Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Justin J. Doel"'
Publikováno v:
Journal of Biological Chemistry. 281:30650-30659
A water-soluble aldose sugar dehydrogenase (Asd) has been purified for the first time from Escherichia coli. The enzyme is able to act upon a broad range of aldose sugars, encompassing hexoses, pentoses, disaccharides, and trisaccharides, and is able
Publikováno v:
Biochemical Journal. 358:325-333
Xanthine oxidoreductase (XOR) is progressively inactivated while catalysing the reduction of inorganic nitrite to NO by xanthine. Inactivation results from conversion of the enzyme into its desulpho-form. The rate of inactivation increases with nitri
Autor:
Hannah M. Martin, Adele Ainger, Robert Eisenthal, Justin J. Doel, Andrew R. Cross, Catherine Hoare, Paul J. Moulton, Roger Harrison, John T. Hancock
Publikováno v:
European Journal of Pharmacology. 401:115-120
Iodonium compounds, especially diphenylene iodonium and iodonium diphenyl are used extensively as inhibitors of NADH-ubiquinone reductase and NADPH oxidase activity. Here, the use of a new iodonium compound, phenoxaiodonium is reported. The IC(50) of
Publikováno v:
FEBS Letters. 475:93-96
Peroxynitrite, a potent oxidising, nitrating and hydroxylating agent, results from the reaction of nitric oxide with superoxide. We show that peroxynitrite can be produced by the action of a single enzyme, xanthine oxidoreductase (XOR), in the presen
Publikováno v:
Biochimica et biophysica acta. 1527(1-2)
Xanthine oxidoreductase catalyses the anaerobic reduction of glyceryl trinitrate (GTN), isosorbide dinitrate and isosorbide mononitrate to inorganic nitrite using xanthine or NADH as reducing substrates. Reduction rates are much faster with xanthine
Publikováno v:
Biochemical and biophysical research communications. 270(3)
Xanthine oxidase (XO) was shown to catalyze the reduction of isoamyl and isobutyl nitrites to nitric oxide (NO) in the presence of xanthine under anaerobic conditions. NO was produced at a stoichiometric ratio of 2:1 versus urate generation, steady-s