Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Justin Gibbons"'
Autor:
Chengqi Wang, Yibo Dong, Chang Li, Jenna Oberstaller, Min Zhang, Justin Gibbons, Camilla Valente Pires, Mianli Xiao, Lei Zhu, Rays H. Y. Jiang, Kami Kim, Jun Miao, Thomas D. Otto, Liwang Cui, John H. Adams, Xiaoming Liu
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Malaria remains one of the deadliest infectious diseases. Transcriptional regulation effects of noncoding variants in this unusual genome of malaria parasites remain elusive. We developed a sequence-based, ab initio deep learning framework,
Externí odkaz:
https://doaj.org/article/004e37fc75b5456aa0afc0c9d7b5baaa
Autor:
Caroline F. Simmons, Justin Gibbons, Min Zhang, Jenna Oberstaller, Camilla Valente Pires, Debora Casandra, Chengqi Wang, Andreas Seyfang, Thomas D. Otto, Julian C. Rayner, John H. Adams
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Artemisinin combination therapies (ACTs) have led to a significant decrease in Plasmodium falciparum malaria mortality. This progress is now threatened by emerging artemisinin resistance (ART-R) linked originally in SE Asia to polymorphisms
Externí odkaz:
https://doaj.org/article/c026f00fd7264522ba02acdaa84a39ae
Autor:
Caroline Simmons, Justin Gibbons, Chengqi Wang, Camilla Valente Pires, Min Zhang, Faiza Siddiqui, Jenna Oberstaller, Debora Casandra, Andreas Seyfang, Liwang Cui, Thomas D. Otto, John H. Adams
Publikováno v:
mSphere, Vol 8, Iss 4 (2023)
ABSTRACT The implementation of artemisinin (ART) combination therapies (ACTs) has greatly decreased deaths caused by Plasmodium falciparum malaria, but increasing ACT resistance in Southeast Asia and Africa could reverse this progress. Parasite popul
Externí odkaz:
https://doaj.org/article/2ff95d3581cb4cd393c7c8a9d3bf5298
Autor:
Mengmeng Chang, Kirin D. Gada, Bojjibabu Chidipi, Athanasios Tsalatsanis, Justin Gibbons, Elizabeth Remily-Wood, Diomedes E. Logothetis, Jenna Oberstaller, Sami F. Noujaim
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105442- (2022)
Summary: Atrial fibrillation (AF), the most common abnormal heart rhythm, is a major cause for stroke. Aging is a significant risk factor for AF; however, specific ionic pathways that can elucidate how aging leads to AF remain elusive. We used young
Externí odkaz:
https://doaj.org/article/3a87495203d64c7e927f8ce86dea274f
Publikováno v:
mSphere, Vol 6, Iss 5 (2021)
The gut bacterial flora influences the development of the immune system and long-term health outcomes in preterm infants. Studies of the mechanistic interactions between the gut bacteria and mucosal barrier are limited to clinical observations, anima
Externí odkaz:
https://doaj.org/article/76a58580d5dd405c88fa53b9efd8bcde
Autor:
Amanda Sales Conniff, Jared Tur, Kristopher Kohena, Min Zhang, Justin Gibbons, Loree C. Heller
Publikováno v:
Vaccines, Vol 10, Iss 12, p 2037 (2022)
Skeletal muscle is a promising tissue for therapeutic gene delivery because it is highly vascularized, accessible, and capable of synthesizing protein for therapies or vaccines. The application of electric pulses (electroporation) enhances plasmid DN
Externí odkaz:
https://doaj.org/article/e220f0b9fb4a448b90ae647bf68d5d35
Autor:
Justin Gibbons, Katrina A. Button-Simons, Swamy R. Adapa, Suzanne Li, Maxwell Pietsch, Min Zhang, Xiangyun Liao, John H. Adams, Michael T. Ferdig, Rays H. Y. Jiang
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background Plasmodium falciparum exhibits resistance to the artemisinin component of the frontline antimalarial treatment Artemisinin-based Combination Therapy in South East Asia. Millions of lives will be at risk if artemisinin resistance (
Externí odkaz:
https://doaj.org/article/61e03efb695f4bd0ad5c8b1ab6e0e5ce
Autor:
Gloria C. Ferreira, Jenna Oberstaller, Renée Fonseca, Thomas E. Keller, Swamy Rakesh Adapa, Justin Gibbons, Chengqi Wang, Xiaoming Liu, Chang Li, Minh Pham, Guy W. Dayhoff II, Linh M. Duong, Luis Tañón Reyes, Luciano Enrique Laratelli, Douglas Franz, Segun Fatumo, ATM Golam Bari, Audrey Freischel, Lindsey Fiedler, Omkar Dokur, Krishna Sharma, Deborah Cragun, Ben Busby, Rays H.Y. Jiang
Publikováno v:
F1000Research, Vol 8 (2019)
Background: Basic and clinical scientific research at the University of South Florida (USF) have intersected to support a multi-faceted approach around a common focus on rare iron-related diseases. We proposed a modified version of the National Cente
Externí odkaz:
https://doaj.org/article/4a7ad9b62dfe44e2ad3ff1c09b932936
Autor:
Amanda Sales Conniff, Jared Tur, Kristopher Kohena, Min Zhang, Justin Gibbons, Loree C. Heller
Publikováno v:
Bioelectricity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd160d8949c8635c4988257e4d80f293
https://doi.org/10.1089/bioe.2022.0041
https://doi.org/10.1089/bioe.2022.0041
Group B Streptococcus (GBS) is a leading cause of infant sepsis worldwide. Colonization of the gastrointestinal tract is a critical precursor to late-onset disease in exposed newborns. Neonatal susceptibility to GBS intestinal translocation stems fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::321368e3b4bc6b1a9806b7c493026630
https://doi.org/10.1101/2023.01.24.525471
https://doi.org/10.1101/2023.01.24.525471
