpatrick, Justin K. Mikell, Ravi K. Kaza, John D. Millet, Daniel Barkmeier, Joseph Gemmete, Jared Christensen, Matthew J. Schipper
Purpose The aim was to quantify inter- and intra-observer variability in manually delineated lesion contours and the resulting impact on radionuclide therapy dosimetry. Methods Ten patients with hepatocellular carcinoma lesions treated with 90Y radio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18ad741ac69982e879665f77bd4caecf
https://doi.org/10.21203/rs.3.rs-1408164/v1
https://doi.org/10.21203/rs.3.rs-1408164/v1
Autor:
Yuni K. Dewaraja, David M Mirando, Avery Peterson, Jeremy Niedbala, John D Millet, Justin K Mikell, Kirk Frey, Ka Kit Wong, Scott Wilderman, Aaron S Nelson
Publikováno v:
J Nucl Med
Patient-specific dosimetry in radiopharmaceutical therapy (RPT) is impeded by the lack of tools that are accurate and practical for the clinic. Our aims were to construct and test an integrated voxel-level pipeline that automates key components (orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884fe9b9cda308b68748ec9dbf84c865
https://doi.org/10.2967/jnumed.121.263738
https://doi.org/10.2967/jnumed.121.263738
Publikováno v:
Medical physics. 46(1)
A modified NEMA IEC phantom was used to emulate clinically relevantIn a wide range of clinically relevant imaging conditions, using 36 equivalent iterations with a 5.2-mm filtration resulted in decreased systematic errors in volumetricOur proposed ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ce37a733dad4e2a9498918e31c4b821
https://pubmed.ncbi.nlm.nih.gov/30375655
https://pubmed.ncbi.nlm.nih.gov/30375655