Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Justin J. Montoya"'
Autor:
Justin J. Montoya, Megan A. Turnidge, Daniel H. Wai, Apurvi R. Patel, David W. Lee, Vijay Gokhale, Laurence H. Hurley, Robert J. Arceci, Cynthia Wetmore, David O. Azorsa
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Acute Myeloid Leukemia (AML) is a malignancy of myeloid precursor cells that arise from genomic alterations in the expression of key growth regulatory genes causing cells to assume an undifferentiated state and continue to prolife
Externí odkaz:
https://doaj.org/article/70b17a3e059a4dbc847f00fba0fb5ba6
Autor:
Vijay Gokhale, Robert J. Arceci, David W. Lee, Laurence H. Hurley, Megan A. Turnidge, Justin J. Montoya, Daniel H. Wai, Apurvi R. Patel, David O. Azorsa, Cynthia Wetmore
Publikováno v:
BMC Cancer
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Background Acute Myeloid Leukemia (AML) is a malignancy of myeloid precursor cells that arise from genomic alterations in the expression of key growth regulatory genes causing cells to assume an undifferentiated state and continue to proliferate. Rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b13ca6c0772b4e209beb8f1e65a737
http://europepmc.org/articles/PMC6935221
http://europepmc.org/articles/PMC6935221
Publikováno v:
Annals of Oncology. 30:vii20-vii21
Background The five-year-survival-rate for paediatric patients with Acute Myeloid Leukaemia (AML) is from 60-70%. The most common causes of death are disease relapse and chemo-resistance. Typically, drug dose response testing is performed at atmosphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c2a858a1ddf8005291e3e2a87e29c46
https://doi.org/10.1093/annonc/mdz413.073
https://doi.org/10.1093/annonc/mdz413.073
Autor:
Justin J. Montoya, Megan A. Turnidge, Daniel H. Wai, David W. Lee, Apruvi Patel, Vijay Gokhale, Laurence J. Hurley, David O. Azorsa
Publikováno v:
Cancer Research. 79:2967-2967
Acute Myeloid Leukemia (AML) is a malignancy of myeloid precursor cells that can occur when genomic changes alter expression of key genes, causing cells to resume an undifferentiated state and proliferate. Ongoing efforts have focused on developing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce3c0b31b360362c54018472e7c37b08
https://doi.org/10.1158/1538-7445.am2019-2967
https://doi.org/10.1158/1538-7445.am2019-2967
Autor:
Justin J, Montoya, David O, Azorsa
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1470
RNAi screening of mammalian cells is often performed using siRNAs and cationic lipids as transfection reagents. Efficiency of transfection depends on growth characteristics of the cells and the cationic lipid used. With a large selection of cationic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da6132ffad6de42b854498453243de8c
https://pubmed.ncbi.nlm.nih.gov/27581281
https://pubmed.ncbi.nlm.nih.gov/27581281
Autor:
Vijay Gokhale, Daniel H. Wai, David W. Lee, Laurence H. Hurley, Justin J. Montoya, David O. Azorsa, Robert J. Arceci, Apurvi Patel, Megan A. Turnidge
Publikováno v:
Cancer Research. 78:B04-B04
Acute myeloid leukemia (AML) is a disease that can affect both children and adults and is characterized by complex and heterogeneous genomic changes, including MYC overexpression driven in part by the bromodomain (BRD) and extraterminal (BET) protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae0b5d333bb777bdca818e138086b1a1
https://doi.org/10.1158/1538-7445.pedca17-b04
https://doi.org/10.1158/1538-7445.pedca17-b04
Publikováno v:
Cancer Research. 77:2349-2349
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and young adults. The five-year survival rate for RMS has hardly improved over the last three decades despite intensive and toxic chemotherapy, radiotherapy with surgery. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b63decf337b74cab87e0ffa16a11eb15
https://doi.org/10.1158/1538-7445.am2017-2349
https://doi.org/10.1158/1538-7445.am2017-2349
Autor:
David W. Lee, Justin J. Montoya, Daniel H. Wai, David O. Azorsa, Robert J. Arceci, Apurvi Patel
Publikováno v:
Cancer Research. 77:4077-4077
Patients with Down’s syndrome who develop acute myeloid leukemia (AML) are at increased risk of toxicity secondary to chemotherapy regimens. These patients are harder to treat with conventional therapies at relapse. Overall, the use of targeted dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a7583bd635f46e0e624885981c85359
https://doi.org/10.1158/1538-7445.am2017-4077
https://doi.org/10.1158/1538-7445.am2017-4077
Autor:
David O. Azorsa, Justin J. Montoya, Daniel H. Wai, Robert J. Arceci, David W. Lee, Oliver B. Pepper, Peter Azorsa
Publikováno v:
Cancer Research. 77:3338-3338
Ewing sarcoma is the second most common cancer of bone and soft tissue arising in children and young adults. Although the survival rate has improved for patients treated for localized disease, the survival rate for patients with metastatic tumor rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dffc1ad69fe4356d31284495a2b88d23
https://doi.org/10.1158/1538-7445.am2017-3338
https://doi.org/10.1158/1538-7445.am2017-3338
Abstract 5181: Targeted knockdown of MYC in AML cells using G-quadruplex interacting small molecules
Autor:
Vijay Gokhale, Robert J. Arceci, Megan A. Turnidge, Laurence H. Hurley, David O. Azorsa, Justin J. Montoya, Daniel H. Wai, David W. Lee, Apurvi R. Patel
Publikováno v:
Cancer Research. 77:5181-5181
Acute Myeloid Leukemia (AML) is a disease that occurs when genomic changes alter expression of key genes, causing cells to resume an undifferentiated state, proliferate, and maintain tumor growth throughout the body. Recently, there has been an incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cd81bb8a3663cfac5cd221f27d81db2
https://doi.org/10.1158/1538-7445.am2017-5181
https://doi.org/10.1158/1538-7445.am2017-5181