Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Justin H. Hickman"'
Publikováno v:
Nucleic acid therapeutics. 30(5)
In this study, we demonstrate that 5S ribosomal RNA (rRNA), a highly structured and protein-bound RNA, is quite difficult to reduce with antisense oligonucleotides (ASOs). However, we found a single accessible site that was targetable with a high-aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2248b23de3e5865c71f4edb0e74dcc38
https://pubmed.ncbi.nlm.nih.gov/32589504
https://pubmed.ncbi.nlm.nih.gov/32589504
Autor:
Xiuli Cong, Justin H. Hickman, Russel C. DeKelver, Luke F. Peterson, Dong-Er Zhang, Miao Chia Lo, Denise Niewerth, Ming Yan
Publikováno v:
Leukemia
Oncogenic mutations in components of the JAK/STAT pathway, including those in cytokine receptors and JAKs, lead to increased activity of downstream signaling and are frequently found in leukemia and other hematological disorders. Thus, small-molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3248e56fcb717e5f5b4a4c4a0148edf6
https://doi.org/10.1038/leu.2013.197
https://doi.org/10.1038/leu.2013.197
Publikováno v:
Cell cycle (Georgetown, Tex.). 14(18)
The p53 tumor suppressor is a multifaceted polypeptide that impedes tumorigenesis by regulating a diverse array of cellular processes. Triggered by a wide variety of stress stimuli, p53 transcriptionally regulates genes involved in the canonical tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d44ba86a4f8b746b0c8fc70d5243816
https://pubmed.ncbi.nlm.nih.gov/26218928
https://pubmed.ncbi.nlm.nih.gov/26218928