Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Justin H Trotter"'
Autor:
Sonya B Dumanis, Hyun-Jung Cha, Jung Min Song, Justin H Trotter, Matthew Spitzer, Ji-Yun Lee, Edwin J Weeber, R Scott Turner, Daniel T S Pak, G William Rebeck, Hyang-Sook Hoe
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17203 (2011)
Apolipoprotein E receptor 2 (ApoEr2) is a postsynaptic protein involved in long-term potentiation (LTP), learning, and memory through unknown mechanisms. We examined the biological effects of ApoEr2 on synapse and dendritic spine formation-processes
Externí odkaz:
https://doaj.org/article/746b792ebb2b4594be3396e2f48cfa3a
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
The presynaptic release probability is a major determinant of synaptic transmission in brain. Here, the authors show that a trans-synaptic signaling complex comprising presynaptic Neurexin-3 and postsynaptic dystroglycan controls the release probabil
Externí odkaz:
https://doaj.org/article/b4ea889eebb84b5e8ea3ec8edd3cdf02
Autor:
Hyun-ju Lee, Jin-Hee Park, Justin H. Trotter, James N. Maher, Kathleen E. Keenoy, You Mi Jang, Youngeun Lee, Jae-Ick Kim, Edwin J. Weeber, Hyang-Sook Hoe
Publikováno v:
Experimental Neurobiology. 32:42-55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4da380d972cf066ea4a944c2945d739
https://doi.org/10.5607/en22044
https://doi.org/10.5607/en22044
Astrocytic Neuroligins Are Not Required for Synapse Formation or a Normal Astrocyte Cytoarchitecture
Astrocytes exert multifarious roles in the formation, regulation, and function of synapses in the brain, but the mechanisms involved remain unclear. Interestingly, astrocytes abundantly express neuroligins, postsynaptic adhesion molecules that bind t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5c3ed40f3dc6e355ed384676bf89d22
https://doi.org/10.1101/2023.04.10.536254
https://doi.org/10.1101/2023.04.10.536254
Publikováno v:
Science advances, vol 9, iss 1
Neurexins are widely thought to promote synapse formation and to organize synapse properties. Here we found that in contrast to neurexin-1 and neurexin-3, neurexin-2 unexpectedly restricts synapse formation. In the hippocampus, constitutive or neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d708bb7b6ac4f5a5b3f9b7dcac8718dc
https://pubmed.ncbi.nlm.nih.gov/36608123
https://pubmed.ncbi.nlm.nih.gov/36608123
Disrupted synaptic inhibition is implicated in most psychiatric disorders, yet the molecular mechanisms that shape and sustain inhibitory synapses are poorly understood. Here, we find that the function of a subset of inhibitory synapses in brain is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f75bc57c7c097eb9e7e104d04bce9d46
https://doi.org/10.1101/2022.05.09.491206
https://doi.org/10.1101/2022.05.09.491206
Autor:
Cosmos Yuqi Wang, Justin H. Trotter, Kif Liakath-Ali, Sung-Jin Lee, Xinran Liu, Thomas C. Südhof
Publikováno v:
Science Advances
Description
Cbln1 binding to neurexins blocks inactive cis interactions and enables functional trans complexes of neurexins at synapses.
Synapses are thought to be organized by interactions of presynaptic neurexins with postsynaptic ligands
Cbln1 binding to neurexins blocks inactive cis interactions and enables functional trans complexes of neurexins at synapses.
Synapses are thought to be organized by interactions of presynaptic neurexins with postsynaptic ligands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195e3cf784adf37ccacb795102bdd46b
http://europepmc.org/articles/PMC8682996
http://europepmc.org/articles/PMC8682996
Autor:
Xinran Liu, Justin H. Trotter, Thomas C. Südhof, Kif Liakath-Ali, Sung-Jin Lee, Cosmos Yuqi Wang
SUMMARYReciprocal synapses are formed by neighboring dendritic processes that create the smallest possible neural circuit. Reciprocal synapses are widespread in brain and essential for information processing, but constitute a conceptual conundrum: Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71ad46c9582b92cccdb9213355222dba
https://doi.org/10.1101/2021.05.24.445461
https://doi.org/10.1101/2021.05.24.445461
Autor:
Sofia Essayan-Perez, Alessandra Sclip, Amber M. Nabet, Kif Liakath-Ali, Xinran Liu, Markus Wöhr, Thomas C. Südhof, Justin H. Trotter, Karthik Raju, Zahra Dargaei
At tripartite synapses, astrocytes enmesh synaptic contacts, but how astrocytes contribute to the formation, maturation and plasticity of synapses remains elusive. Here we show that both astrocytes and neurons abundantly express neurexin-1, a presyna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e4de6baa39490a3c6c91c9d9a8631a4
https://doi.org/10.1101/2020.08.21.262097
https://doi.org/10.1101/2020.08.21.262097
Autor:
Thomas C. Südhof, Chen Zhang, Fredrik H. Sterky, ChangHui Pak, Salomé Calado Botelho, Sung-Jin Lee, Mengping Wei, Justin H. Trotter, Stephan Maxeiner
Publikováno v:
The Journal of Neuroscience. 37:1062-1080
Three neuronal pentraxins are expressed in brain, the membrane-bound “neuronal pentraxin receptor” (NPR) and the secreted proteins NP1 and NARP (i.e., NP2). Neuronal pentraxins bind to AMPARs at excitatory synapses and play important, well-docume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171080f832750a9510c67ad90f4c8dd1
https://doi.org/10.1523/jneurosci.2768-16.2016
https://doi.org/10.1523/jneurosci.2768-16.2016